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8281
Data Sheet 7_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Serum IL-6 protein expression levels were significantly elevated in patients with gouty arthritis (GA) compared to healthy individuals, with multifactor logistic regression revealing an odds ratio (OR) of 2.175 for IL-6. …”
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8282
Data Sheet 4_The role and impact of the IL-6 mediated JAK2-STAT1/3 signaling pathway in the pathogenesis of gout.zip
Published 2025“…Serum IL-6 protein expression levels were significantly elevated in patients with gouty arthritis (GA) compared to healthy individuals, with multifactor logistic regression revealing an odds ratio (OR) of 2.175 for IL-6. …”
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8283
Table 1_Altered Th17/Treg balance and therapeutic targeting of RORγ in primary focal hyperhidrosis.docx
Published 2025“…Elevated IL-17 and IL-6 and reduced IL-10 and TGF-β1 levels were observed in PFH serum. Sweat glands showed increased RORγt and decreased FOXP3 expression. …”
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8284
Paiva et al. data
Published 2024“…Specifically, haemoglobin concentration decreased 24 hours after ozone therapy, MCHC levels increased seven days post-ozone therapy, and serum AST activity decreased seven days post-ozone therapy. …”
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8285
<b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>
Published 2025“…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …”
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8286
<b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>Item
Published 2025“…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …”
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8287
Cholecalciferol alleviates testicular dysfunction in experimental hyperthyroidism via antioxidant, anti-inflammatory and antiapoptotic effects
Published 2025“…It significantly decreased the levels of serum inflammatory markers and malondialdehyde levels. …”
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8288
Supplementary Material for: The role of neutrophils in venous thrombosis in primary membranous nephropathy
Published 2025“…In animal experiments, the plasma cfDNA levels elevated significantly after IVC stenosis in PHN rats, and GSK484 decreased the plasma cfDNA levels in PHN rats with IVC stenosis. 4 hours after IVC stenosis surgery, thrombi formed in PHN rats were both longer and heavier compared to those observed in control rats, and GSK484 administration significantly inhibits the thrombus formation in PHN rats. …”
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8289
Protective role of <i>N</i>-acetyl-l-tryptophan against hepatic ischemia-reperfusion injury via the RIP2/caspase-1/IL-1β signaling pathway
Published 2024“…The mRNA and protein expression levels of serine-threonine kinase 2 (RIP2) and interleukin-1β (IL-1β) were significantly increased in the I/R and H<sub>2</sub>O<sub>2</sub> groups when compared with the controls; however, these levels were significantly decreased after l-NAT intervention. …”
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8290
Discriminating wake vs. NREM sleep from individual spike train measures.
Published 2025“…MSTMs are ordered according to decreasing decoding accuracy. Gray dotted lines indicate significance thresholds, with darker shades of gray indicating more stringent significance levels. …”
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8291
The effects of CHRM2 knockdown on osteogenic differentiation and cell proliferation.
Published 2025“…(B) The RT-qPCR results showed that the expression of CHRM2 in cells with Si-CHRM2 knockdown decreased significantly. (C) The cell proliferation were measured by OD value at 450 nm, and the observation time points were at 0, 24, 48, 72 and 96 hours. …”
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8292
Image 1_Enhancement of host defense against Helicobacter pylori infection through modulation of the gastrointestinal microenvironment by Lactiplantibacillus plantarum Lp05.tif
Published 2025“…Lp05 treatment significantly modified the intestinal and gastric microbiota, increasing beneficial bacteria like Lactobacillus and Ligilactobacillus, and decreasing harmful bacteria such as Olsenella, linked to pathological conditions.…”
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8293
Image 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.jpeg
Published 2025“…Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”
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8294
Clinical observation and immune effect of high-intensity focused ultrasound (HIFU) treatment on patients with colorectal cancer liver metastasis
Published 2025“…Post-treatment serum IL-6 levels decreased significantly (<i>p</i> < 0.001). …”
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8295
Data Sheet 1_Modulation of TLR7, TYK2 and OAS1 expression during SARS-CoV-2 infection.pdf
Published 2025“…</p>Results<p>TLR7 levels were higher in patients with mild disease compared to those with moderate disease and decreased over time. …”
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8296
Table 3_Tick HRF-dependent ferroptosis pathway to promote tick acquisition of Babesia microti.xlsx
Published 2025“…The midgut divalent iron (p<0.01) and reactive oxygen species (ROS) (p<0.05) levels were significantly elevated in infected ticks, and transmission electron microscopy (TEM) showed that mitochondrial ridges were absent or decreased in size. …”
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8297
Table 1_Tick HRF-dependent ferroptosis pathway to promote tick acquisition of Babesia microti.docx
Published 2025“…The midgut divalent iron (p<0.01) and reactive oxygen species (ROS) (p<0.05) levels were significantly elevated in infected ticks, and transmission electron microscopy (TEM) showed that mitochondrial ridges were absent or decreased in size. …”
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8298
Table 2_Tick HRF-dependent ferroptosis pathway to promote tick acquisition of Babesia microti.docx
Published 2025“…The midgut divalent iron (p<0.01) and reactive oxygen species (ROS) (p<0.05) levels were significantly elevated in infected ticks, and transmission electron microscopy (TEM) showed that mitochondrial ridges were absent or decreased in size. …”
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8299
Data Sheet 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.zip
Published 2025“…Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”
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8300
Trimester-specific thyroid function markers and gestational diabetes risk: evidence from a tertile-based cohort of euthyroid pregnancies
Published 2025“…TSH levels increased, while fT3 and fT4 levels decreased significantly across trimesters (<i>p</i> < 0.001). …”