Search alternatives:
significant effects » significant effect (Expand Search), significantly affected (Expand Search)
effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
teer decrease » greater decrease (Expand Search)
significant effects » significant effect (Expand Search), significantly affected (Expand Search)
effects decrease » effects decreased (Expand Search), effects regress (Expand Search)
teer decrease » greater decrease (Expand Search)
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Amino acids interactions and binding energy describe that ABT-199 binds to ALK<sup>Mutant</sup>.
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Ba/F3 EML4-ALK<sup>mutants</sup> exhibit variable dose-response to ABT-199 treatment.
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…In parallel the cell viability was determined after 24 h to be able to distinguish between an unspecific cytotoxic effect or direct tight junction damage. Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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