Data_Sheet_1_Altered topological properties of functional brain networks in patients with first episode, late-life depression before and after antidepressant treatment.docx حسب Chaomeng Liu (14721880)

"…However, the information transmission efficiency and centrality of some brain regions continue to decline over time, perhaps related to their progressive cognitive impairment.</p>…"

Image_3_Genetic Association of rs1021188 and DNA Methylation Signatures of TNFSF11 in the Risk of Conductive Hearing Loss.TIF حسب Amal Bouzid (12425760)

"…Moreover, 26 loci in the TNFSF11 gene were in linkage disequilibrium with rs1021188, revealing relative similarities between different populations. Significant differences in both DNA methylation and unmethylation status were detected with 4.53- and 4.83-fold decreases in the global DNA methylation levels in female and male OTSC groups, respectively. …"

Image_2_Genetic Association of rs1021188 and DNA Methylation Signatures of TNFSF11 in the Risk of Conductive Hearing Loss.TIF حسب Amal Bouzid (12425760)

"…Moreover, 26 loci in the TNFSF11 gene were in linkage disequilibrium with rs1021188, revealing relative similarities between different populations. Significant differences in both DNA methylation and unmethylation status were detected with 4.53- and 4.83-fold decreases in the global DNA methylation levels in female and male OTSC groups, respectively. …"

Image_1_Seizures regulate the cation-Cl− cotransporter NKCC1 in a hamster model of epilepsy: implications for GABA neurotransmission.JPEG حسب Juan-Manuel Bonet-Fernández (16415964)

"…Mounting evidence suggests that the impairment of GABAergic inhibitory neurotransmission plays a crucial role in the pathophysiology of epilepsy, both in patients and animal models. …"

Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx حسب Wenyue Hu (799025)

"…Meanwhile, the addition of QG to the diet increased the mRNA expressions of Nrf2 and TFR1, showing no significant difference from those of the control group. …"

Image_1_Genetic Association of rs1021188 and DNA Methylation Signatures of TNFSF11 in the Risk of Conductive Hearing Loss.TIF حسب Amal Bouzid (12425760)

"…Moreover, 26 loci in the TNFSF11 gene were in linkage disequilibrium with rs1021188, revealing relative similarities between different populations. Significant differences in both DNA methylation and unmethylation status were detected with 4.53- and 4.83-fold decreases in the global DNA methylation levels in female and male OTSC groups, respectively. …"

Data_Sheet_1_Early Brassica Crops Responses to Salinity Stress: A Comparative Analysis Between Chinese Cabbage, White Cabbage, and Kale.xlsx حسب Iva Pavlović (6579485)

"…In parallel with the photosynthetic impairments, the Na⁺/K⁺ ratio was highest in Chinese cabbage leaves and lowest in kale leaves while kale root is able to keep high Na⁺/K⁺ ratio without a significant increase in MDA. …"

Image_1_Seizures regulate the cation-Cl− cotransporter NKCC1 in a hamster model of epilepsy: implications for GABA neurotransmission.JPEG حسب Juan-Manuel Bonet-Fernández (16415964)

"…Mounting evidence suggests that the impairment of GABAergic inhibitory neurotransmission plays a crucial role in the pathophysiology of epilepsy, both in patients and animal models. …"

DataSheet1_Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor.docx حسب Daniel Hunziker (2673724)

"…Taken together, these results provide evidence that the dysregulation of the ATX-LPA axis in the aqueous humor of glaucoma patients, in addition to the postulated outflow impairment, might also contribute to RGC loss. The observation that ATX-inhibitor treatment in both glaucoma models did not result in significant IOP increases or decreases after oral treatment indicates that protection from RGC loss due to inhibition of the ATX-LPA axis is independent of an IOP lowering effect.…"

DataSheet1_Molecular dynamics study of tropical calcific pancreatitis (TCP) associated calcium-sensing receptor single nucleotide variation.docx حسب Ashish Shrivastava (5325164)

"…The results of molecular dynamic simulations showed that the mutations P163R, I427S, D433H, and V477A caused conformational changes and decreased the stability of protein structures. This study also demonstrates the significance of TCP associated mutations. …"

Table_1_NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway.pdf حسب Na Liu (102929)

"…Compared with NADPH, the combination showed more significant neuroprotective effects, presenting more neurons survive and better motor function recovery. …"

Image_2_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... حسب Lautaro Francisco Belfiori (17901602)

"…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …"

Image_1_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... حسب Lautaro Francisco Belfiori (17901602)

"…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …"

Table_1_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... حسب Lautaro Francisco Belfiori (17901602)

"…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …"

Table_2_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... حسب Lautaro Francisco Belfiori (17901602)

"…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …"

DataSheet1_Quanduzhong capsules for the treatment of grade 1 hypertension patients with low-to-moderate risk: A multicenter, randomized, double-blind, placebo-controlled clinical t... حسب Xuan Xu (781842)

"…After 4 weeks of treatment, there were no significant differences between the groups in terms of safety indicators (p > .05). …"

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” حسب Chanping You (9067448)

"…For palbociclib, a CDK4/6 inhibitor, AR activation induced RB1 polyubiquitination and degradation, diminishing RB1 levels—a key downstream target of CDK4/6—and thus impairing palbociclib efficacy. Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …"

Image2_Exome sequencing confirms the clinical diagnosis of both joubert syndrome and klinefelter syndrome with keratoconus in a han Chinese family.JPEG حسب Xinhe Fang (9281324)

"…Keratoconus (KC) is a kind of genetically predisposed eye disease that causes blindness characterized by a dilated thinning of the central or paracentral cornea conically projected forward, highly irregular astigmatism, and severe visual impairment. Klinefelter syndrome is caused by an extra X chromosome in the cells of male patients, and the main phenotype is tall stature and dysplasia with secondary sex characteristics. …"

Image1_Exome sequencing confirms the clinical diagnosis of both joubert syndrome and klinefelter syndrome with keratoconus in a han Chinese family.JPEG حسب Xinhe Fang (9281324)

"…Keratoconus (KC) is a kind of genetically predisposed eye disease that causes blindness characterized by a dilated thinning of the central or paracentral cornea conically projected forward, highly irregular astigmatism, and severe visual impairment. Klinefelter syndrome is caused by an extra X chromosome in the cells of male patients, and the main phenotype is tall stature and dysplasia with secondary sex characteristics. …"

Ciliary pattern of paramecia depleted for TZ proteins. حسب Delphine Gogendeau (8566902)

"…DNAH2^RNAi cells present a percentage of short cilia slightly higher than the controls. Impairing ciliary beating of TMEM216^RNAi cells by DNAH2 decreases this percentage. …"