DataSheet1_Biomarkers of response to ocrelizumab in relapsing–remitting multiple sclerosis.pdf by Fernando Rodríguez-Jorge (17279800)

“…Decrease in sGFAP values occurred later in both groups, with significant reductions observed at 12 months for INFL and 6 and 12 months for NEDA-3. …”

DataSheet1_Biomarkers of response to ocrelizumab in relapsing–remitting multiple sclerosis.pdf by Fernando Rodríguez-Jorge (17279800)

“…Decrease in sGFAP values occurred later in both groups, with significant reductions observed at 12 months for INFL and 6 and 12 months for NEDA-3. …”

PVD neurons show reduced lysosome function during aging and in the <i>hlh-30</i> mutant. by Ruiling Zhong (22339779)

“…<b>(G)</b> The amount of degradative cargo SNT-1 in individual lysosomal compartments shows a bimodal distribution. Threshold = 529 AU. <b>(H)</b> Aging, chronic concanamycin A exposure, and the <i><i>hlh-30</i></i> mutant each result in an increased portion of lysosomal compartments with an atypically high amount of SNT-1::GFP. ** <i>P</i> < 0.01, * <i>P</i> < 0.05, pairwise comparisons not labeled show no significant difference, Fisher’s exact test with Holm correction. …”

Table 1_Multi-omics revealed that the postbiotic of hawthorn-probiotic alleviated constipation caused by loperamide in elderly mice.pdf by Yu Wei (365236)

“…Network pharmacology identified 20 cross-targets of FS in constipation. RT-qPCR showed decreased NR1I2 and SULT1A1 and increased GLP-2r in FS-treated mice. …”

Secondary and tertiary outcomes. by Maram Khaled (14642937)

“…Primary outcome is pain intensity with movement (elicited by asking the patient to move from supine to sitting position) using 0–10 Numerical Rating Scale (0 = no pain, 10 = worst possible pain).</p><p>Significance</p><p>The results of this study may result in improved pain control, maternal satisfaction and wound healing; decrease the use of perioperative opioids; potentially decrease the incidence of postpartum depression and persistent pain; and overall lead to better postoperative outcomes thereby decreasing healthcare costs.…”

CONSORT flow diagram. by Maram Khaled (14642937)

“…Primary outcome is pain intensity with movement (elicited by asking the patient to move from supine to sitting position) using 0–10 Numerical Rating Scale (0 = no pain, 10 = worst possible pain).</p><p>Significance</p><p>The results of this study may result in improved pain control, maternal satisfaction and wound healing; decrease the use of perioperative opioids; potentially decrease the incidence of postpartum depression and persistent pain; and overall lead to better postoperative outcomes thereby decreasing healthcare costs.…”

Table 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

“…Cornuside (CNS), a bioactive iridoid glycoside derived from Cornus officinalis (Sieb. et Zucc.), has garnered increasing attention for its bone-protective, neuroprotective, anti-inflammatory, and anti-diabetic properties, yet its effects on ALI remain unclear.…”

Table 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.xlsx by Tong Luo (458639)

“…Cornuside (CNS), a bioactive iridoid glycoside derived from Cornus officinalis (Sieb. et Zucc.), has garnered increasing attention for its bone-protective, neuroprotective, anti-inflammatory, and anti-diabetic properties, yet its effects on ALI remain unclear.…”

DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”

The Impact of Mindfulness-Based Intervention on Reducing Aggressive Behaviour and Promoting Student Wellbeing in Sports by Moruf Adebayo Abidogun (13491958)

“…The data collected from the self-developed questionnaire are analyzed using descriptive statistics to calculate mean and standard deviations, and analysis of covariance to compare pre and post-intervention scores between the experimental and control groups. The results indicate a significant reduction in aggressive behaviour among the experimental group compared to the control group, with a marked decrease in verbal and physical aggression. …”

Image1_Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury.tif by Tomoyuki Nakagiri (3765511)

“…Introduction<p>Pulmonary ischemia-reperfusion (IR) injury (IRI) plays a significant role in various lung disorders and is a key factor in the development of primary graft dysfunction following lung transplantation. …”

Data Sheet 1_Longitudinal changes in bodyweight, body condition, and muscle condition in ageing pet cats: findings from the Cat Prospective Ageing and Welfare Study.docx by Christine R. Pye (22118977)

“…All three metrics showed significant non-linear associations with age. Bodyweight increased slightly from age 7 to 10 (estimated marginal mean 4.77–4.82 kg) before decreasing to 4.30 kg by age 16 years. …”

Presentation 1_Global patterns of change in the burden of malnutrition in older adults from 1990 to 2021 and the forecast for the next 25 years.pdf by Le Li (356426)

“…Background<p>Malnutrition poses a significant public health challenge, particularly as the global population ages. …”

Data Sheet 1_Phenotypic adaptation and genomic variation of Kandelia obovata associated with its northern introduction along southeastern coast of China.docx by Jiaqi Zhang (412762)

“…Subsequent whole-genome re-sequencing have unveiled a significant decrease in genetic diversity within the northernmost population, suggesting that temperature plays a primary role in shaping genetic variability within the K. obovata species.…”

Table 1_Phenotypic adaptation and genomic variation of Kandelia obovata associated with its northern introduction along southeastern coast of China.xlsx by Jiaqi Zhang (412762)

“…Subsequent whole-genome re-sequencing have unveiled a significant decrease in genetic diversity within the northernmost population, suggesting that temperature plays a primary role in shaping genetic variability within the K. obovata species.…”

DataSheet1_The gut microbiota changed by ketogenic diets contribute to glucose intolerance rather than lipid accumulation.docx by Wei Li (7081)

“…Here, we found that two types of KDs, KD1 (8.8% carbohydrate, 73.4% fat, 17.9% protein, 5.7 kcal/g) and KD2 (0.4% carbohydrate, 93.2% fat, 6.4% protein, 6.7 kcal/g), induced changes of gut microbiota and its metabolites, contributing to glucose intolerance but not lipid accumulation in mice. Following a 2-week intervention with KDs, mice fed on KD1 displayed symptoms related to obesity, whereas KD2-fed mice exhibited a decrease in body weight but had severe hepatic lipid accumulation and abnormal fatty acid metabolism, while both KDs led to significant glucose intolerance. …”

Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx by Yihan Sun (3432287)

“…No significant increase in adverse drug events (ADEs) was observed (RR = 1.32, 95% CI 0.58–2.96). …”

Data Sheet 1_Past and future trends in swiss snow cover: multi-decades analysis using the snow observation from space algorithm.docx by Charlotte Poussin (20718146)

“…The pixel-wise analysis reveals significant negative trends in the monthly NDSI across all seasons, with the most pronounced decreases at low to mid-elevations, particularly in winter and spring (e.g., a 50% reduction in NDSI for pixels showing positive significative trends in winter below 1,000 m, and a 43% reduction in spring between 1,000 and 2,000 m). …”

<b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b... by Weidong Qian (20813608)

“…The results demonstrated that IBC (4 μg/mL) significantly reduced the minimum inhibitory concentration (MIC) of AmB from 1 μg/mL to 0.25 μg/mL, indicating a fourfold increase in potency. …”

Supplementary file 1_Past and future trends in swiss snow cover: multi-decades analysis using the snow observation from space algorithm.docx by Charlotte Poussin (20718146)

“…The pixel-wise analysis reveals significant negative trends in the monthly NDSI across all seasons, with the most pronounced decreases at low to mid-elevations, particularly in winter and spring (e.g., a 50% reduction in NDSI for pixels showing positive significative trends in winter below 1,000 m, and a 43% reduction in spring between 1,000 and 2,000 m). …”