Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx by Qingqing Zhuang (22109089)

“…Objective<p>To assess clinical outcomes in patients treated with eculizumab for acute attacks of aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (NMOSD).</p>Methods<p>We retrospectively analyzed prospectively collected data from the Huashan NMOSD registry cohort, and included patients who received eculizumab within 30 days of attack onset. …”

Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx by Nikola Habek (21178259)

“…Background<p>Preclinical and clinical research of insulin resistance and glucose homeostasis in metabolic disorders are essential. In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…”

Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx by Jian-Tong (21583487)

“…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”

Data Sheet 1_Enhancing tuber yield and nutraceutical quality of potato by supplementing sunlight with LED red-blue light.pdf by Antonio Pannico (4890952)

“…Introduction<p>We investigated the influence of genetic material and light spectrum on plant performance of two cultivars of potato (Solanum tuberosum L.), ‘Colomba’ and ‘Libra’, grown in greenhouse, in the view of future plant cultivation in Space and terrestrial vertical farming and controlled environment agriculture under limiting light conditions.…”

Table_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…The analysis included 25,178 American adults. We examined the association between the Composite Dietary Antioxidant Index (CDAI) and the prevalence of sleep disorders. …”

Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri... by Stephan R. Vavricka (8994197)

“…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …”

Data Sheet 1_A novel bivariate nomogram for predicting sequela vaginal lesions after surgery in patients with HPV-associated cervical cancer.docx by Yueheng Liu (9228588)

“…Then we built three predictive models; multiple logistic regression was optional, with its AUC at 0.7955 in the ROC curve.…”

Data Sheet 1_Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.csv by Farzana Gul (7119200)

“…Purpose<p>Fasting is known to have beneficial effects on human physiology and health due to changes in gut microbiota and its associated metabolites. We investigated the effects of intermittent and Ramadan fasting on the gut microbial composition, diversity, and short-chain fatty acid (SCFA) profile in a Pakistani population.…”

Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx by Naama Lax (20998004)

“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”

Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx by Chunmei Wu (3202050)

“…Objectives<p>To describe the real-world efficacy and safety of obinutuzumab in a heterogeneous systemic lupus erythematosus (SLE) population, including severe or refractory manifestations.</p>Methods<p>We retrospectively analyzed 56 SLE patients who received a single dose of obinutuzumab (1000 mg) at Renji Hospital, Shanghai Jiao Tong University School of Medicine between October 2021 and March 2024. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…The analysis included 25,178 American adults. We examined the association between the Composite Dietary Antioxidant Index (CDAI) and the prevalence of sleep disorders. …”

Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> by Meng-Ru Guo (21375491)

“…Using an iTRAQ-based proteomic strategy, we recognized Ribonuclease H2 subunit B (Rnh2B) as a target substrate for Cdc4. …”

The impact of chronic pain on the quality of life of patients attending soshanguve community health centre (CHC), Tshwane district, South Africa by Thanyani Pandelani (8218809)

“…<p dir="ltr">Background: Chronic pain poses a considerable challenge to individuals' well-being, leading to decreased quality of life, limitations in daily functioning, and a higher reliance on healthcare services, resulting in significant economic burdens. …”

Data Sheet 5_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Table 1_Filtered and unfiltered lipoaspirates reveal novel molecular insights and therapeutic potential for osteoarthritis treatment: a preclinical in vitro study.docx by Alissa Behn (20793590)

“…</p>Discussion<p>Here, we provide first insights into how autologous nanofat therapy may ameliorate OA by enhancing chondrocyte proliferation and synoviocyte migration while modulating inflammatory and pain-related factors. …”

Image 2_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff by Haoming Shen (3816988)

“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”

Data Sheet 4_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Data Sheet 2_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…</p>Methods<p>Here we present the results of our one-arm open-label pilot clinical study of our novel biologics, a DNA plasmid encoding SQSTM/p62, in 17 companion dogs suffering from OA. …”