Image 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Data Sheet 1_Exploring AI-personalized visualization of the safe place in virtual reality versus imagination of the safe place for stress, burnout, and relaxation in psychotherapis... by Viktoria Wollweber (22651739)

“…Burnout and stress did not significantly decrease over time and VR did not yield significantly greater effects on all outcomes. …”

Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributable to lead exposure, 1990–2021: decomposition, frontier, and projection analysis.docx by Xinyue Wen (20539088)

“…Introduction<p>Ischemic heart disease (IHD) is a leading global health burden, with lead exposure identified as a significant environment risk factor contributing to its prevalence.…”

Table 2_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.docx by Arushi Dagar (22287460)

“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”

Data Sheet 2_Identification and validation of paraptosis-related biomarkers in recurrent miscarriage.pdf by Yunhui Wan (18795185)

“…ScRNA-seq analysis identified decidual natural killer (dNK) cells and macrophages as key cell types, with ELOA expression decreasing in dNK cells as their state changed, while in macrophages, expression followed a pattern of increase, decrease, and increase again.…”

Table 2_Dose-optimized microbial inoculants reshape grape rhizosphere microbiota and enhance fruit quality.xlsx by Xiaojian Chang (738291)

“…</p>Results<p>The results indicated that inoculant application significantly increased the relative abundance of bacterial phyla Proteobacteria and Actinobacteria, along with the genera Bacillus, Nitrospira, and Pseudomonas. …”

Data Sheet 1_Multi-scenario assessment of landscape ecological risk in the transitional zone between the warm temperate zone and the northern subtropical zone.pdf by Chenghang Li (14266791)

“…Over the past 20 years, the risk initially increased and then decreased, and by 2030, the risk was expected to decline further. (3) The risk exhibited significant positive spatial autocorrelation. …”

Data Sheet 1_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf S... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …”

Table 1_Gut microbiome alterations and their clinical and biological implications in ovarian cancer: a systematic review.docx by Beibei Zhang (509356)

“…Following surgery, both Firmicutes and Proteobacteria declined, indicating significant microbiome shifts. During chemotherapy, especially neoadjuvant treatment, Firmicutes re-emerged as the dominant phylum. …”

Data Sheet 4_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.csv by Po-Chun Liu (676035)

“…Additionally, we identified an increase in the ARGORNPROST-PWY pathway (L-arginine degradation, q = 0.003) and a decrease in the PWY-6478 pathway (GDP-D-glycero-α-D-manno-heptose biosynthesis, q = 0.015) in MSA patients compared with HCs.…”

Data Sheet 2_Exploring the role of neutrophils in inflammatory pain hypersensitivity via single-cell transcriptome profiling.xlsx by Kai Ding (783198)

“…</p>Results<p>scRNA-seq revealed a significant increase in neutrophils and a decrease in monocytes among CD11b⁺ cells following surgery and CFA treatment. …”

Table 1_Managing lorlatinib-induced weight gain through a structured exercise intervention in an ALK+ NSCLC patient: a case report.docx by Christian Ciurnelli (20548178)

“…Background<p>In non-small cell lung cancer (NSCLC), ALK tyrosine kinase inhibitors (TKIs) have been associated with significant weight gain, predominantly in fat tissues. …”

Data Sheet 1_Longitudinal analysis of coal workers’ pneumoconiosis using enhanced resolution-computed tomography images: unveiling patterns in lung structure, function, and clinica... by Ngan-Khanh Chau (17437641)

“…</p>Results<p>The study identified significant airway changes in angles, diameters, and geometry, with a decrease in normal lung tissue in the right upper lobe. …”

Table 1_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.docx by Arushi Dagar (22287460)

“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”

Image 6_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.tif by Arushi Dagar (22287460)

“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”

Alleviation of Nanoplastic Stress in Rice: Evidence from Biochemical, Cytological, Physiological, and Transcriptome Analysis by Jiacheng Jin (11480055)

“…These two remedies were cost-effective and environmentally favorable, offering significant potential benefits for agricultural sustainability.…”

Table_1_Higher oxidative balance score is associated with lower female infertility: a cross-sectional study.DOCX by Xiong Lei (3847897)

“…Multifactorial logistic regression showed a 5% decrease in infertility for each unit increased in OBS (OR, 0.95; 95% CI, 0.92 to 0.98). …”

Image 2_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …”

Data Sheet 1_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.docx by Jiaqi Liu (309587)

“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”

Table3_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studies.x... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”