Table 5_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…However, its anti-inflammatory role in vascular calcification is unclear.</p>Object<p>We investigated the efficacy of isowighteone in the treatment of vascular calcification, explored its potential mechanism, and determined whether isowighteone is a safe and effective treatment.…”

Table 6_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.docx by Yuanxi Mo (22090130)

“…However, its anti-inflammatory role in vascular calcification is unclear.</p>Object<p>We investigated the efficacy of isowighteone in the treatment of vascular calcification, explored its potential mechanism, and determined whether isowighteone is a safe and effective treatment.…”

Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…However, its anti-inflammatory role in vascular calcification is unclear.</p>Object<p>We investigated the efficacy of isowighteone in the treatment of vascular calcification, explored its potential mechanism, and determined whether isowighteone is a safe and effective treatment.…”

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 by Arijit Ghosh (1304952)

“…Altogether, we propose kininogen as a potential target for developing therapeutics for epilepsy intervention.…”

Table 1_Global, regional, and national burden of liver cancer in adolescents and young adults from 1990 to 2021: an analysis of the global burden of disease study 2021 and forecast... by Jingyu Wen (13913130)

“…</p>Interpretation<p>Despite a gradual decline in liver cancer burden among AYAs, NASH is emerging as a significant and rising cause of incidence and mortality. …”

Table1_Body composition and perceived stress levels in transgender individuals after one year of gender affirming hormone therapy.docx by Chiara Ceolin (19553155)

“…PSS and PHQ scores, initially higher in TGD individuals, did not change significantly after one year of GAHT. A significant correlation was found between body fat percentage and PHQ and PSS scores at baseline and one year after GAHT, respectively.…”

Table 1_From challenge to competence: the role of learning engagement in mediating stress and performance among clinical medical students in English-medium dental education.docx by Runheng Liu (5221034)

“…CMI) on medical students’ perceived academic stress, self-regulated learning engagement (SRLE) and academic performance in a dental course.</p>Materials and methods<p>A quasi-experimental design was employed with 123 undergraduate medical students enrolled in a stomatology course. …”

Data Sheet 1_Global burden and trends of viral hepatitis among women of childbearing age from 1990 to 2021.pdf by Shaojie Yang (722448)

“…Generally, the burden of viral hepatitis decreased with higher SDI levels, except for AHA. Between 1990 and 2021, the global age-standardized incidence rate for viral hepatitis among WCBA decreased annually by −1.11% for acute hepatitis A (AHA), −1.24% for AHB, and −0.18% for AHC, −0.34% for AHE, with more significant reductions observed for chronic hepatitis B (CHB) and CHC at −1.33% and −0.29%, respectively. …”

Data Sheet 1_Mycorrhizal extraradical mycelium can reduce cadmium uptake by maize and cadmium leaching from contaminated soil: based on an in-growth core experiment.docx by Yijie Yang (2804824)

“…Moreover, the rotation treatment significantly altered the Cd forms in the soil solution and leachate, increasing the proportion of free Cd²⁺ by 0.8–2.1% and decreasing the proportions of CdSO₄(aq) and CdOH⁺ by 6.1–56.1% and 26.1–48.7%, respectively. …”

Data Sheet 1_Characteristics of gut microbiota in Penaeus vannamei shifted with elevated salinity.docx by Bo Wang (86769)

“…The alpha diversity of the gut bacterial community of shrimp decreased with salinity. Significant differences in the composition and abundance of the core gut bacterial taxa were observed among ponds with varying salinity, and only 13 shared core operational taxonomic units (OTUs) were identified; the abundance of potential opportunistic pathogens decreased significantly in hypersaline environments. …”

Data Sheet 1_Real-time evaluation of antibacterial efficacy using bioluminescent assays for Pseudomonas aeruginosa and Staphylococcus aureus.pdf by Manali Patil (22142128)

“…Treatment with cefotaxime resulted in a significant reduction of the bioluminescent signal in P. aeruginosa compared to untreated controls, while doxycycline induced a delayed growth curve. …”

Table2_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.xlsx by Friederike Behler-Janbeck (3384488)

“…MicroCT scanning of femoral bones of Gpr41/43 dKO mice revealed a significant increase of trabecular bone volume and trabecular compared to WT controls. …”

Table_1_Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndr... by Zhixiao Xu (3469277)

“…</p>Results<p>After multivariable adjustment, individuals with elevated OBS were found to exhibit a decreased susceptibility to MetS [odds ratio (OR) 0.95; 95% CI 0.94-0.96]. …”

Table2_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.xlsx by Friederike Behler-Janbeck (3384488)

“…MicroCT scanning of femoral bones of Gpr41/43 dKO mice revealed a significant increase of trabecular bone volume and trabecular compared to WT controls. …”

DataSheet1_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.pdf by Friederike Behler-Janbeck (3384488)

“…MicroCT scanning of femoral bones of Gpr41/43 dKO mice revealed a significant increase of trabecular bone volume and trabecular compared to WT controls. …”

DataSheet1_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.pdf by Friederike Behler-Janbeck (3384488)

“…MicroCT scanning of femoral bones of Gpr41/43 dKO mice revealed a significant increase of trabecular bone volume and trabecular compared to WT controls. …”

Table1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.xlsx by Yunxia Zhang (30848)

“…Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. PKM1 inhibited MyHC1 and MyHC2a expression but promoted MyHC2b expression. …”

DataSheet2_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.pdf by Yunxia Zhang (30848)

“…Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. PKM1 inhibited MyHC1 and MyHC2a expression but promoted MyHC2b expression. …”

DataSheet1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.docx by Yunxia Zhang (30848)

“…Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. PKM1 inhibited MyHC1 and MyHC2a expression but promoted MyHC2b expression. …”

Supplementary Material for: Bidirectional Impact of Varying Severity of Acute Kidney Injury on Calcium Oxalate Stone Formation by Yang Y. (3237684)

“…We aimed to delineate the molecular interplay between AKI and nephrolithiasis. …”