Showing 5,201 - 5,220 results of 5,845 for search '(( significantly ((we decrease) OR (a decrease)) ) OR ( significant decrease decrease ))~', query time: 0.59s Refine Results
  1. 5201

    <i>DANCR</i> regulated genes in SK-MEL-28 cells. by Stephanie M. E. Jones (12883691)

    Published 2025
    “…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …”
  2. 5202

    Supplementary Figures for AJP-Integr Reg Comp Physiol R-00035-2025R1 by Joshua Huot (20868279)

    Published 2025
    “…</b> <i>In vitro</i>, the C2C12 cultures exposed to GL261 exhibited myotube atrophy, consistent with a disrupted anabolic/catabolic balance. <i>In vivo</i>, carcass, heart, and fat mass were significantly reduced in the tumor-bearing mice. …”
  3. 5203

    Data Sheet 1_Global, regional, and national burden of fracture of vertebral column, 1990–2021: analysis of data from the global burden of disease study 2021.docx by Yanni Lan (9092615)

    Published 2025
    “…Background<p>Fractures of the vertebral column, encompassing various spinal injuries, represent a significant public health burden worldwide. These injuries can lead to long-term disability, reduced quality of life, and substantial healthcare costs.…”
  4. 5204

    Supplementary file 1_Tapered fiber probe-based optical cardiac pacemaker.docx by Yanzheng Xie (22596953)

    Published 2025
    “…</p>Methods<p>By leveraging the unique long-range focusing capability, we establish a tapered-fiber-probe (TFP) strategy enabling non-contact and highprecision near-infrared (NIR) optical pacing in zebrafish embryos, where sustained micron-scale spatial precision (3 μm FWHM) was achieved at physiologically relevant working distances.…”
  5. 5205

    <i>trus</i> mutant displays higher embryonic lethality. by Saeko Takada (21616085)

    Published 2025
    “…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”
  6. 5206

    Data - developmental timing. by Saeko Takada (21616085)

    Published 2025
    “…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”
  7. 5207

    <b>Species richness, composition and dominance of core and climate relicts of African Miombo woodlands</b> by Justice Muvengwi (22631075)

    Published 2025
    “…Species composition difference between sites were evaluated using analysis of similarity (ANOSIM). Our results revealed a pattern where species richness, the Shannon Wiener index, and evenness increased with decreasing relict size. …”
  8. 5208

    Data - <i>trus</i>RNAi wing size measurement. by Saeko Takada (21616085)

    Published 2025
    “…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”
  9. 5209

    Data Sheet 1_Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma.pdf by Jiatao Li (10033795)

    Published 2025
    “…Background<p>Asthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. …”
  10. 5210

    Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

    Published 2025
    “…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”
  11. 5211

    Data Sheet 2_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xlsx by Wenyong Liao (21669332)

    Published 2025
    “…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”
  12. 5212

    Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls by Wenyong Liao (21669332)

    Published 2025
    “…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”
  13. 5213

    Presentation 1_Deficits in medial prefrontal cortex parvalbumin expression and distraction-dependent memory in rats and mice in the sub-chronic phencyclidine model for schizophreni... by Katie R. Landreth (22518581)

    Published 2025
    “…TCSI testing showed that scPCP mice expressed diminished sociability overall and increased susceptibility to distraction for social memory, particularly for rearing behavior. There was a significant reduction in PVI density in the scPCP mouse mPFC.…”
  14. 5214

    Loss of b-cell K<sub>ATP</sub> reduces Ca<sup>2+</sup> sensitivity of insulin secretion and <i>Trpm5</i> expression by Nathaniel W. York (20410828)

    Published 2024
    “…Paradoxically, despite the initial insulin hypersecretion, many CHI cases, as well as K<sub>ATP</sub> knockout (KO) animals, eventually ‘crossover’ to undersecretion and even diabetes. Here we confirm that S<i>ur1</i> KO islets exhibit higher intracellular [Ca<sup>2+</sup>] (<a href="" target="_blank">[Ca<sup>2+</sup>]<sub>i</sub></a>) at all [glucose], but show decreased glucose-stimulated insulin secretion. …”
  15. 5215

    Data Sheet 1_Spatial and temporal variability in blue carbon accumulation in the largest salt marsh in British Columbia, Canada.docx by Karen E. Kohfeld (11936879)

    Published 2025
    “…Boundary Bay (BB) marsh is a 222-ha salt marsh in southern British Columbia, Canada, where construction began in 2023 to enhance the marsh as a natural defense against coastal flooding. …”
  16. 5216

    Table 1_Association between combined urinary phthalate metabolites exposure and grip strength among residents in Guangzhou, China.docx by Jinbin Chen (4468570)

    Published 2025
    “…BKMR model analysis revealed a significant negative correlation between co-exposure to urinary mPAEs and grip strength, with mMP being the most significant contributor.…”
  17. 5217

    Data Sheet 1_Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders.docx by Juanjuan Fang (413481)

    Published 2025
    “…After full adjustment for covariates, mLE8 exhibited a significant mediating role in the associations of both DI-GM (14.46% mediated effect, p < 0.001) and DI-GM beneficial (12.99% mediated effect, p < 0.001) with sleep disorders. …”
  18. 5218

    Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc by Wenping Sun (1465360)

    Published 2025
    “…</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…”
  19. 5219

    The inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication by Miaomiao Li (483829)

    Published 2025
    “…Western blot analysis showed that TMP269 treatment significantly suppressed PPRV replication in Vero and caprine endometrial epithelial cells (EECs). …”
  20. 5220

    Data_Sheet_1_Optimisation of Lactobacillus fermentation conditions and its application in the fermentation of salt-free sauerkraut.PDF by Wenlun Wang (18863641)

    Published 2024
    “…<p>To identify what are the dominant lactic acid bacteria (LAB) involved in the fermentation of salt-free sauerkraut, and optimize its industrial culture conditions, we isolated and identified a strain of LAB, which is referred to as Lactobacillus sp. …”