Supplementary Material for: ACOT4 and ACOT6 activate Akt-mTOR pathway and inhibit calcium oxalate-induced renal tubular cell injury by figshare admin karger (2628495)

“…Introduction: Kidney stones caused by calcium oxalate (CaOx) is a chronic kidney disease. Acyl coenzyme A thioesterases (ACOTs) serve as the key regulators of fatty acids metabolism. …”

Table 1_Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inhibiti... by Biao Lei (3763393)

“…Meanwhile, JYGBF inhibited the formation of neutrophil extracellular traps (NETs) in lungs, which is characterized by the production of ROS, peptidyl arginine deiminase 4 (PAD4), citrullinated histone H3 (CitH3), myeloperoxidase (MPO), neutrophil elastase (NE), S100A8/A9 and MPO-CitH3 colocalization. Moreover, JYGBF decreased platelet counts and the expression of its activated markers (CD62P and αIIbβ3) accompanied by the drop of fibrinogen (FIB) and fibrin degradation product (FDP), accounting for alleviating hypercoagulable state. …”

Data Sheet 1_Jing-Yin-Gu-Biao formula protects mice from postinfluenza Staphylococcus aureus infection by ameliorating acute lung injury and improving hypercoagulable state via inh... by Biao Lei (3763393)

“…Meanwhile, JYGBF inhibited the formation of neutrophil extracellular traps (NETs) in lungs, which is characterized by the production of ROS, peptidyl arginine deiminase 4 (PAD4), citrullinated histone H3 (CitH3), myeloperoxidase (MPO), neutrophil elastase (NE), S100A8/A9 and MPO-CitH3 colocalization. Moreover, JYGBF decreased platelet counts and the expression of its activated markers (CD62P and αIIbβ3) accompanied by the drop of fibrinogen (FIB) and fibrin degradation product (FDP), accounting for alleviating hypercoagulable state. …”

Table 5_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx by Chuanchuan Wang (12228518)

“…Linkage disequilibrium analysis showed that 2 SNPs of SPP1 (g. 36,700,265 C > T and g. 36,693,596 C > A) constituted a haplotype that correlated with milk protein percentage, and the dominant haplotype was H2H2, which was CCTT. 4 SNPs of NCAPG (g. 37,342,705 C > A, g. 37,343,379 G > T, g. 37,374,314 C > A and g. 37,377,857 G > A) constituted a haplotype associated with milk protein percentage, 305-days milk protein yield and 305 days milk yield. …”

Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma by Zelei Yang (18491142)

“…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …”

Land Use Change Transfer Diagram. by Wanzhuang Huang (17357306)

“…The impact of road network density and river network density on the evolution of production-living-ecological land conflicts in the Shiyang River Basin was the most significant. The optimization results of national spatial patterns and regulation strategies could provide a scientific basis for the optimization and comprehensive management of national spatial planning in arid inland river basins.…”

Table 2_Untargeted metabolic analysis in serum samples reveals metabolic signature in children with congenital heart failure on enalapril therapy.csv by N. J. L. Smeets (21188726)

“…Patients were defined as responder when aldosterone levels decreased after a single administration of enalapril. …”

Table 1_Untargeted metabolic analysis in serum samples reveals metabolic signature in children with congenital heart failure on enalapril therapy.csv by N. J. L. Smeets (21188726)

“…Patients were defined as responder when aldosterone levels decreased after a single administration of enalapril. …”

Research framework. by Wanzhuang Huang (17357306)

“…The impact of road network density and river network density on the evolution of production-living-ecological land conflicts in the Shiyang River Basin was the most significant. The optimization results of national spatial patterns and regulation strategies could provide a scientific basis for the optimization and comprehensive management of national spatial planning in arid inland river basins.…”

Matched data. by Feng Zhang (6548)

“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”

Phage–antibiotic interactions are determined by the antibiotic, not the phage. by Yuval Mulla (12734528)

“…<p>(<b>a)</b> Growth curves of bacteria and phages (Bas04) in the presence of doxycycline (left) and nitrofurantoin (right). …”

Nomogram model. by Feng Zhang (6548)

“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”

Data Sheet 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.zip by Chengcheng Yu (6663170)

“…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …”

Table 1_The prevalence and correlates of falls in adults with attention-deficit/hyperactivity disorder: cross-sectional study.docx by Maraheb M. Alkhalidi (22389535)

“…Background<p>Falls are a major concern due to potentially causing injuries and long-term disabilities. …”

Table 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.docx by Chengcheng Yu (6663170)

“…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …”

XRD diffraction pattern spectra of PFAgNPs. by Kenedy Kiyimba (9942393)

“…The no observed adverse effect level was 50 mg/kgBW, the lowest observed adverse effect level was 100 mg/kgBW, and median lethal dose (LD₅₀) was 1000 mg/kg. The PFAgNPs significantly decreased (<i>P</i> < 0.05) serum proteins, cholesterol, estrogen and progesterone alongside preservation of the histoarchitecture of the uterus. …”

Data Sheet 2_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf by Cara J. Westmark (9302270)

“…Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …”

Flowchart of Study Design and Analysis. by Feng Zhang (6548)

“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”

Data Sheet 1_Modified ZhuJing pill protects retinal pigment epithelium against oxidative stress-induced epithelial–mesenchymal transition through Nrf2-mediated Akt/GSK3β pathway.do... by Ning Yang (114965)

“…Notably, the EMT-suppressing effect of mZJP was significantly attenuated upon Nrf2 silencing, as evidenced by enhanced cell migration, decreased epithelial marker expression (E-cadherin), increased mesenchymal marker expression (vimentin and α-SMA), suppression of the Nrf2 pathway, and activation of the Akt/GSK3β pathway.…”

Multivariate Binary Logistic Regression Analysis. by Feng Zhang (6548)

“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”