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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), gy decreased (Expand Search)
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13201
Table 1_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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13202
Table 1_Global, regional, and national burden of atrial fibrillation/flutter attributable to metabolic, behavioral, and environmental risk factors, 1990–2021: a longitudinal observ...
Published 2025“…Smoking showed the greatest decrease, with AAPCs of ASMR and ASDR at −0.66 (95% CI: −0.68 to −0.65) and −0.72 (95% CI: −0.72 to −0.71), most significantly in women aged 30–34. …”
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13203
Table 5_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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13204
Data Sheet 2_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e...
Published 2025“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”
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13205
Data Sheet 1_Enabling immune checkpoint blockade efficacy in T-lymphopenia by restoring CD8 T cell dynamics with IL-7 cytokine therapy.docx
Published 2024“…The combination of rhIL-7-hyFc and anti-PD-1 therapy resulted in significant tumor regression and improved mouse survival.…”
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13206
Data Sheet 1_Glucocorticoids and immunoglobulin alone or in combination in the treatment of multisystemic inflammatory syndrome in children: a systematic review and network meta-an...
Published 2025“…</p>Conclusions and relevance<p>GCs monotherapy significantly reduces treatment failure rates and persistent fever duration, while combination therapy significantly reduces the need for adjunctive immunotherapy. …”
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13207
Table 4_The dysbiosis of gut microbiota and dysregulation of metabolites in IgA nephropathy and membranous nephropathy.xlsx
Published 2025“…Notably, both IgAN and MN patients showed a decrease in the abundance of certain specific microbial taxa. …”
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13208
Data Sheet 1_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e...
Published 2025“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”
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13209
Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF
Published 2025“…The deficits in hippocampal-dependent learning and memory were accompanied by altered hippocampal neurogenesis, with an overall decrease in the proliferation and differentiation of newborn neurons within the dentate gyrus. …”
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13210
Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis
Published 2025“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC<sub>50</sub> values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”
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13211
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
Published 2024“…Although the development of DYRK1A inhibitors has significantly advanced in recent years, the selectivity of these drugs remains a critical challenge, potentially impeding further progress. …”
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13212
Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF
Published 2025“…The deficits in hippocampal-dependent learning and memory were accompanied by altered hippocampal neurogenesis, with an overall decrease in the proliferation and differentiation of newborn neurons within the dentate gyrus. …”
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13213
Bioassay and NMR-HSQC-Guided Isolation and Identification of Phthalide Dimers with Anti-Inflammatory Activity from the Rhizomes of Angelica sinensis
Published 2025“…Among them, compound <b>9</b> showed a remarkable inhibitory activity with IC<sub>50</sub> values of 425 nM and could significantly decrease IL-1β and IL-6 transcription levels. …”
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13214
Effects of Nitro-Substitution on the Spectroscopic and Self-Assembly Properties of BODIPY Dyes
Published 2025“…In a polar organic solvent, nitro-substitution tends to quench the characteristic fluorescence of BODIPYs, while in a nonpolar solvent, significantly higher absolute fluorescence quantum yields are observed. …”
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13215
Presentation_1_Src Inhibition Attenuates Neuroinflammation and Protects Dopaminergic Neurons in Parkinson’s Disease Models.PDF
Published 2025“…The results showed that inhibition of Src could significantly relieve microgliosis and decrease levels of inflammatory factors. …”
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13216
Predicting the potential distribution of <i>Arisaema heterophyllum</i> in China under current and future climate change based on ArcGIS and MaxEnt model
Published 2024“…<p>Climate change significantly affects the distribution of medicinal plants, necessitating accurate models to predict future shifts in their habitats. …”
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13217
OMT
Published 2024“…<p dir="ltr">In this study, we performed a series of experiments to investigate the effects of oxymatrine (OMT) on hemangioma cells and its mechanisms. OMT was found to significantly increase the apoptosis rate of endothelial cells (ECs) treated with oxidised low-density lipoprotein (ox-LDL), as measured by caspase-3 activity assay and flow cytometry. qRT-PCR results showed that OMT treatment decreased the expression of miR-199a-5p in ECs.Transfection of miR-199a-5p mimics enhanced the apoptotic effect, whereas miR-199a-5p inhibitors attenuated apoptosis, suggesting that miR-199a-5p has a key regulatory role in EC apoptosis. …”
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13218
Data Sheet 1_A ROS-responsive, aptamer-targeted graphene oxide nanocomposite for site-specific glutathione release in cerebral ischemia-reperfusion injury.docx
Published 2025“…In vitro, GO@GSH-FA significantly restored viability in oxygen-glucose-deprived SH-SY5Y cells (from 31% up to near control levels), reduced inflammatory cytokines, and lowered intracellular ROS. …”
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13219
DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP
Published 2024“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”
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13220
Data from "A Historical Misstep: Niche Shift to Specialisation Is Pushing Insular Ginger Towards an Evolutionary Dead End"
Published 2025“…<i>Z. shuanglongense</i>, as the specialist, despite an initial increase during the Last Glacial Maximum (~22 Kya), has been subjected to a long-term decrease in effective population size (<i>Ne</i>), while <i>Z. pleiostachyum</i> is on the contrary increasing, leading to a significantly larger current <i>Ne</i>. …”