Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

"…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …"

Data Sheet 4_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf حسب Erman Wu (19021269)

"…</p>Methods<p>Using Global Burden of Disease 2021 data from 204 countries (1990-2021), we analyzed age-standardized mortality rates (ASMR) and disability-adjusted life years (DALY) for PMP-attributable LRIs, stratified by Socio-demographic Index (SDI), pollution source, and demographics. …"

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

"…</p>Methods<p>To investigate the role of the endolysosomal two-pore channel 2 (TPC2) in HCC, we employed genetic and pharmacological approaches, including TPC2 knockout (KO) and pharmacological inhibition using SG094. …"

Statistical data. حسب Bo Yang (104813)

"…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …"

Sensitivity of land types to threat factors. حسب Bo Yang (104813)

"…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …"

DataSheet1_Updated evidence of the Naoshuantong capsule against ischemic stroke: a systematic review and meta-analysis of randomized controlled trials.docx حسب Cuilin Que (19743256)

"…Background<p>Stroke is a serious health issue that can result in death or disability, leading to a significant economic strain on society and families. …"

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx حسب Ruochen Zhang (3434996)

"…In order to compare N/P efficiency more intuitively, we combined N/P content, N/P uptake, N/P uptake efficiency and N/P recover efficiency to calculate N/P comprehensive efficiency.…"

Data Sheet 1_Comparison of adverse events between intensity-modulated radiation therapy and tomotherapy for early stage breast cancer: a retrospective cohort study.pdf حسب Yan Xia (534241)

"…</p>Conclusions<p>Compared with IMRT, TOMO decreases the incidence of radiation pneumonitis but fails to improve acute skin toxicity. …"

Supplementary Material for: Minimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney... حسب Neves P.D.M.M. (20408168)

"…The kidney is a frequent target of SARS-CoV-2, potentially developing lesions in glomeruli, vessels, and tubulointerstitium in response to this infection. Herein we present the analysis of the first large Latin American cohort of adult patients undergoing kidney biopsy due to COVID-19-associated kidney disorders. …"

Table 1_Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort.docx حسب Mary Ngongang Kameni (20924126)

"…Our most significant findings include the association of double mutant alleles (AA) of rs4646140 and rs2074192 in the ace2 gene with decreased IL-6 and IL-2 expression levels respectively in TB-COVID-19 participants. …"

PDLB - Balance Sheet حسب Nguyen Linh (19516642)

"…</p><p><br></p><p dir="ltr">ECIP capital: PDLB received $225M of ECIP capital, and the regulators assigned them the lowest possible dividend (0.5%) on this capital for the first year of payments (announced in June). If we assume PDLB continues to pay 0.5% on this preferred and they have a cost of preferred equity of 10%, then we can calculate the value of this $225M liability as just $11M, with the rest a write-up to equity.…"

DataSheet1_The β2-adrenergic biased agonist nebivolol inhibits the development of Th17 and the response of memory Th17 cells in an NF-κB-dependent manner.docx حسب Mehri Hajiaghayi (19822665)

"…</p>Results<p>Nebivolol treatment decreased IL-17A and IFN-γ secretion by activated memory Th cells and elevated IL-4 levels. …"

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” حسب Chanping You (9067448)

"…</p><p><br></p><p dir="ltr">This study investigated the role of AR in chemotherapy response using two AR-positive breast cancer cell lines. We assessed responses to multiple chemotherapeutic agents—palbociclib, docetaxel, doxorubicin, paclitaxel, and cisplatin. …"

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity حسب Mengyu Liu (2890397)

"…<p>Trimethyltin chloride (TMT) is widely used as a constituent of fungicides and plastic stabilizers in the industrial and agricultural fields, and is generally acknowledged to have potent neurotoxicity, especially in the hippocampus; however, the mechanism of induction of neurotoxicity by TMT remains elusive. Herein, we exposed Neuro-2a cells to different concentrations of TMT (2, 4, and 8 μM) for 24 h. …"

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. حسب DIMITRIOS KIMOGLOU (20499350)

"…<br>Chronic stress disrupts the apoptotic process and contributes to<br>tumorigenesis. In particular, we seek to illustrate the epigenetic influence of stress on genes that control apoptosis, as well as the significance of the HPA axis as a therapeutic target for restoring cellular equilibrium. …"

Table 5_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 1_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 4_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 6_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"

Table 3_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx حسب Jichao Li (1973251)

"…As the NDF/NFC ratios increased, total gas production decreased linearly. The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …"