Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf حسب Faruk Hossen (20275670)

"…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …"

Data Sheet 2_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx حسب Stephanie Dauth (13274397)

"…Significant between-group differences were observed for changes in some parameters at day 4 (e.g., IL-10) and day 14. …"

Data Sheet 1_Effect of thyme-ivy syrup on antiviral immune response in patients with mild COVID-19: a prospective, open-label, randomized pilot study.docx حسب Stephanie Dauth (13274397)

"…Significant between-group differences were observed for changes in some parameters at day 4 (e.g., IL-10) and day 14. …"

Behavioral characterization of prenatal nicotine exposure (PNE) and control mice. حسب Rodrigo Vidal (4177060)

"…Quantification of the average total distance traveled. Significant differences were observed between PNE animals and control mice (PNE: 78.37 ± 2.01 m; n = 6; Control = 51.57 ± 3.33 m; n = 6), t = 6,883 df = 10, p < 0,0001. …"

The effect of inulin treatment on plasma untargeted metabolomic profiles in mice of diverse groups. حسب Ke Li (106849)

"…Color key in the heat map represents the metabolite expression value: red represents the significant increases and blue stands for the remarkable decreases. …"

Image 1_The impact of informal caregiving on the mental health of health care workers during the COVID-19 pandemic—cross-sectional and longitudinal results from the VOICE study.jpe... حسب Gloria-Beatrice Wintermann (462596)

"…IC emerged as a significant risk factor for increased psychological distress longitudinally, even after controlling for confounders. …"

Supplementary file 1_The impact of informal caregiving on the mental health of health care workers during the COVID-19 pandemic—cross-sectional and longitudinal results from the VO... حسب Gloria-Beatrice Wintermann (462596)

"…IC emerged as a significant risk factor for increased psychological distress longitudinally, even after controlling for confounders. …"

Image 3_The impact of informal caregiving on the mental health of health care workers during the COVID-19 pandemic—cross-sectional and longitudinal results from the VOICE study.jpe... حسب Gloria-Beatrice Wintermann (462596)

"…IC emerged as a significant risk factor for increased psychological distress longitudinally, even after controlling for confounders. …"

Image 2_The impact of informal caregiving on the mental health of health care workers during the COVID-19 pandemic—cross-sectional and longitudinal results from the VOICE study.jpe... حسب Gloria-Beatrice Wintermann (462596)

"…IC emerged as a significant risk factor for increased psychological distress longitudinally, even after controlling for confounders. …"

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx حسب Aaron D. Schwab (18289974)

"…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …"

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg حسب Aaron D. Schwab (18289974)

"…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …"

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx حسب Aaron D. Schwab (18289974)

"…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …"

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx حسب Aaron D. Schwab (18289974)

"…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …"

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg حسب Aaron D. Schwab (18289974)

"…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …"

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg حسب Aaron D. Schwab (18289974)

"…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …"

Effect of inhibitors upon muscarine-induced constriction of tracheal segments. حسب Innokentij Jurastow (22430601)

"…Among the tested substances, 8-sPT, apamin and Rp-cAMP significantly increased muscarine-induced contraction, while U-73122 inhibited muscarine responses.…"

U-shaped association between serum calcium and all-cause mortality in coronary heart disease with chronic kidney disease: evidence from two cohort studies in China and the United S... حسب Shuling Su (21730297)

"…In EGHDCP-CHD cohort, Cox regression models demonstrated that subjects in the lowest or the highest serum calcium group had a significantly higher risk of mortality. Besides, both cohorts showed similar inflection points in the threshold analysis. …"

Data Sheet 1_Global, regional, and national burden and trends of reproductive-aged male and female infertility from 1990–2021.docx حسب Guoqiang Zeng (6315596)

"…</p>Conclusion<p>Overall, the burden of infertility among 15–49 years men and women has significantly increased globally over the past 32 years, particularly in middle SDI regions and among the 35–39 age group. …"

Data Sheet 2_Global, regional, and national burden and trends of reproductive-aged male and female infertility from 1990–2021.xlsx حسب Guoqiang Zeng (6315596)

"…</p>Conclusion<p>Overall, the burden of infertility among 15–49 years men and women has significantly increased globally over the past 32 years, particularly in middle SDI regions and among the 35–39 age group. …"

Supplementary file 1_Electroacupuncture pretreatment ameliorates anesthesia and surgery-induced cognitive dysfunction in aged rats: insights from gut microbiota modulation.xlsx حسب Huajuan Lei (22753547)

"…However, at 3- and 4-weeks post-surgery, the EA group exhibited significantly reduced latency and increased crossing times compared to the MD and JE groups. …"