Gene set enrichment analysis (GSEA) of the DEGs. حسب Wei He (131453)

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ALKL1196M –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

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Identification of DEGs and DESRGs of AD in the GSE52093 dataset. حسب Wei He (131453)

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ALK^wt–ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

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ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. حسب Richard Junior Zapata Dongo (17912565)

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Comparative Analysis of Hela Cells Cultured under Static Conditions and Exposed to Fluid Shear Stress. حسب Xinyao Zhao (5824427)

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Visualization of immune cell infiltration between AD and control group. حسب Wei He (131453)

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BCL2 protein keeps their expression in different conditions treatment nevertheless each EML4-ALK cell modells exhibit variable expression. حسب Richard Junior Zapata Dongo (17912565)

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Combination therapy exhibited apoptosis in Ba/F3 EML4-ALKmutant cell models. حسب Richard Junior Zapata Dongo (17912565)

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miR-1247-3p was downregulated in CRC resistant cells. حسب Dequan Wang (6007007)

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The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. حسب Richard Junior Zapata Dongo (17912565)

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Downregulation of miR-1247-3p inhibited apoptosis and reduced chemosensitivity in cells. حسب Dequan Wang (6007007)

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Loewe synergy-antagonism score analysis shows additive and synergistic effects after ALKi and ABT-199 combination treatment. حسب Richard Junior Zapata Dongo (17912565)

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miR-1247-3p was downregulated in tissues of patients with CRC and was associated with prognosis and drug resistance. حسب Dequan Wang (6007007)

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Causal relationships between allergic diseases and significant declines in lung function: a multivariable Mendelian randomization study حسب Jiannan Lin (6954983)

"…However, in multivariable MR analysis, the independent effects of atopic dermatitis and allergic conjunctivitis on lung function were no longer significant. Only allergic asthma continued to show a significant causal relationship with decreased lung function (OR [95%CI]: 1.019 [1.008–1.030], <i>p</i> < .001).…"

Overexpression of miR-1247-3p promoted apoptosis and inhibited resistance in drug-resistant cells. حسب Dequan Wang (6007007)

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Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

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BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK^mutants. حسب Richard Junior Zapata Dongo (17912565)

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Ba/F3 EML4-ALK^mutants exhibit variable dose-response to ABT-199 treatment. حسب Richard Junior Zapata Dongo (17912565)

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Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

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