First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Prilocaine-loaded silicone dressing with dual-functionality: integrated pain management and wound protection for burn care by Yanshu Lu (21987282)

“…The PET/CT results showed a significant decrease in pain indicators in the experimental group compared to the control group, confirming that the analgesic function of the dressing designed in this study is effective. …”

Data Sheet 1_Analysis between Helicobacter pylori infection and hepatobiliary diseases.docx by Zhenjun Yu (8205228)

“…Compared to the non-infection group, patients in the infection group exhibited a significant decrease in albumin levels and a notable increase in total cholesterol and erythrocyte sedimentation rate levels. …”

Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of <i>Mycobacterium abscessus</i> in macrophages by Ho Won Kim (18237328)

“…Mab infection shifted BMDMs towards a more energetic phenotype, marked by increased oxidative phosphorylation (OXPHOS) and glycolysis, with a significantly greater enhancement in OXPHOS. …”

Low-frequency dependence of HC context and EC object representations. by Pengcheng Lv (7609706)

“…<p><b>(A)</b> Removal of low-frequency (2–8 Hz) activity from the broadband activity significantly reduced HC context representation. …”

Table 1_Evaluation of the cardiorespiratory and antinociceptive effects of the total intravenous anesthesia technique with xylazine-butorphanol-propofol compared to isoflurane in c... by Shogo Sato (16544880)

“…Norepinephrine concentrations in both groups demonstrated a significant decrease from baseline values prior to the nociceptive stimuli; however, the difference disappeared during and before the stimulus. …”

The Plastic Footprint of the U.S. Agricultural System by Katie Malarkey (18020788)

“…Plastic use in food production is a complex part of this challenge: plastics can increase crop yields, extend growing seasons, and decrease manual labor, but their production, use, and waste leads to environmental and human health impacts. …”

DTG 3TC HIV EPI study.xlsx by Anna Esman (17983927)

“…Specifically, <i>CCR5</i> CpG 1 showed a significant increase in methylation from Week 0 to Week 48, while <i>CXCR4</i> CpG 3 displayed a significant decrease between Week 0 and Week 24. …”

S1 Raw data - by Yongle Du (3992198)

“…By integrating metabonomics with network pharmacology, we identified core targets of ZJP against myopia and constructed a compound-gene-disease-metabolite network. …”

Primer sequences for target genes. by Yongle Du (3992198)

“…By integrating metabonomics with network pharmacology, we identified core targets of ZJP against myopia and constructed a compound-gene-disease-metabolite network. …”

<b>Dependence of Low-frequency Plasmaspheric Hiss on Geomagnetic Activity and Solar Wind Dynamic Pressure and Its Electron Scattering Effects</b> by Shuqin Chen (22130011)

“…Using high-quality data from Van Allen Probe A between September 2012 and March 2019, we conduct a comprehensive statistical analysis of the global distribution of low-frequency hiss. …”

Metabolomic insights into the aging process of <i>Citrus reticulata</i> cv. ‘Dahongpao’ peel by Wenling Zhang (385480)

“…Comparative analysis showed a net decrease in volatiles from CR1 to CR2, but a significant net up-accumulation of diverse compounds from CR1 to CR3, and particularly from CR2 to CR3. …”

Supplementary file 1_Taxonomic and functional shifts in soil nematode communities following estuarine island reclamation.docx by Sufeng Pan (21460022)

“…We found a significant decrease in both taxonomic and functional diversity as tidal flats were converted to dry land, followed by a gradual recovery that progressed with increasing reclamation age. …”