A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

“…With average renal uptake of less than 10%ID/g, as opposed to 25%ID/g for [⁶⁸Ga]Ga-<b>PSMA-617</b>, this substantial decrease in renal accumulation translates to a significantly improved safety profile by minimizing nephrotoxic risks. …”

A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

“…With average renal uptake of less than 10%ID/g, as opposed to 25%ID/g for [⁶⁸Ga]Ga-<b>PSMA-617</b>, this substantial decrease in renal accumulation translates to a significantly improved safety profile by minimizing nephrotoxic risks. …”

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…When charging is completed, a distinct ion layering structure emerges. As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. …”

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…When charging is completed, a distinct ion layering structure emerges. As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. …”

Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…When charging is completed, a distinct ion layering structure emerges. As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. …”

A representative ultrasound axis image. by Eun-Seon Yang (19751340)

“…SBP showed an increasing trend, but this was not statistically significant (<i>p</i> = 0.108). Interestingly, we observed significant decreases in arterial stiffness and PWV in POST_VM when comparing with PRE_VM (<i>p</i><0.001 and <i>p</i><0.001, respectively). …”

Characteristics of study subjects. by Jung Eun Choi (563339)

“…There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations.…”

Patient enrollment and inclusion information. by Ruitian Song (11045127)

“…Patients who had undergone a shunt procedure exhibited a significantly reduced PVS compared to those who had not undergone the procedure. …”

Study variables. by Amit Timilsina (15203538)

“…Change in forest cover between 2011 and 2016 was significantly associated with a reduced probability of diarrhoea by 3.39% (Δy/Δx: −0.0339, 95% CI: −0.0141, −0.0535; p-value: 0.001), after adjusting for all other variables. …”

Descriptive statistics. by Amit Timilsina (15203538)

“…Change in forest cover between 2011 and 2016 was significantly associated with a reduced probability of diarrhoea by 3.39% (Δy/Δx: −0.0339, 95% CI: −0.0141, −0.0535; p-value: 0.001), after adjusting for all other variables. …”

Each types of tuberculosis ASMR in 1990 and 2021. by Xue Li (285380)

“…</p><p>Conclusion</p><p>Although the burden of TB in children and adolescents has decreased globally, the disease remains a major public health concern, especially in countries with low SDI. …”

Each types of tuberculosis ASDR in 1990 and 2021. by Xue Li (285380)

“…</p><p>Conclusion</p><p>Although the burden of TB in children and adolescents has decreased globally, the disease remains a major public health concern, especially in countries with low SDI. …”

Each types of tuberculosis ASIR in 1990 and 2021. by Xue Li (285380)

“…</p><p>Conclusion</p><p>Although the burden of TB in children and adolescents has decreased globally, the disease remains a major public health concern, especially in countries with low SDI. …”

Data for Fig 1. by Rachael M. Giersch (22331947)

“…We also observe a significant decrease in survival in animals that progress to >10% cancer in their hemolymph, while we see no effect on survival in clams with BTN that are long-term non-progressors. …”

Negative (Prednisone) and basal (ATP) control compounds binding to ALK protein. by Richard Junior Zapata Dongo (17912565)

S1 Data - by Richard Junior Zapata Dongo (17912565)

“…This interaction was further supported by a significant decrease of ALK phosphorylation in single and combination treatment with 300nM ABT-199. …”

Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. by Richard Junior Zapata Dongo (17912565)

RNA targets of Mod identified by RiP-Seq. by Amalia S. Parra (4173004)

“…Mod is expressed in larval brains and its loss leads to a significant decrease in the number of central brain NBs. …”

Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. by Richard Junior Zapata Dongo (17912565)

The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. by Richard Junior Zapata Dongo (17912565)