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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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18061
Table 1_DNase I alleviates renal inflammatory injury in MRL/lpr mice by inhibiting NETs formation.docx
Published 2025“…Furthermore, the critical molecules PADI4, HMGB1, TLR4, and MYD88 were significantly upregulated in peripheral blood neutrophils from LN patients, and their expression levels in the kidneys of MRL/lpr mice increased in a time-dependent manner.…”
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18062
Image 2_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg
Published 2025“…</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”
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18063
Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of...
Published 2025“…</p>Results<p>The number of IHD deaths and DALYs resulting from non-optimal temperature experienced a rise of 71.6% and 60.6%, respectively. And it showed regional imbalances: in the region with low-middle socio-demographic index (SDI), it was increased [EAPC for ASMR: 0.39% (95% CI: 0.2%, 0.58%), EAPC for ASDR: 0.33% (95% CI: 0.15%, 0.52%)], while decreased in the high SDI region, [EAPC for ASMR: −3.44% (95%CI: −3.58%, −3.3%), EAPC for ASDR: −3.18% (95%CI: −3.32%, −3.03%)]. …”
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18064
Image 1_Tanyu Tongzhi Formula relieves the progression of atherosclerotic plaque through lipid regulation and anti-inflammatory effects.jpeg
Published 2025“…Objective<p>Tanyu Tongzhi Formula (TTF), a clinically proven empirical prescription, has been utilized to treat atherosclerosis (AS) for decades. …”
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18065
Image 1_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg
Published 2025“…</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …”
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18066
Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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18067
Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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18068
Table 5_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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18069
Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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18070
Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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18071
Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx
Published 2025“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4<sup>+</sup>CD38<sup>+</sup>T%, CD8<sup>+</sup>CD38<sup>+</sup>T%, CD155<sup>+</sup>T%, CD4<sup>+</sup>TeM<sup>+</sup>T%, CD8<sup>+</sup>TIGIT<sup>+</sup>T%, and M-MDSC, and decreased CD4<sup>+</sup>LAG3<sup>+</sup>T%, CD4<sup>+</sup>TN<sup>+</sup>T%, and Th17 cells. …”
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18072
Dataset and R code for Humann-Guilleminot et al. - Dose-dependent effects of cadmium on food consumption, mass, and bioaccumulation in the moth <i>Spodoptera littoralis.</i>
Published 2025“…Our results show that sublethal doses of cadmium have a significant effect on food consumption and relative larval growth rate over a 6-day period, and to a lesser extent, affect larval mass at higher doses. …”
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18073
Multivariate statistical analysis diagram.
Published 2025“…<p><b>(a, b)</b> PLS-DA diagrams. The separation pattern was satisfactory, with significant differences in principal components among the groups, indicating that the metabolic profiles underwent significant alterations between different groups. …”
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18074
Effects of repeated intravenous esketamine administration on affective biases
Published 2025“…Misclassifications of other emotions as sad also decreased (<i>p</i> = .035, d = −0.79), indicating a reduced response bias towards sadness. …”
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18075
Supplementary file 1_Roles of oral anticoagulant use on the risk of 28-day mortality and in-hospital mortality in patients with acute respiratory distress syndrome.docx
Published 2025“…After adjusting for the respective confounding factors, the associations of Warfarin with decreased risk of 28-day and in-hospital mortality were not significant (P > 0.05).…”
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18076
Table 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.docx
Published 2025“…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …”
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18077
The analgesic effect of total saponins of Tribulus terrestris on neuropathic pain was studied based on TLR4/NF-κB pathway
Published 2025“…ELISA was employed to detect levels of IL-1β, IL-6, and TNF-ɑ in spinal cord. CCI significantly decreased PMWT and TL. …”
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18078
Image 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.tif
Published 2025“…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …”
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18079
Baumer-TPW_2023_Dopamine-Monocytes_PMID37251548.xlsx
Published 2025“…Indicative of D2-signaling, cAMP levels were found to be lower in DA-treated monocytes compared to</p><p dir="ltr">untreated controls (control 29.78 pmol/ml vs DA 22.97 pmol/ml; p =0.038) and the impact of DA on NCM CCR2</p><p dir="ltr">expression was abrogated by co-treatment with 8-CPT, a cAMP analog. Furthermore, Filamin A (FLNA), a</p><p dir="ltr">prominent actin-crosslinking protein, that is known to regulate CCR2 recycling, significantly decreased in DA-</p><p dir="ltr">treated NCM (p < 0.05), indicating a reduction of CCR2 recycling. …”
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18080
Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx
Published 2025“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”