Table 1_Hesperidin alleviates hypothyroidism-related cardiac dysfunction by targeting cardiac miRNAs, Nrf2/NF-κB signaling, oxidative stress and inflammation.docx by Asmaa M. Gaber (21640814)

“…</p>Results<p>CMZ intake resulted in a significant decrease in thyroid hormones (THs) levels with a subsequent increase in serum thyroid stimulating hormone and cardiac enzymes activities, dyslipidemia, and body weight gain. …”

Data Sheet 1_miR-198 targets TOPORS: implications for oral squamous cell carcinoma pathogenesis.pdf by Pankhuri Kaushik (20381022)

“…Delivery of a synthetic miR-198 mimic to OSCC cells results in a significant decrease in xenograft size in nude mice, potentiating its use in therapeutics.…”

Image 3_Identification of immune subtypes associated with CD8+ T cell-related genes providing new treatment strategies of esophageal carcinoma.pdf by Youyi Wu (20786402)

“…</p>Results<p>The results revealed significant correlations between CD8+ T cell-related genes and immune-related pathways. …”

Image 1_Global patterns and health impact of unintentional injuries among children and adolescents, 1990–2021.tif by Wei Wei (21173)

“…Among the five socio-demographic index (SDI) regions, the low-middle SDI region exhibited the most significant decrease in injury incidence. Regionally, from 1990 to 2021, the Caribbean experienced the largest relative increase in injury incidence (EAPC 0.25, 95% CI: −0.60 to 1.11). …”

Table_3_Proteomics fingerprinting reveals importance of iron and oxidative stress in Streptomyces scabies–Solanum tuberosum interactions.docx by Lauriane Giroux (19779051)

“…The increase in the abundance of proteins related to pyochelin biosynthesis was consistent with a significant decrease in the iron content in the culture medium, as well as with induction of expression of pyochelin biosynthesis genes. …”

FCM analysis (%). by Takanori Kitagawa (20727226)

“…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …”

Image 1_Alteration of vasopressin-aquaporin system in hindlimb unloading mice.tif by Marianna Ranieri (330759)

“…Conversely, in 4 weeks HU suspended mice, copeptin decreased significantly and both AQP2 mRNA and AQP2 total protein expression were significantly reduced. …”

Neural timescales increase with cognitive demands. by Isabel Raposo (21615517)

“…Timescales in the period following search display onset (red dashed line) and after button press (black dashed line) decrease in pop-out condition relative to visual search condition returning to baseline around 1s (black bar represents significant time points <i>p</i> < 0.05). …”

Table 1_Joint association of sleep patterns and oxidative balance score with all-cause and cardiovascular mortality among the general population.docx by Chen Chen (6544)

“…Each point increase in OBS was associated with a 3% decrease in both all-cause mortality and CVD mortality. …”

Table 1_Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021.docx by Yue Li (102191)

“…Compared with 1990, although the ASIR and age-standardized disability-adjusted life years rate (ASDALYsR) decreased, absolute numbers increased significantly. …”

Cold ischemia time alters cell-type specific senescence leading to loss of cellular integrity in mouse lungs by Gagandeep Kaur (1458919)

“…Co-immunolabelling revealed the endothelial cells to be most affected by cold ischemia, demonstrating significant decrease in the endothelial cell senescence immediately after harvest. …”

Data Sheet 1_Case Report: Allogeneic adipose-derived mesenchymal stem cells for severe feline chronic kidney disease.pdf by Yizhe Song (11859734)

“…Concurrently, laboratory results revealed a decrease in key renal biomarkers (SCr, BUN, and P) and an amelioration of the non-regenerative anemia. …”

Table1_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx by Bing Cui (179696)

“…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …”

Data Sheet 1_Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers.docx by Sergio Sánchez-García (16862127)

“…We found reduced levels in deceased patients when compared to mild or severe patients, concomitant with a decrease in the LXA₄ biosynthetic pathway and an increase in its degradation pathway. …”

Experimental procedure flow. by Yanxu Liang (22227024)

“…The study shows that: (1) With the increase of unloading amplitude, there is an increase in the number of nascent cracks and a tendency to expand, which is caused by shear extension cracks; with the increase of unloading amplitude, there is a tendency for the microporosity to shift to the mesoporosity, and the mesoporosity has a tendency to shift to the macroporosity, and there is a decrease in the number of micropores as a whole, which indicates that there is almost no new pore sprouting. (2) When the unloading amplitude is less than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen increase slowly; when the unloading amplitude is more than 20MPa, with the increase of the unloading amplitude, the pore ratio and expansion rate of the specimen have a significant tendency to increase. (3) With the increase of unloading amplitude, the shale shear strength limit value decreases more slowly, the modulus of elasticity and shear strength also show a similar pattern of change, and the same way to derive the rock Poisson’s ratio does not change much.…”

Data Sheet 1_Innovative functional juice enriched with native probiotics for enhanced nutrition and antimicrobial properties.docx by Gabriela N. Tenea (10930824)

“…</p>Results<p>The results showed greater cell viability of Cys5-4 (8.84 ×10⁷ CFU/ml), whereas a statistically significant (p < 0.05) decrease was registered for LP strain (1.90 × 10⁵ CFU/mL) on the 15th day of storage with refrigeration. …”

Data Sheet 1_Development of an LC-MS/MS method for astaxanthin quantification in shrimp tissues and its application to detect astaxanthin variations during ovary development stages... by Shuo Diao (1967698)

“…During the ovarian developmental stages, astaxanthin was predominantly sequestered in the hepatopancreas during early phases, with concentrations ranging from 21.3 μg/g to 29.1 μg/g, representing a 43- to 59-fold increase compared to ovarian concentrations. However, a significant redistribution of astaxanthin was observed during the post-developmental stage, characterized by a substantial decrease to 5.74 μg/g in the hepatopancreas, concomitant with an increase to 7.47 μg/g in ovarian tissue.…”

Table1_The long-term effect of biochar application to Vitis vinifera L. reduces fibrous and pioneer root production and increases their turnover rate in the upper soil layers.docx by Peter Beatrice (12859252)

“…Our findings demonstrate that in the long term, biochar application significantly increased soil pH, nutrient availability, and water-holding capacity causing a decrease in the production of fibrous and pioneer roots which is reflected in a reduction of the root web characterized though by a higher turnover rate. …”

Analysis of biases in amplicon coverage across samples sequenced with diverse Ampliseq-based protocols (DDD/IDI/III – corresponds to variations of PCR mix1 (I/D), ligase/buffer (I/... by P.A. Shatalov (21485215)

“…<p><b>(A)</b> – heatmap of amplicon coverage (% of average coverage) across samples demonstrates significant variation in per-sample set of dropped out (10% of average sample coverage) amplicons depending on <b>i)</b> PCR mix 2 used <b>ii)</b> Digest Mix used. …”

Table 3_Global burden of low back pain and its attributable risk factors from 1990 to 2021: a comprehensive analysis from the global burden of disease study 2021.docx by Yue Li (102191)

“…Compared with 1990, although the ASIR and age-standardized disability-adjusted life years rate (ASDALYsR) decreased, absolute numbers increased significantly. …”