Table 3_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 1_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 1_Efficacy of the early start Denver model combined with the TEACCH program in children with autism spectrum disorder.docx حسب Ling-Ling Ma (7894544)

"…</p>Results<p>Both groups showed significant within-group improvement after intervention, but the combined observation group demonstrated greater gains. …"

The role of IRF-1 in mediating T-cell immune imbalance in systemic lupus erythematosus and the construction of a diagnostic model حسب Zichen Huang (6587885)

"…<p>Systemic lupus erythematosus (SLE), characterized by immune dysregulation, urgently requires improved diagnostic tools and mechanistic insights. …"

Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv حسب Zhenyu Zhao (737165)

"…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"

Supplementary file 1_The efficacy and safety of endoscopic surgery combined with platelet-rich plasma for lumbar disk herniation: a systematic review and meta-analysis.pdf حسب Guimei Guo (4127074)

"…For back pain, VAS scores decreased significantly at 3 months (MD = −0.58, 95% CI: −0.84 to −0.31, p < 0.0001), 6 months (MD = −0.32, 95% CI: −0.48 to −0.16, p = 0.0001), ≥12 months (MD = −0.40, 95% CI: −0.51 to −0.28, p < 0.00001) and at last follow-up (MD = −0.23, 95% CI: −0.36 to −0.10, p = 0.0005; very low certainty). …"

Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx حسب Alexandra Prodea (22617710)

"…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …"

Data Sheet 1_Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study.pdf حسب Marcos Maldonado-Díaz (11221102)

"…</p>Results<p>Patients showed a small numerical increase, without reaching statistical significance in task difficulty progression (p = 0.016), lower limb endurance (p = 0.016), and single-leg support time (p = 0.031). …"

Data Sheet 1_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.pdf حسب Alexandra Prodea (22617710)

"…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …"

Relations between action changes post-exposure and pre-exposure behaviors and motives for participants of Experiment 4. حسب Claire Lugrin (21156528)

"…These effects are however small, showing that the changes in prosocial action are mostly independent of the aggregate prosocial action or judgments pre-exposure. …"

Supplementary file 1_The impact of SGLT2 inhibitors on cardiac remodeling after myocardial infarction: an updated meta-analysis of randomized controlled trials.zip حسب Ma Li Xu (21163796)

"…Treatment with SGLT2i + GDMT led to a significantly higher improvement in the LVEF ≤40% group than in the LVEF >40% group (MD = 5.20, 95% CI 2.74 to 7.66; p < 0.0001). …"

Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx حسب Chunyu Yao (13559263)

"…Concurrently, hepatic Cocs2/3 and Cish gene expression was downregulated, attenuating their inhibitory effects on hormonal and glucagon signaling, thereby improving glucose and lipid metabolism. Metabolomic profiling further indicated that HM018 significantly altered bile acid composition by modulating gut microbiota-mediated bile acid metabolism. …"

Data Sheet 1_Aloe-emodin plus TIENAM ameliorate cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating microbiota.docx حسب Jingqian Su (666622)

"…Moreover, substantial improvements in survival rates of AE + TIE-treated mice (10% to 60%) within 168 h were observed relative to the CLP group. …"

Data Sheet 1_Microbial network-driven remediation of saline-alkali soils by salt-tolerant plants.docx حسب Yushuang Cui (2265055)

"…The results indicated that the planting of TC, TA, and HM effectively reduced soil electrical conductivity (EC) by 82.9, 88.3, and 86.2%, respectively. TC and TA significantly decreased the pH from 8.79 to 8.35 and 8.06, respectively, (p < 0.05). …"

Data Sheet 1_From psychological wellbeing to distress: the role of psychological counseling interventions in university students.pdf حسب Francesco Craig (8214780)

"…Post-intervention, psychological distress decreased significantly (p < 0.001), with 56.7% of students falling over the clinical distress cut-off at T1 compared to 84.4% at T0. …"

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx حسب Long Wu (655081)

"…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …"

Table 1_Burden of heart failure attributable to chronic kidney disease in older adults (1990–2021): an analysis from the global burden of disease study.docx حسب Wenli Liu (400084)

"…Socioeconomic disparities were decreased but persisted. From 1990 to 2021, the inequality slope index for prevalence decreased from 143.66 (95% CI, 167.68–119.65) to 114.12 (95% CI, 151.59–76.65), whereas the health inequality concentration index improved from −0.21 (95% CI, −0.30 to −0.12) to −0.07 (95% CI, −0.14 to 0) for prevalence.…"

Table 4_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx حسب Long Wu (655081)

"…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …"