Showing 181 - 200 results of 738 for search '(( significantly ((we decrease) OR (a decrease)) ) OR ( significantly mediate decrease ))~', query time: 0.54s Refine Results
  1. 181

    Table 1_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.docx by Xiao Li (107004)

    Published 2024
    “…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”
  2. 182

    Image 3_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

    Published 2024
    “…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”
  3. 183
  4. 184

    Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

    Published 2025
    “…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
  5. 185

    Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

    Published 2025
    “…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
  6. 186

    Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

    Published 2025
    “…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
  7. 187

    Data Sheet 3_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

    Published 2025
    “…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
  8. 188

    Data Sheet 2_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

    Published 2025
    “…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
  9. 189
  10. 190
  11. 191

    Image1_AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics.TIF by Jingxia Du (8752482)

    Published 2024
    “…We found that Mdivi-1 significantly improved MMP, inhibited ROS production, reduced the expression of TNF-a, IL-6, IL-1β, Fis1, and Mff, and improved the expression of Mfn1 and Mfn2. …”
  12. 192
  13. 193

    Table 6_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  14. 194

    Table 1_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  15. 195

    Table 4_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  16. 196

    Table 3_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  17. 197

    Table 2_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  18. 198

    Table 7_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  19. 199

    Table 5_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... by Minseo Kim (773205)

    Published 2025
    “…In a previous study, we found that the microbiome composition of the carapace in lobsters with ESD differed from that of healthy individuals, with ESD-associated bacteria enriched in the green gland and testis. …”
  20. 200

    Table 1_Inverse associations of the lifestyle critical 9 with cardiorenal syndrome: the mediating role of the dietary inflammatory index.docx by Hongman Li (19546419)

    Published 2025
    “…DII shows a significant positive connection with CRS (p < 0.001), but DII indicates a decreasing trend when LC9 rises (β = −0.65, p < 0.001). …”