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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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20681
Table 1_Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head nec...
Published 2025“…In vivo, SBD intervention significantly reduced bone structural damage and apoptosis, decreasing the rate of empty bone lacunae. …”
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20682
Image 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif
Published 2025“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”
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20683
Image 3_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif
Published 2025“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”
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20684
RipU<sup>K60</sup> impacts actin cytoskeleton organization at 48 hours post infiltration.
Published 2024“…(G,H) RipU<sup>K60</sup> significantly increased actin filament density (G), and decreased actin bundling (H) compared to controls at 48 hpi. …”
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20685
Data Sheet 1_Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway.csv
Published 2025“…Protein–protein interaction (PPI) analysis combined with molecular complex detection (MCODE) identified six hub genes, namely, Ddit3, Atf3, Sesn2, Trib3, Ppp1r15a, and Gadd45a. Spearman’s correlation analysis revealed a significant correlation between the hub genes and ferroptosis-related DEGs. …”
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20686
Data Sheet 1_Global impact of Occupational Noise-Induced Hearing Loss (ONIHL): trends, gender disparities, and future projections: 1990–2036.docx
Published 2025“…In 2021, the YLDs rate decreased as the Socio-Demographic Index (SDI) increased across 224 countries, indicating a concentration of the burden in countries with a medium SDI. …”
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20687
Table_1_Hyperthyroidism, hypothyroidism, thyroid stimulating hormone, and dementia risk: results from the NHANES 2011–2012 and Mendelian randomization analysis.DOCX
Published 2024“…</p>Conclusion<p>This study provides evidence of a nonlinear relationship between TSH and FT4 concentrations and cognitive function, with hyperthyroidism decreasing the risk of dementia and VaD, hypothyroidism increasing the risk of dementia and VaD, and elevated serum TSH concentrations increasing the risk of AD. …”
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20688
Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario
Published 2025“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”
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20689
miR-155 directly targets the 3′UTR of TRAF3 and STAT1.
Published 2025“…<p><b>(A)</b> The predicted target sites of miR-155 in TRAF3 and STAT1 3′UTRs, as well as the mutant forms with the potential miR-155 binding sites mutated. …”
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20690
DataSheet1_Network meta-analysis of integrated traditional Chinese and Western medicine in the treatment of Sjogren’s syndrome.pdf
Published 2024“…</p>Conclusion<p>TCM combined with CWM has a very significant effect on treating SS compared with CWM alone. …”
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20691
Data_Sheet_1_Depression and health literacy among adolescents and adults in Germany: findings from two representative samples.pdf
Published 2024“…Introduction<p>Depressive disorders constitute a significant public health challenge. Health literacy might be an important factor to consider in prevention strategies for depressive disorders, which is why this study aimed at exploring the association between depressive symptom levels and severity and health literacy, along with additional sociodemographic factors.…”
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20692
Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus
Published 2025“…</p> <p>Compared to the HC group, SLE patients exhibited a decline in both Lyn mRNA and protein expression in PBMCs, with significant downregulation in the high SLEDAI group versus the low SLEDAI group and a notable reduction in the LN group relative to the non-LN group. …”
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20693
Study of monopolar plate springback applying zoned multistage forming process
Published 2025“…The length and width of an MPP both exceed 150 mm, but the thickness of its raw material plate is less than 0.1 mm, posing a significant challenge to the uniformity of its thickness after forming. …”
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20694
Beyond species richness: grazing and fertilization shape temperate grassland stability through distinct stabilizing effects
Published 2025“…Alterations in land use, particularly grazing and fertilization, pose significant threats to the stability of grassland ecosystems. …”
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20695
Assessing the biochemical and genotoxic effects of low intensity 2.45GHz microwave exposure on <i>Arabidopsis thaliana</i> plants
Published 2024“…This study assessed the short-term impact of low-intensity 2.45 GHz exposure on young <i>Arabidopsis thaliana</i> plants. The plants underwent a 48-hour exposure to continuous wave 2.45 GHz microwaves at a power density of 1.0 ± 0.1 W m<sup>−2</sup>. …”
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20696
Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX
Published 2024“…</p>Conclusion<p>Our study explored a significant correlation between PHDI and biological aging, indicating that adherence to PHD may prevent biological aging.…”
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20697
DNA damage protecting effects of EAExCC.
Published 2025“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”
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20698
CLIC1 accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells by inhibiting the Nrf2/HO-1 signalling pathway.
Published 2025“…<p>(a-c) Activity of oxidative stress markers of SOD (a), CAT (b), and GSH-Px (c) was reduced following inhibition of the Nrf2/HO-1 signalling pathway. …”
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20699
Table 1_High-concentrate diet supplemented with hydrolysable tannin improves the slaughter performance, intestinal antioxidant ability and barrier function of fattening lambs.docx
Published 2024“…Also, tannin supplementation significantly increased (p < 0.05) the level of jejunal and ileal total antioxidant capacity and reduced (p < 0.05) the jejunal malondialdehyde concentration in lambs. …”
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20700
Data Sheet 1_Improving tea quality and fruit yield through intercropping with climbing plants.pdf
Published 2025“…All intercropping treatments significantly increased tea leaf chlorophyll a, b, and total chlorophyll content compared with monoculture (CK), with maxima in PE-H (1.188, 0.447, and 1.635 mg/g) and SG-H (1.166, 0.425, and 1.591 mg/g), respectively. …”