Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…We recently reported a vesicle trafficking protein Bet1L (Bet1 Golgi Vesicular Membrane Trafficking Protein Like) as a new molecule possibly linked to NMJ degeneration in ALS. …”

Growth of bacteria in various media and temperatures with or without Sf14 infection. by Nykki D. Ross (20933968)

School learning model dispositions data. by David A. Katz (10056006)

“…P-values<0.050 were considered significant. From 2019 to 2021, reported persistent feelings of sadness/hopelessness (2019 = 36.3%, 2021 = 41.3%), seriously considering suicide (17.0-18.7%), making suicide plan(s) (14.2-16.9%), and experiencing sexual dating violence in past 12 months (6.7-7.8%) increased significantly, while alcohol use (22.5-17.1%), binge drinking (8.5-6.2%), and marijuana use (20.2-14.3%) in past 30 days, ever prescription opioid misuse (16.0-13.2%), and gun-carrying (5.5-4.5%), physical fighting (22.3-17.3%), and any sexual violence (11.3-10.4%) in past 12 months decreased significantly. …”

Expression of the major capsid protein <i>gp34</i> gene in nutrient-poor (M9) or -rich (LB) conditions at various temperatures. by Nykki D. Ross (20933968)

Insulin-free survival in patients with and without FHD. by Clemens Plattner (21567706)

Proteomic and Transcriptomic Profiling Revealed Vital Molecular Events in the Transition from Goat Colostrum to Mature Milk by Xiao Zhang (152326)

“…Our results indicate that the milk protein changes were associated with a network of mammary gene expression changes; importantly, the prime factors include enhanced mammary growth/development, decreased protein translation, attenuated protein folding, and lower lip/carbohydrate metabolism. …”

Heterogeneity analysis. by Ying Zhao (16546)

“…Instrumental variables (IVs) were identified as genome-wide significant single-nucleotide polymorphisms (SNPs) with a significance threshold of <i>P </i>< 1 × 10⁻⁸ and an independence criterion of <i>r</i>² < 0.001. …”

Reverse MR analysis data. by Ying Zhao (16546)

“…Instrumental variables (IVs) were identified as genome-wide significant single-nucleotide polymorphisms (SNPs) with a significance threshold of <i>P </i>< 1 × 10⁻⁸ and an independence criterion of <i>r</i>² < 0.001. …”

SNP dressing by screening. by Ying Zhao (16546)

“…Instrumental variables (IVs) were identified as genome-wide significant single-nucleotide polymorphisms (SNPs) with a significance threshold of <i>P </i>< 1 × 10⁻⁸ and an independence criterion of <i>r</i>² < 0.001. …”

Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues. by Erienne G. Norton (9612079)

“…Two-tailed Student <i>t</i> test (<b>A</b>–<b>D</b>, <b>F</b>–<b>I</b>) or Benjamini–Hochberg test (<b>E</b>); NS, not significant. …”

Vps34 orchestrates transcriptional and epigenetic remodeling events corresponding to terminal eTreg differentiation during perinatal life. by Erienne G. Norton (9612079)

“…AP-1-related transcription factors with predicted decreased activity are labeled. See also <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.s016" target="_blank">S8 Table</a>. …”

Sensitivity analysis. by Ying Zhao (16546)

Biochemical data. by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Scoring of Disease Activity Index (DAI). by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Primers sequences used in this study. by Abdallah Tageldein Mansour (21158819)

“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) <i>IL-17</i>, <i>TNF-α</i>, and <i>IL-1β</i> (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”

Analysis of the correlation between pharyngeal microbiomics, metabolomics and clinical indicators between OC and HC. by Feng Gao (3548)

Bone-related serum chemistry endpoints: Aquamin (180-day treatment group) versus placebo. by Muhammad N. Aslam (6598001)

“…[Note: For the composite graph, inverse BALP values are plotted because while increased osteocalcin and TRAP5b are associated with improved bone metabolism, decreased BALP is reflective of improved bone metabolism].…”

The Beta diversity of soil bacterial community under different water and fertilizer application patterns (A, I1; B, I2; C, I3). by Xiaona Lyu (20871872)

Localization and expression of cell-to-cell connection proteins in bma-miRNA transfected and NC hLECs. by Hailey Johnson (18217167)

“…<p><b>(A)</b> FN1 (green) observed as a net-like structure in NC cells with nuclei shown in blue (DAPI). …”

Image2_Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.TIF by Tetyana P. Buzhdygan (19822401)

“…We found that ADMA disrupted physical barrier function as evident by significant decrease in electrical resistance and increase in paracellular permeability of hBMVEC monolayers. …”