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significantly mean » significantly less (Expand Search), significantly mediate (Expand Search), significantly impact (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
significantly mean » significantly less (Expand Search), significantly mediate (Expand Search), significantly impact (Expand Search)
we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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41
Baseline Characteristics of Included Patients.
Published 2025“…The risk of cardiovascular death was significantly decreased (HR 0.64, 95% CI 0.41–0.998, <i>P</i> = 0.049) and the risk of fracture non-significantly increased (HR 1.47, 95% CI 0.95–2.27, <i>P</i> = 0.08) in the intervention group compared to the control group.…”
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Characteristics of the included studies.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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44
Summary of results.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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45
Bias risk assessments for each RCT study.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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46
The flow chart of studies selecting.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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47
Funnel plots for intraoperative blood loss.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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48
Bias risk assessments for each RCS study.
Published 2025“…The combined findings showed that high-dose TXA was associated with a significant reduction in intraoperative blood loss [weighted mean difference (WMD) = -215.48, 95% confidence interval (CI) (-367.58, -63.37), P < 0.001], as well as a decreased likelihood of transfusion [risk ratio (RR) = 0.40, 95% CI (0.30, 0.53), P < 0.001]. …”
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49
Characteristics of JIA patients.
Published 2025“…Twelve studies published between 2003 and 2018 were analyzed, encompassing 1513 patients with a mean age of 11.4 years. Tumor necrosis factor alpha inhibitors were the predominant biologic agents used (75.8%), with a mean follow-up duration of 2 years post-biologic therapy initiation. …”
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50
List of excluded articles.
Published 2025“…Twelve studies published between 2003 and 2018 were analyzed, encompassing 1513 patients with a mean age of 11.4 years. Tumor necrosis factor alpha inhibitors were the predominant biologic agents used (75.8%), with a mean follow-up duration of 2 years post-biologic therapy initiation. …”
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<i>Oenocarpus bacaba</i> palm tree (A) and fruit (B).
Published 2024“…Serological cure was achieved in 34.6% of cases, and IgG titers decreased in 15.3%.</p><p>Conclusions and significance</p><p>We encountered several barriers in managing ACD, including population vulnerability, reliance on outdated diagnostic techniques, lack of standardized molecular biology methods, and limited therapeutic options. …”
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Clinical characteristics.
Published 2025“…Survival curves were estimated using the Kaplan-Meier plot and compared using the Log-rank test.</p><p>Results</p><p>Mean age at T2D diagnosis was significantly lower in the FHD group, while time to insulin initiation was independent from FHD status. …”
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54
Demographics of the enrolled patients.
Published 2025“…</p><p>Results</p><p>Eighty-eight patients were included (51 men and 37 women, mean age: 67.3 ± 13.4 years). The success rate in the seated position without the eye drop aid was 71.6%, and this rate decreased with increasing age; with the eye drop aid, the success rate improved significantly to 97.8%. …”
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Overhead view of the eye drop aid.
Published 2025“…</p><p>Results</p><p>Eighty-eight patients were included (51 men and 37 women, mean age: 67.3 ± 13.4 years). The success rate in the seated position without the eye drop aid was 71.6%, and this rate decreased with increasing age; with the eye drop aid, the success rate improved significantly to 97.8%. …”
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Summary statistics of key variables.
Published 2024“…We find that in developing countries, as urban economic density increases, innovation first increases and then begins to decrease beyond a certain point, with the decline being most prominent in the largest cities. …”
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Characteristics of the included studies.
Published 2025“…The pooling of dichotomous outcome data was achieved using relative risk (RR), with results presented within a 95% confidence interval (CI). We utilized the standard mean difference (SMD) and 95% CI for continuous outcomes. …”
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Extracted data and used for analysis.
Published 2025“…The pooling of dichotomous outcome data was achieved using relative risk (RR), with results presented within a 95% confidence interval (CI). We utilized the standard mean difference (SMD) and 95% CI for continuous outcomes. …”
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Excluded studies with reasons for exclusion.
Published 2025“…The pooling of dichotomous outcome data was achieved using relative risk (RR), with results presented within a 95% confidence interval (CI). We utilized the standard mean difference (SMD) and 95% CI for continuous outcomes. …”
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Overall analysis of randomized controlled trials.
Published 2025“…Stratification by a longer treatment duration of more than four months revealed that atorvastatin achieved the most significant reduction in IL-6 and TNF-α. …”