Presentation_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.pdf by Bin Zhang (64682)

“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”

Supplementary file 1_Multimodal MRI study of gray matter and functional connectivity abnormalities in adolescents with bipolar disorder.docx by Pengyu Zhu (1819939)

“…Background<p>Adolescent bipolar disorder (BD) is a severe psychiatric condition characterized by mood instability, with significant impacts on social and cognitive functioning. …”

Table 2_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Table 4_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Table 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Image 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.tif by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Table 3_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Table 6_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Table 5_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Table 7_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx by Weilin Cui (21758462)

“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”

Data Sheet 1_Antibacterial effects of coniferyl alcohol-derived dehydrogenation polymer on chlamydial infection in vitro.pdf by Anna Pfundner (22409281)

“…Infection and adhesion assays demonstrated a significant reduction in infection levels, suggesting that DHP/Alg directly targets Chlamydia elementary bodies, thereby disrupting their ability to adhere and initiate infection. …”

Data Sheet 1_Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation.zip by Raheem F. H. Al Aameri (14951800)

“…C57BL/6J mice treated with two cycles of cisplatin (3.5 mg/kg) showed a significant elevation in ABR thresholds, along with loss of outer hair cells and inner hair cells synapse. …”

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model by Merel Wauters (21333023)

“…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …”

Table 1_Exogenous myo-inositol enhances drought tolerance in maize seedlings by antioxidant defense, and photosynthetic efficiency.docx by Yuqi Liu (501183)

“…</p>Methods<p>In this study, we aimed to investigate the role of exogenous myo-inositol (MI) in alleviating drought stress in maize seedlings. …”

Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel by Yuzhen Lu (4402591)

“…<p><i>Metarhizium robertsii</i>, a fungal pathogen employed in pest biocontrol, can alkalize the surrounding environment, although the biological implications remain unclear. …”

Data Sheet 1_CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer.zip by Wenjing Wang (181404)

“…However, some patients still exhibit poor therapeutic outcomes. Platelets, as a critical component of blood, play a significant role in liver cancer progression by influencing angiogenesis and the tumor immune microenvironment.…”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…The regulatory mechanism of MrgC on UPR^mt was further explored in N2a and 293T cells.</p>Results<p>Mice with bone cancer pain showed improved mRNA and protein levels of UPR^mt-related molecules, increased MMP and ATP, decreased mitochondrial ROS levels in the spinal cord after receiving an intrathecal injection of BAM8-22. …”

Data Sheet 1_Comparative evaluation of artificial saliva and complete artificial saliva as solvent vehicles for in vitro toxicity testing of oral tobacco products.docx by Xuefei Cao (1700068)

“…</p>Results<p>The results showed comparable nicotine extraction efficiency between AS and CAS, with no significant impact from pouch cutting size or extraction duration. …”

LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p by Rouli Dai (17063211)

“…<p>Cerebral ischemia-reperfusion (CI/R) injury is a significant hurdle in ischemic stroke treatment. …”

Image_2_Study of epirubicin sustained–release chemoablation in tumor suppression and tumor microenvironment remodeling.jpeg by Liangliang Meng (9500122)

“…</p>Methods<p>In this study, we supposed to use polyethylene glycol (PEG) hydrogel as a drug carrier to improve the retention time of the drug to extend the exposure of tumor cells and investigate the feasibility of combination local Epirubicin injection with anti-PD-L1. …”