Video 2_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

<i>Lefty1</i> and <i>Lefty2</i> are regulated by separate proximal enhancer regions in mouse embryonic stem cells. by Tiegh Taylor (5791382)

“…Deletion of the <i>Lefty1</i> enhancer leads to a significant reduction of <i>Lefty1</i> transcript abundance with a mild effect on <i>Pycr2</i>. …”

Data Sheet 1_Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy.pdf by Sindhuja Sivanandham (13851914)

“…</p>Results<p>Sphingomyelins (SM) and lactosylceramides (LCER) increased during acute infection, returning to baseline during chronic infection; Hexosylceramides (HCER) increased throughout infection, being normalized with prolonged ART; Phosphatidylinositols (PI) and lysophosphatidylcholines (LPC) decreased with SIV infection and did not return to normal with ART; Phosphatidylethanolamines (PE), lysophosphatidylethanolamines (LPE) and phosphatidylcholines (PC) were unchanged by SIV infection, yet significantly decreased throughout ART. …”

Method for establishing the multipath adaptive mitigation model considering deformation displacement of monitoring stations by Guo Zihuai (20442074)

“…The comparison between MAMM and the Multipath Hemispherical Model (MHM) indicates that, in the simulated displacement experiments, MHM’s effectiveness in mitigating multipath errors significantly decreases as the actual displacement distance increases, whereas MAMM consistently maintains an improvement rate in positioning precision of over 100%, markedly surpassing that of MHM. …”

Table 1_The impact of digital economy on the supply chain resilience of cross-border healthcare e-commerce.xlsx by Jianyu Liu (313522)

“…The results indicate that the digital economy significantly enhance supply chain resilience, with reduced reliance on foreign trade, increased export technology complexity, and decreased export concentration being key pathways for this improvement. …”

Chronic hyperpolarization of dFB^23E10Ո^84C10 neurons promotes sleep and impairs sleep homeostasis. by Joseph D. Jones (13883524)

“…A one-way ANOVA followed by Tukey’s multiple comparisons revealed that <i>dFB-Split>Kir2.1</i> female flies sleep significantly more than controls. …”

S1 File - by Qian Wang (32718)

“…Prior cancer history had little impact on DSS; however, the presence of prior solid cancer history, latency period of 10+ years, and prior administration of radiotherapy or chemotherapy significantly decreased OS. Prior cancer history had no effect on DSS, but survival compromised OS under specific circumstances.…”

Image 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.jpeg by Na Wang (193263)

“…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

Supplementary Material for: Additive inhibition of HERG channels expressed in Xenopus oocytes by antipsychotic drugs and citrus juice flavonoid naringenin by Yang K.-H.S. (18331101)

“…This additive HERG inhibition could pose an increased risk of arrhythmias by decreasing repolarization reserve and possible repolarization heterogeneity.…”

<b>Gene x environment interactions as drivers of lifespan variation in nematodes</b> by Justin Havird (2812975)

“…Both the genetic strains and phytochemicals were associated with mitochondrial function. We found significant effects of genetic background (although not always as precited from previous studies), chemical treatment, and their interactions (GxE) that explained variation in lifespan. …”

Image 1_STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit.tiff by Mohammad Jodeiri Farshbaf (20466956)

“…Introduction<p>Diabetes is a metabolic disorder of glucose homeostasis that is a significant risk factor for neurodegenerative diseases, such as Alzheimer’s disease, as well as mood disorders, which often precede neurodegenerative conditions. …”

Supplementary file 1_Toxicity evaluation of laser-synthesized pro-angiogenic carbon monoxide-rich gold nanoparticles in vitro and in vivo.docx by Thais Braga Gomes Araujo (22686905)

“…However, reduced glutathione levels decreased significantly in the brain at concentrations between 10 and 35 μg.L⁻¹, likely due to the interaction with the metallic surface of the nanoparticles, while in the liver they increased significantly following exposure to COR-AuNPs at concentrations between 20 and 75 μg.L⁻¹. …”

Supplementary file 1_Lurasidone induces developmental toxicity and behavioral impairments in zebrafish embryos.docx by Wentian Li (28857)

“…</p>Results<p>Lurasidone induced dose-dependent developmental toxicity, including reduced survival and hatching rates, decreased body length, and increased pericardial and yolk sac edema. …”

Data Sheet 1_HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1.pdf by Keita Tanigaki (13162449)

“…In HAX1-knockdown IHGE cells, significantly decreased levels of JAM1 were found. Additionally, cisplatin, a chemotherapeutic agent reported to inhibit HAX1, also led to decreased expression of both HAX1 and JAM1. …”

Conditional Knockout of Serine Racemase in Microglia Alleviates Alzheimer -like Pathology and Behavior by Reducing Neuroinflammation through Enhancing Histone Lactylation by shengzhou Wu (22341388)

“…Further, addition of C646, a p300 inhibitor or oxamate, an inhibitor of lactate dehydrogenase A, significantly reversed arginase1 or interleukin-10 mRNA levels in srr-/- microglia. …”

Data Sheet 1_Thermophilic microbial agents promote the fermentation progression of spent mushroom compost and pig manure.docx by Hongbo Du (1270113)

“…<p>Livestock and poultry manure, as a significant organic resource, had an enormous annual production but a utilization rate of less than 50%. …”

Data Sheet 1_Factors influencing the length of hospital stay of people experiencing homelessness.docx by Renate Karpenko (20858510)

“…</p>Conclusion<p>Gender had no significant effect on the LOS. The significant demographic factor was the duration of homelessness, indicating that the health status of PEH deteriorates and access to healthcare decreases over time. …”

Data for: Soil microplastics pollution can reduce viral abundance and have less consistent impacts on bacteria by Wen-Wen Huang (22122439)

“…In a microbial community experiment, soils with natural microbes in pots planted with maize were given PE or PVC contamination with a gradient of dosage. …”

Data Sheet 1_Ningxiang pigderived Enterococcus hirae regulates the inflammatory function and enhances the protection of piglets against ETEC challenge.docx by Longlin Zhang (9956945)

“…Additionally, ETEC infection significantly increased the spleen index and the expression of inflammatory cytokines in the spleen, serum and intestine, with decreasing serum sIgA and colonic SCFAs of piglets. …”

Table 1_Research on the changes in the disease burden of nasopharyngeal carcinoma caused by global occupational formaldehyde exposure from 1990 to 2021 and prediction of future tre... by Tingting Duan (5181482)

“…</p>Conclusions<p>From 1990 to 2021, the disease burden of NPC caused by global occupational formaldehyde exposure showed a downward trend, and the regional burden decreased with the increase of SDI.…”