Data Sheet 1_Enhancing AAV-microdystrophin gene therapy after repeat dosing by blocking phagocytosis.docx by Rita Spathis (187690)

“…</p>Results<p>Viral load was significantly increased by 77-fold in white blood cells after two rAAV9-microdystrophin doses compared to mice receiving a single dose. …”

Data Sheet 1_An in vitro evaluation of intravenous lipid emulsion on three common canine toxicants.docx by Emery Jones (19736377)

“…Samples were stored at −80°C prior to analysis.</p>Results<p>A significant decrease in total drug concentration was established for bromethalin and its metabolite desmethylbromethalin compared to positive controls. …”

Data Sheet 1_Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity.pdf by Ahmed Rakib (10876047)

“…This was associated with an increased infiltration of macrophages, CXCR3 expressing CD8 T cells, and monocytic myeloid-derived suppressor cells (M-MDSCs) with a concomitant decrease in numbers of dendritic cells (DCs), in the AT of siglec-E KO fed HFD versus the WT HFD counterparts. …”

Pediatric CPP with Praat and ADSV (Joshi et al., 2025) by Ashwini Joshi (21594817)

“…Age and <i>F</i>0 are significant predictors of CPP; however, the observed increase in CPP with increasing age in males is primarily due to the substantial decrease in <i>F</i>0 postpuberty. …”

Supplementary file 1_Global, regional, and national trends for childhood myocarditis from 1990 to 2021: health inequality and age-period-cohort analysis for the Global Burden of Di... by Hui-Juan Fang (22786595)

“…Health inequalities related to the sociodemographic index (SDI) and APC effect for CM burden were studied in this study.</p>Findings<p>A significant decreasing trend for ASR of incidence, prevalence, mortality, and DALYs from 1990 to 2021 was found for CM globally. …”

Data Sheet 1_Trends in nontraumatic subarachnoid hemorrhage-related mortality among young adult (15–64 years) population in the United States, 1999–2022.docx by Olivia Foley (20535083)

“…NSAH-related mortality decreased in all regions of the US between 1999 and 2022, while individual states demonstrated a variety of trends. …”

Table 1_Impacts of phosphate-solubilizing bacterium strain MWP-1 on vegetation growth, soil characteristics, and microbial communities in the Muli coal mining area, China.docx by Yanru Wu (2940186)

“…It caused a significant increase in the relative abundance of the genes regulating nitrogen fixation and nitrification in nitrogen cycling (p < 0.05), but a significant decrease in the genes regulating phospholipase (p < 0.05). …”

Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Meanwhile, compared to the groups treated with either IFNβ or RSL3 alone, the combination treatment of IFNβ and RSL3 significantly inhibited the growth of HT1080 three-dimensional (3D) spheroids and tumor in a mouse xenograft model.…”

Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Meanwhile, compared to the groups treated with either IFNβ or RSL3 alone, the combination treatment of IFNβ and RSL3 significantly inhibited the growth of HT1080 three-dimensional (3D) spheroids and tumor in a mouse xenograft model.…”

Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Meanwhile, compared to the groups treated with either IFNβ or RSL3 alone, the combination treatment of IFNβ and RSL3 significantly inhibited the growth of HT1080 three-dimensional (3D) spheroids and tumor in a mouse xenograft model.…”

Data Sheet 1_ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway.docx by Xiaofei Huang (2262337)

“…Moreover, it suppressed conventional CD4⁺CD25^- T cell proliferation in vitro in the absence of antigen-presenting cells (APCs), with an increase in IL-10 and decrease in IFN-γ production. On the other hand, it did not significantly alter DC maturation after allotransplantation.…”

Table 1_Associations between the Dietary Inflammatory Index and depression among pregnant and postpartum women: analysis of NHANES 2005–2018.docx by Jian Qiao (26659)

“…Diets with very high proinflammatory potential were linked to significantly increased odds of perinatal depression, whereas more anti-inflammatory diets did not result in a further decrease in depression risk below that threshold. …”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”

Image 1_Alpha oscillatory dysregulation: mapping EEG oscillatory in suicidal depression.tiff by Yue Zhao (186573)

“…</p>Results<p>EEG analysis showed a significant increase in alpha-band PSD and a significant decrease in FAA in DSI compared to DNSI (p < 0.05). …”

Table 1_Alpha oscillatory dysregulation: mapping EEG oscillatory in suicidal depression.docx by Yue Zhao (186573)

“…</p>Results<p>EEG analysis showed a significant increase in alpha-band PSD and a significant decrease in FAA in DSI compared to DNSI (p < 0.05). …”

DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP by Huadong Ke (19937268)

“…Furthermore, Berubicin exhibited a particularly high proportion of blood and lymphatic system disease AEs, reaching 45.6%, which was significantly greater than those observed for the other two drugs.…”

Comparison of average glutathione reductase. by Zohreh Ghotbeddin (20108032)

“…Glutathione reductase in the control group (p < 0.01), febrile group (p < 0.05), and DMI + febrile group (p < 0.05) showed a significant decrease at 45 days compared to 12 days. …”

Effect of NNK on 1p-Enh activity and CYP4B1 expression. by Li Dai (159381)

“…<b>(C)</b> Luciferase reporter assays showed a significant decrease in 1p-Enh activity in AC-16 and Beas-2B cells following exposure to NNK for 15 generations. …”

Analysis of transgenic Hp-FAR-2 expression on survival of male and female flies against <i>Streptococcus pneumoniae</i> infection. by Pakeeza Azizpor (14792401)

“…<b>B)</b> A significant decrease in 24-hour microbial load was observed in chromosome 3 UAS-Hp-FAR-2 male flies (TubP > Ch3-UAS) compared to the UAS control. …”

Data Sheet 1_Enabling immune checkpoint blockade efficacy in T-lymphopenia by restoring CD8 T cell dynamics with IL-7 cytokine therapy.docx by Yeon-Woo Kang (18285202)

“…Crucially, TLP led to a shift in the composition of tumor-infiltrating lymphocytes, with a decrease in PD-1⁺ tumor-reactive CD8 T cells and an increase in PD-1⁻ bystander cells. …”