Differential expression patterns and functional gene groups associated with SARS-CoV-2 viral load across serially collected samples. by Vasanthi Avadhanula (259546)

UpSet plot summarising key differentially expressed gene trends and Gene ontology analysis of differentially expressed genes present only in extremely high viral load group. by Vasanthi Avadhanula (259546)

S1 File - by Vasanthi Avadhanula (259546)

“…The human nose organoid-generated host transcriptional response captured many aspects of responses observed in the above patient samples, while suggesting the existence of distinct host responses to SARS-CoV-2 depending on the cellular context, involving both epithelial and cellular immune responses. Our findings provide a catalog of SARS-CoV-2 host response genes changing over time and magnitude of these host responses were significantly correlated to viral load.…”

Demographic characteristics of the matched groups with good quality RNA sequencing data. by Vasanthi Avadhanula (259546)

Flow Chart of Study Participant Selection. by Zhi Jin (3742471)

“…Notably, individuals with long sleep duration (>9 hours) had a significantly decreased risk of CVD (OR: 0.36, 95% CI: 0.15–0.85, P = 0.02) compared to those with shorter sleep durations.…”

Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…After 3 weeks, intramuscular Bet1L siRNA injection significantly increased the number of denervated NMJs in the injected muscle. …”

Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…After 3 weeks, intramuscular Bet1L siRNA injection significantly increased the number of denervated NMJs in the injected muscle. …”

Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues. by Erienne G. Norton (9612079)

“…Two-tailed Student <i>t</i> test (<b>A</b>–<b>D</b>, <b>F</b>–<b>I</b>) or Benjamini–Hochberg test (<b>E</b>); NS, not significant. …”

Event-free survival analysis of microvascular outcome. by Clemens Plattner (21567706)

Event-free survival analysis of macrovascular outcome. by Clemens Plattner (21567706)

Structure-Affinity-Pharmacokinetics Relationships of Novel ¹⁸F‑Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging by Yui Ishizaka (19922137)

“…In particular, BTF showed high and selective binding affinity for OX1R. In a biodistribution study using normal mice, [¹⁸F]­BTF exhibited brain uptake, and radioactivity in the brain was significantly decreased by preinjection of unlabeled BTF. …”

Vps34 orchestrates transcriptional and epigenetic remodeling events corresponding to terminal eTreg differentiation during perinatal life. by Erienne G. Norton (9612079)

“…AP-1-related transcription factors with predicted decreased activity are labeled. See also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.s016" target="_blank">S8 Table</a>. …”

Growth of Sf14 in various media. by Nykki D. Ross (20933968)

Growth of bacteria in various media and temperatures with or without Sf14 infection. by Nykki D. Ross (20933968)

Expression of the major capsid protein <i>gp34</i> gene in nutrient-poor (M9) or -rich (LB) conditions at various temperatures. by Nykki D. Ross (20933968)

Insulin-free survival in patients with and without FHD. by Clemens Plattner (21567706)

Proteomic and Transcriptomic Profiling Revealed Vital Molecular Events in the Transition from Goat Colostrum to Mature Milk by Xiao Zhang (152326)

“…Our results indicate that the milk protein changes were associated with a network of mammary gene expression changes; importantly, the prime factors include enhanced mammary growth/development, decreased protein translation, attenuated protein folding, and lower lip/carbohydrate metabolism. …”

Heterogeneity analysis. by Ying Zhao (16546)

“…Instrumental variables (IVs) were identified as genome-wide significant single-nucleotide polymorphisms (SNPs) with a significance threshold of <i>P </i>< 1 × 10⁻⁸ and an independence criterion of <i>r</i>² < 0.001. …”

Reverse MR analysis data. by Ying Zhao (16546)

“…Instrumental variables (IVs) were identified as genome-wide significant single-nucleotide polymorphisms (SNPs) with a significance threshold of <i>P </i>< 1 × 10⁻⁸ and an independence criterion of <i>r</i>² < 0.001. …”

SNP dressing by screening. by Ying Zhao (16546)

“…Instrumental variables (IVs) were identified as genome-wide significant single-nucleotide polymorphisms (SNPs) with a significance threshold of <i>P </i>< 1 × 10⁻⁸ and an independence criterion of <i>r</i>² < 0.001. …”