يعرض 15,961 - 15,980 نتائج من 16,164 نتيجة بحث عن '(( significantly ((mean decrease) OR (we decrease)) ) OR ( significant increase decrease ))', وقت الاستعلام: 0.51s تنقيح النتائج
  1. 15961

    Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif حسب Bojun Chen (317487)

    منشور في 2025
    "…Simultaneously, CAVO reduced the expression of proteins in the endoplasmic reticulum stress pathway (CHOP, pPERK, CHOP, GRP78), the inflammatory factor NLRP3, and the apoptosis pathway (BAX, Bcl-2, Caspase3) (p < 0.05), increased Bcl-2 protein expression (p < 0.05). It also significantly reduced the mRNA expression of CHOP, NLRP3, GRP78, and BAX (p < 0.01).…"
  2. 15962

    Data Sheet 1_Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition.docx حسب Xiaoting Gu (3368495)

    منشور في 2025
    "…Gut microbiota analysis revealed that Deg-AZM altered the community composition by decreasing Deferribacterota and Pseudomonadota and increasing Bacteroidota, Lactobacillus and Muribaculaceae. …"
  3. 15963

    Image 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf حسب Yuanbing Zhu (20538638)

    منشور في 2025
    "…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. …"
  4. 15964

    Table 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

    منشور في 2025
    "…Background<p>Blunt chest trauma, commonly caused by traffic accidents, falls, and violent incidents, results in both direct mechanical injury to the thoracic cavity—leading to increased intrathoracic pressure and vascular rupture—and indirect effects on the central nervous system (CNS), causing extensive damage that severely impacts patient health and quality of life. …"
  5. 15965

    Supplementary file 1_Petroselinum sativum (Parsley) extract suppresses oxidative stress and inflammatory responses in human keratinocytes and reduces atopic dermatitis symptoms in... حسب Juan Wang (115708)

    منشور في 2025
    "…The results showed that HE extracts of parsley (HEP) contained the highest TPC and TFC and exhibited the strongest antioxidant activity, significantly improving cell viability and reducing ROS levels in t-BHP-treated cells. …"
  6. 15966

    Data Sheet 1_Aperiodic brain activity changes in patients with stroke following virtual reality-based upper limb robotic rehabilitation: a pilot Randomized Controlled Trial.docx حسب Maria Cristina Mauro (22449604)

    منشور في 2025
    "…</p>Results<p>At T0, the SEI in the sensorimotor cluster of the AH was significantly lower than in the UH. At T1, the SEI in the AH increased together with clinical improvements in upper limb motor function. …"
  7. 15967

    Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke حسب Yike Wu (20982007)

    منشور في 2025
    "…Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …"
  8. 15968

    Supplementary file 1_Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.xlsx حسب Linxi Wang (3068649)

    منشور في 2025
    "…Regarding the autophagy pathway, PPARGC1B, LC3B, and PGC1α expression levels were increased, while P62 and Parkin levels were decreased. …"
  9. 15969

    Image 3_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg حسب Chenchao Zou (22768010)

    منشور في 2025
    "…</p>Results<p>GA treatment decreased PTGS2, lactate dehydrogenase, malondialdehyde, ferrous iron, ROS, and oxidized glutathione disulfide (GSSG) levels and increased cell viability, glutathione (GSH) levels, the GSH/GSSG ratio, and GPX4 protein levels in the injury models. …"
  10. 15970

    Table 1_Optimization of Artemisia ordosica crude polysaccharides on milk fatty acid composition in lactating donkeys and their effects on rectal microbiome and lactation performanc... حسب Fanzhu Meng (20418071)

    منشور في 2025
    "…AOCP elevated acetate and butyrate in the rectum and the activity of enzymes related to lipid metabolism such as stearoyl-CoA desaturase, and increased the relative abundance of beneficial bacteria (Eubacterium hallii group, Prevotella, Ruminococcus), while decreasing potentially pathogenic bacteria Streptococcus and norank_f_Lachnospiraceae. …"
  11. 15971

    Table 1_Effects of education level on natural language processing in cardiovascular health communication.xlsx حسب Stanley Joseph (19282225)

    منشور في 2025
    "…</p>Results<p>Readability decreased significantly with increasing education level across all models (p < 0.001). …"
  12. 15972

    Image 3_Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus.tif حسب Alberto Pauletti (10920690)

    منشور في 2025
    "…They resumed proliferation at 14 dpi, but, did not recover to CTR levels, and displayed aberrant migration patterns. (2) The number of proliferating NSCs significantly decreased within the dorsal DG of TMEV mice at 14 dpi compared to CTR, while (3) a heightened population of proliferating astrocytes was observed. …"
  13. 15973

    Table 1_The trajectory of intrinsic capacity and its related factors among elderly Chinese patients with cardiovascular disease: a prospective cohort study.docx حسب Yanyin Cui (21428879)

    منشور في 2025
    "…</p>Results<p>The GBTM model identified three categories of IC trajectories among elderly patients with CVD: the low-decreased group (n=162, 23.11%), the high-increased group (n=196, 27.96%), and the medium-stable group (n=343, 48.93%). …"
  14. 15974

    Image 4_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif حسب Yuanbing Zhu (20538638)

    منشور في 2025
    "…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. …"
  15. 15975

    Image 4_Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus.tif حسب Alberto Pauletti (10920690)

    منشور في 2025
    "…They resumed proliferation at 14 dpi, but, did not recover to CTR levels, and displayed aberrant migration patterns. (2) The number of proliferating NSCs significantly decreased within the dorsal DG of TMEV mice at 14 dpi compared to CTR, while (3) a heightened population of proliferating astrocytes was observed. …"
  16. 15976

    Different types of participants have different responses to exposure to new normative environments: Judgment changes. حسب Claire Lugrin (21156528)

    منشور في 2025
    "…The colors represent the 4 different environments: A+ (Action + , frequent prosocial action) and J+ (Judgment + , strict judgment) are normative environments increasing prosocial actions, and A- (action -, frequent selfish action) and J- (Judgment -, lenient judgments) normative environments decreasing prosocial actions. …"
  17. 15977

    Presentation 1_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.pptx حسب Chenchao Zou (22768010)

    منشور في 2025
    "…</p>Results<p>GA treatment decreased PTGS2, lactate dehydrogenase, malondialdehyde, ferrous iron, ROS, and oxidized glutathione disulfide (GSSG) levels and increased cell viability, glutathione (GSH) levels, the GSH/GSSG ratio, and GPX4 protein levels in the injury models. …"
  18. 15978

    Image 2_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif حسب Yuanbing Zhu (20538638)

    منشور في 2025
    "…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. …"
  19. 15979

    Supplementary file 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

    منشور في 2025
    "…Background<p>Blunt chest trauma, commonly caused by traffic accidents, falls, and violent incidents, results in both direct mechanical injury to the thoracic cavity—leading to increased intrathoracic pressure and vascular rupture—and indirect effects on the central nervous system (CNS), causing extensive damage that severely impacts patient health and quality of life. …"
  20. 15980

    Table 4_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

    منشور في 2025
    "…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"