Data Sheet 1_Metastatic organ count stratifies survival in immunotherapy-treated metastatic colorectal cancer: a retrospective cohort study.docx by Hai-Yan Fu (1586935)

“…</p>Conclusions<p>Increased metastatic organ count in patients with mCRC was associated with decreased immunotherapy ORR and worse prognosis, with a particularly pronounced effect observed in patients with lung metastasis.…”

Image 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.jpeg by Kexin Xu (757891)

“…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…”

Table 1_Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study.docx by Xinping Yu (555177)

“…The OR of developing migraine was 0.97 (95% CI: 0.94–0.98) in individuals with selenium intake ≥101.9 ug/day in adults with 20–50 years.</p>Conclusion<p>A higher dietary selenium intake is significantly associated with a decreased prevalence of migraine, and age can modify the association between them. …”

Data Sheet 1_Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis.pdf by Takuya Murao (114383)

“…In vitro, OP18 reduced the production of the inflammatory cytokine TNF-α in DAMP-activated macrophages and restored mitochondrial function, as evidenced by improved oxygen consumption rate (OCR) and ATP production. In a lethal sepsis model induced by cecal ligation and puncture (CLP), DAMP levels were significantly elevated, while OP18 treatment markedly reduced the serum DAMP levels. …”

Image 1_Interaction between dietary selenium intake and age on severe headache or migraine in the United States: a population-based study.pdf by Xinping Yu (555177)

“…The OR of developing migraine was 0.97 (95% CI: 0.94–0.98) in individuals with selenium intake ≥101.9 ug/day in adults with 20–50 years.</p>Conclusion<p>A higher dietary selenium intake is significantly associated with a decreased prevalence of migraine, and age can modify the association between them. …”

Table 2_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx by Lisheng Xiao (15919517)

“…<p>Klebsiella pneumoniae infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. …”

Table 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx by Lisheng Xiao (15919517)

“…<p>Klebsiella pneumoniae infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. …”

Supplementary file 1_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Background and objective<p>Pulmonary sarcoidosis is a chronic respiratory disease with a growing global burden. …”

Supplementary file 4_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Background and objective<p>Pulmonary sarcoidosis is a chronic respiratory disease with a growing global burden. …”

Table 1_Mental symptoms in post-COVID syndrome and post-COVID-19 vaccination syndrome: results of a representative population survey.docx by Andreas Czaplicki (21978866)

“…The prevalence of self-reported PCVS was 12.6% among vaccinated individuals, with no significant gender differences, but fewer cognitive symptoms in older adults. …”

Supplementary file 2_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Background and objective<p>Pulmonary sarcoidosis is a chronic respiratory disease with a growing global burden. …”

A well-resolved phylogeny of <i>Epilobium</i> (Onagraceae) taxa in the British Isles finds no correlation between genomic divergence and the outcome of hybridisation by Kaitlin Saward (22126620)

“…</p> <p>We did not detect a significant relationship between parental divergence and hybridisation likelihood and/or hybrid fertility in <i>Epilobium</i> sect. …”

Supplementary file 3_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Background and objective<p>Pulmonary sarcoidosis is a chronic respiratory disease with a growing global burden. …”

Data_Sheet_1_Joint association of serum sodium and frailty with mild cognitive impairment among hospitalized older adults with chronic diseases: a cross-sectional study.docx by Zhaozhao Hui (10221125)

“…</p>Conclusion<p>Both lower and higher serum sodium impose a significantly higher risk for MCI in older adults with frailty. …”

Table 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.xlsx by Jing Wang (6206297)

“…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.…”

Table_1_Biological characterization and in vitro fungicide screening of a new causal agent of walnut leaf spot in Guizhou Province, China.DOCX by Xianxi Ao (19822227)

“…Increasing the light period significantly decreased conidia production and conidia germination. …”

Table1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.XLSX by Cong Zhang (582922)

“…However, Crohn’s disease (CD) (OR = 1.023, 95% CI = 0.993-1.055, p = 0.134) did not show a causal association with the risk of AP. Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

Image 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif by Jing Wang (6206297)

“…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.…”

Table1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.XLSX by Cong Zhang (582922)

“…However, Crohn’s disease (CD) (OR = 1.023, 95% CI = 0.993-1.055, p = 0.134) did not show a causal association with the risk of AP. Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif by Jing Wang (6206297)

“…Functionally, knocking down ACTR6 inhibited cell migration and proliferation, produced a G1 cell cycle arrest, and decreased the viability of liver cancer cells.…”