Data Sheet 2_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.docx by Yanxian Gao (20555714)

“…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…”

Data Sheet 1_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.csv by Yanxian Gao (20555714)

“…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…”

Supplementary Material for: Construction of a hybrid vaccine based on Der f 35-derived peptides with reduced allergenicity by Hu H. (4145581)

“…The IgE-reactivity of Der f 35 could be blocked by the vaccine induced IgG (p < 0.01). The levels of IL-5 and IL-13 from PBMCs were significantly decreased after stimulation by the vaccine than that by Der f 35 (p < 0.05). …”

Supplementary Material for: Abnormal Magnetic Resonance Imaging in the Medial Prefrontal Cortex Following Prenatal Alcohol Exposure and Placental Insufficiency in a Preclinical Mod... by figshare admin karger (2628495)

“…In the corpus callosum, the prenatal exposure/insult significantly decreased the AD (p<0.05; PAE+PI AD: 5.00x10-4 ± 4.60x10-5 mm2/s). …”

Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Table 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Image 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Table 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Data Sheet 1_Comparative evaluation of artificial saliva and complete artificial saliva as solvent vehicles for in vitro toxicity testing of oral tobacco products.docx by Xuefei Cao (1700068)

“…In the organotypic tissue models, both AS and CAS reduced IL-6 secretion without significantly affecting IL-8 levels.</p>Conclusion<p>These findings emphasize the importance of evaluating additional biological responses alongside cytotoxicity in vehicle control studies. …”

Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Table 6_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Table 5_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Table_1_Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.DOCX by Jie Zhou (28945)

“…However, an increase in ALI levels was associated with a decreased risk. HRs (95% CI) of 0.76 (0.65–0.90), 0.70 (0.57–0.86), and 0.51 (0.41–0.64) in the Q2, Q3, and Q4 of ALI compared with the Q1 of ALI, respectively. …”

Data Sheet 1_Spatiotemporal analysis of the burden of lower respiratory infections in the older adult population due to air pollution: trends from 1990 to 2021 and predictions for... by Zheng Lei (2250328)

“…Background<p>Lower respiratory infections (LRI), caused by various pathogens, have significant impacts on global health. Air pollution is a major environmental factor in the development of LRI, and with ongoing urbanization and industrialization, it has become a critical public health concern. …”

Data Sheet 1_Dynamics and drivers of the carbonate system: response to terrestrial runoff and upwelling along the Northeastern Colombian Caribbean coast.pdf by Constanza Ricaurte-Villota (14169471)

“…The observed trends in pH and pCO₂ were driven by a decrease in DIC and TA, attributed to increased river runoff, contrasting with typical ocean acidification trends driven by rising atmospheric CO₂ levels.…”

Deleterious Effects of a GAD65 Monoclonal Autoantibody on Islet Function by Christiane S. Hampe (248347)

“…GAD65mAb also reduced insulin secretion <i>in vivo</i> where decreased insulin levels after IP injection of glucose were observed in rats after IP injection of GAD65mAb. …”

Atorvastatin neuronal morphology data_CP.xlsxData set: neuronal morphology by Carolyn Pytte (20641508)

“…However, we found that neuronal soma morphology differed significantly between statin-treated and control birds. …”

Table 1_Near-infrared prediction of total phosphorus in leaves content in korla fragrant pear with growth period specificity via spectral modeling.docx by Mingyang Yu (7456358)

“…Compared with the general model, the Coefficient of determination (R²) increased by 0.05-0.16, and the root mean square error decreased by 0.0029-0.0079. This study successfully constructed a technical system of “Growth period-Preprocessing-Model”. …”