Table 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.xlsx by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”

Image 2_Case Report: Is there an age cutoff beyond which PFO closure should not be offered?.jpeg by Eustaquio Maria Onorato (11277405)

“…Two-dimensional (2D) transthoracic/transesophageal echocardiography (TTE/TEE) color Doppler showed a significant right-to-left shunt (RLS) via a tunnel-type PFO associated with hypermobile floppy septum primum (HSP) and prominent Eustachian valve (EV). …”

Data Sheet 1_Global burden of disease for colorectal cancer due to diet low in whole grains from 1990 to 2021 and its projections to 2050: analysis of the global burden of disease... by Mei Yang (51996)

“…</p>Results<p>Between 1990 and 2021, the number of CRC deaths associated with a low proportion of whole grain diets worldwide increased by 82.94%, and disability adjusted life years increased by 70.3%. There is significant heterogeneity between regions: regions with high Social Population Index (SDI) have the highest decrease rate, while regions with low to medium SDI have the fastest increase rate. …”

Table 1_Influence of different scion-rootstock combinations on sugars, polyamines, antioxidants and malondialdehyde in grafted grapevines under arid conditions.docx by Sonu Krishankumar (10829367)

“…The shoots improved sugar metabolism, which led to increased resistance to drought. There was a significant increase in glucose sugar content at 75% and 50% FC, which was 85.7% to 133% at V1, 19% to 76.9% at V2, and decreased by 30% and 53% at V4.…”

Data Sheet 2_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip by Yimin Zhou (3857113)

“…Animal experiments confirmed a significant decrease in the behavioral scores of rats in the SCI group, pathological changes in tissue sections, and differential expression of candidate genes in the SCI rat model.…”

Data Sheet 2_Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990–2021 analysis and future projections.docx by Ming Liu (105953)

“…</p>Results<p>From 1990 to 2021, the global burden of AGN among children and adolescents remained significantly high. In 2021, there were approximately 170,584 new cases, representing a decrease compared to earlier years, with an age-standardized incidence rate (ASIR) of 6.47 per 100,000 (95% UI: 4.79–8.45). …”

Supplementary file 1_Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period.docx by Yingyu He (13877876)

“…On the 21st day of CS-WB storage, the oxygen carrying capacity and ATP content of RBCs showed a more significant decrease. Platelets showed characteristic ultrastructural damage and progressive decline in hemostatic function. …”

Data Sheet 1_Epidemiological trends and age-period-cohort effects on subarachnoid hemorrhage burden across the BRICS-plus from 1992 to 2021.docx by Liang Guo (95092)

“…Indonesia reported the highest age-standardized incidence rate (10.94 per 100,000 population) in 2021, while China displayed the most significant decrease, at 59.36%. The annual net drift in the SAH incidence rate ranged from −3.36%% for China to −0.50% for the Russian Federation among the eleven countries. …”

Table 1_Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study.xlsx by Can Qian (10906868)

“…Through targeted management, some antibiotics showed trends of increased or decreased usage. The detection rates of Methicillin-Resistant Staphylococcus aureus and Extended-spectrum β-lactamase-producing Escherichia coli did not show a significant decrease.…”

Table_1_Regional and social disparities in cessation behavior and motivation to quit among U.S. adult current smokers, Tobacco Use Supplement to the U.S. Census Bureau's Current Po... by Candon Johnson (11572623)

“…Notably, the Asian non-Hispanic group in the Northeast experienced a significant decrease in quit interest (–17.9%) but an increase in recent successful cessation (+369.2%).…”

Data Sheet 1_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip by Yimin Zhou (3857113)

“…Animal experiments confirmed a significant decrease in the behavioral scores of rats in the SCI group, pathological changes in tissue sections, and differential expression of candidate genes in the SCI rat model.…”

Data Sheet 3_Deep crustal composition and Late Paleozoic geotectonic evolution in West Junggar, China.pdf by Shenglin Xu (12076840)

“…During the Early Permian-Early Triassic period (272–250 Ma), magmatic activity decreased significantly, where the southwestern region experienced high-temperature, low-pressure, crustal thinning extension. …”

Data Sheet 4_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Image 5_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”

Image 1_Temporal trends of cervical cancer demographics: a CDC WONDER database study.png by Grace Folino (21738503)

“…Between 2015 and 2023, there was a concerning positive change in AAMR [APC of 0.1272 (95% CI –0.3393 to 1.7502)], though not statistically significant. Black or African American patients experienced the highest AAMR across races but maintained a decrease in mortality rate over the study period [AAPC of -2.670* (95% CI -2.931 to -2.356)]. …”

Figure S5 from Immunoproteasome Activation Expands the MHC Class I Immunopeptidome, Unmasks Neoantigens, and Enhances T-cell Anti-Myeloma Activity by Priyanka S. Rana (15136410)

“…Compound A induced a marked decrease in PD-1 surface expression, while no significant change was observed in TIM-3, CTLA-4, and LAG-3.…”

Data Sheet 1_The association between the gut microbiome and antituberculosis drug-induced liver injury.docx by Shengfei Pei (20852069)

“…</p>Results<p>Following anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P < 0.05). …”

DataSheet1_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Table1_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table 1_The effectiveness of exercise interventions in the improvement of sleep in older adult people: a meta-analysis.docx by Di Geng (1681915)

“…Background<p>Sleep problems are prevalent among the older adult population, with a significant impact on their health and overall well-being. …”