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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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mediated defense » mediated gene (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
mediate decrease » mean decrease (Expand Search)
mediated defense » mediated gene (Expand Search)
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Depletion of Sec10 promotes the expression of IFN-I and inflammatory cytokines.
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Sec10 blocks the JAK-STAT pathway by downregulating the expression of STAT1.
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Table 1_Interactions between particulate matter and bacteria during cowshed PM2.5-induced respiratory injury initiates GBP2/Caspase-11/NLRP3-mediated intracellular bacterial defens...
Published 2025“…Furthermore, PM<sub>2.5</sub> particles significantly enhanced bacterial intracellular invasion, initiated the guanylate-binding protein 2 (GBP2)-mediated intracellular bacterial defense mechanism, further triggered the non-canonical NLRP3 pathway, and ultimately induced a cascade of inflammatory responses and pyroptosis. …”