Interannual variations. by John P. Ryan (7388621)

“…Solid black triangles along the bottom indicate significant increase (years 3,4) or decrease (year 5) in daily unique humpback whale IDs relative to the previous year (p < 0.05; one-sided Wilcoxon rank sum tests). …”

AgTL2 embryos have altered lipids, metabolites, and transcriptional profiles during development. by Maurice A. Itoe (9930475)

“…(C) Heatmap of metabolites analyzed by LC-MS showing levels of the 60 most highly dysregulated metabolites in AgTL2 embryos compared to controls throughout development (values of <i>t</i> test statistic, range: blue to red = significant decrease to increase) (3 biological replicates represented by triplicate columns at each time point). …”

Data Sheet 1_16S rRNA and metabolomics reveal the key microbes and key metabolites that regulate diarrhea in Holstein male calves.docx by P. P. Cao (20565548)

“…Introduction<p>Diarrhea is a prevalent disease among calves, which significantly hinders their growth and development, thereby impacting farm productivity and revenue. …”

Data Sheet 2_16S rRNA and metabolomics reveal the key microbes and key metabolites that regulate diarrhea in Holstein male calves.xls by P. P. Cao (20565548)

“…Introduction<p>Diarrhea is a prevalent disease among calves, which significantly hinders their growth and development, thereby impacting farm productivity and revenue. …”

Data Sheet 1_N6-methyladenosine RNA landscape in the aged mouse hearts.zip by Xia Jing (3255219)

“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”

Data Sheet 2_N6-methyladenosine RNA landscape in the aged mouse hearts.zip by Xia Jing (3255219)

“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”

Data Sheet 3_N6-methyladenosine RNA landscape in the aged mouse hearts.zip by Xia Jing (3255219)

“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”

Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf by Xia Jing (3255219)

“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H₂O₂-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”

Data Sheet 1_Perceived protective behavioral changes in Chinese residents post-dynamic zero-COVID policy lifting: a cross-sectional study.docx by Yuan-Yuan Song (6287387)

“…The mean scores for the two vaccination-related items were significantly greater than the hypothesized no-change value of 2 (p < 0.001). …”

PRISMAS flowchart of the screening process. by Xianghong Hu (17966261)

“…</p><p>Conclusions</p><p>The available evidence indicates that preoperative PENG block can significantly decrease opioid consumption and pain early after hip surgery, and it may also promote early functional rehabilitation. …”

Image_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.JPEG by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Data Sheet 1_Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics.docx by Tao Jiang (28401)

“…</p>Results<p>ATM treatment (160 mg/kg) observably ameliorated insulin resistance (IR), hyperglycemia, hyperlipemia and pathological injury in the liver and pancreas. In addition, ATM significantly decreased the expression of TNF-α, IL-1β, IL-6, NF-κB and IL-17A, and significantly increased the level of IL-10 in diabetic mice. 16S rRNA sequencing and targeted GC-MS metabolomics result indicated that ATM restored gut microbiota dysbiosis based on increasing beneficial bacteria Lactobacillus and reducing pathogenic bacteria Helicobacter and Prevotella leading to the accumulation of propionic and valeric acids and the reduction of lipopolysaccharides (LPS) release, intestinal inflammation and intestinal barrier damage. …”

Table_1_Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level.DOCX by Reza Hakkak (11086)

“…HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p < 0.05) compared to the SPC-LIF group. …”

Data Sheet 1_Combination of Sodium Butyrate and Immunotherapy in Glioma: regulation of immunologically hot and cold tumors via gut microbiota and metabolites.docx by Sui Li (8872481)

“…Moreover, metabolites produced by the gut microbiota can significantly impact both systemic immune responses and central nervous system (CNS) immunity. …”

Assessment of calcium events, pERK levels, NMDA receptor expression and extracellular zinc levels in <i>slc13a5</i> mutants. by Deepika Dogra (21072023)

“…<i>5a</i>^{<i>−/−</i>}<i>;5b</i>^{<i>−/−</i>} larvae show a significant decrease in Palm-ZP1:CellMask Orange CTCF ratio in the plasma membrane compared to WTs. …”

Image 4_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…END was defined as a decrease of ≥2 points in the GCS score within 24 h of admission. …”

Table 2_Epidemiology of second trimester induced abortion in Ethiopia: a systematic review and meta-analysis.docx by Mesfin Abebe (12400154)

“…The findings highlight the urgent need for targeted interventions to address these factors and decrease the incidence of second-trimester abortions. …”

Image 6_Serum neuritin as a predictive biomarker of early neurological deterioration and poor prognosis after spontaneous intracerebral hemorrhage: a prospective cohort study.tif by Yanwen Xu (663813)

“…END was defined as a decrease of ≥2 points in the GCS score within 24 h of admission. …”

Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Routine blood tests revealed significantly elevated neutrophil granulocytes and monocytes, along with a marked decrease in lymphocytes. …”

Table 1_Unexpected estradiol decline during ovarian stimulation monitoring affects cumulative live birth.docx by Haixiao Chen (12565087)

“…In both unmatched and matched cohorts, the CLBRs were significantly decreased (unmatched cohort: 66.3% versus 55%, P<0.001, adjusted OR 0.83, 95% CI: 0.76,0.91; matched cohort: 59% versus 55%, P = 0.003, adjusted OR 0.84, 95%CI: 0.75,0.94). …”