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significantly greater » significantly correlated (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
larger decrease » marked decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
increase » increased (Expand Search)
significantly greater » significantly correlated (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
larger decrease » marked decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
increase » increased (Expand Search)
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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Analyses excluding participants with BMI 25 kg/m<sup>2</sup> or greater from healthy volunteer groups.
Published 2024“…Similarly to the original analyses in the full data set (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002936#pbio.3002936.g001" target="_blank">Fig 1F</a>), there was a significant post-conditioning increase in preference among participants with low preference at baseline (t<sub>(23)</sub> = 2.7; <i>P</i> = 0.01; <i>n</i> = 24) but not in those with higher baseline preference (t<sub>(19)</sub> = 0.05; <i>P</i> = 0.96; <i>n</i> = 20). …”
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