بدائل البحث:
significant barriers » significant barrier (توسيع البحث), significant factors (توسيع البحث), significant burden (توسيع البحث)
barriers decrease » larger decrease (توسيع البحث), barrier disease (توسيع البحث)
teer decrease » mean decrease (توسيع البحث), greater decrease (توسيع البحث)
_ decrease » _ decreased (توسيع البحث), _ decreasing (توسيع البحث)
significant barriers » significant barrier (توسيع البحث), significant factors (توسيع البحث), significant burden (توسيع البحث)
barriers decrease » larger decrease (توسيع البحث), barrier disease (توسيع البحث)
teer decrease » mean decrease (توسيع البحث), greater decrease (توسيع البحث)
_ decrease » _ decreased (توسيع البحث), _ decreasing (توسيع البحث)
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
منشور في 2025"…Introduction<p>The potential for drug-induced gastrointestinal (GI) toxicity is significant, since the GI tract is one of the first barriers which come in to contact with oral drugs. …"
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Raw data of Figs 1–6 in this study.
منشور في 2025"…When gut epithelial PGAM5 receptor and apoptosis were inhibited by PGAM5-specific siRNA, inhibitor (LFHP-1c) and apoptosis inhibitor (Z-VAD-FMK), trans-epithelial electrical resistance (TEER) and TJs expression were obviously increased, and intestinal permeability was evidently decreased. …"
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S1 File -
منشور في 2024"…Compared with LPS treatment alone, BA significantly mitigated the reduction in the TEER, decreased FD-4 flux permeability, increased the mRNA expression of ZO-1 and Occludin, and normalized the distribution of ZO-1 and Occludin in Caco2 cells. …"
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Experimental treatments and groups.
منشور في 2024"…Compared with LPS treatment alone, BA significantly mitigated the reduction in the TEER, decreased FD-4 flux permeability, increased the mRNA expression of ZO-1 and Occludin, and normalized the distribution of ZO-1 and Occludin in Caco2 cells. …"
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Primers for RT-qPCR.
منشور في 2024"…Compared with LPS treatment alone, BA significantly mitigated the reduction in the TEER, decreased FD-4 flux permeability, increased the mRNA expression of ZO-1 and Occludin, and normalized the distribution of ZO-1 and Occludin in Caco2 cells. …"
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Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf
منشور في 2025"…Additionally, the Cyn intervention group showed significant improvements in both the intestinal barrier structure (elevated tight junction protein levels and proper localization) and function (reduced serum FD4 levels, increased intestinal TEER, and decreased bacterial translocation rates in mesenteric lymph nodes [MLNs] and livers). …"