Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice by Julie Decock (44558)

“…Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”

Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models by Mezher, Nawal

“…ACSS2 inhibition significantly reduced the expression of pro-inflammatory cytokines such as Interleukin 8 (IL-8), IL-1β, and TNF-α, and attenuated activation of NF-κB and MAPK signaling pathways, as evidenced by decreased phosphorylation of p65 and ERK/MEK. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Total and segmental liver volume variations by Abdalla, Eddie

“…This reproducible, noninvasive procedure is necessary because significant interpatient variation is believed to exist in the relative contributions of the hepatic segments to TLV.11 CT volumetry accurately predicts TLV on the basis of body surface area or body weight,12 which may achieve the true goal of preoperative CT volumetry of the liver, that is to estimate the individual patient's hepatic metabolic demands after resection or transplantation.7 Complications associated with technical aspects of liver surgery are decreasing, and focus has concurrently shifted to analysis of postoperative complications after major hepatic resection and liver transplantation on the basis of liver remnant volume and graft volume.3., 4., 6., 7., 8. and 13. …”
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The effects of Organisational Ambidexterity and New Public Management on Public Sector Service Quality through Service Innovation by ALKAABI, SEEMA SAADY

“…Moreover, the bureaucratic structure of the public sector hinders any initiative to improve, meet the demand for better products and services and operate without necessarily increasing its expenditures and disbursements. Hence, the need to reduce bureaucracy may give rise to the increasing demand for service innovation to attain service quality and enhance performance. …”
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The effect of IL-1RA and IL-13 on cutaneous leishmaniasis in BALB/C mice as to hyperalgesia and the levels of IL-1b and IL-6. (c2005) by Hamdan, Hamdan Ghazi

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Local arterial vasoconstriction induced by octreotide in patients with cirrhosis by Chatila, Rajaa

“…FBF in the control arm was unchanged despite a significant decrease in systemic glucagon levels. Methacholine infusion increased FBF around 300%, which was not altered by the concomitant infusion of octreotide. …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009) by Daher, Jalil Y.

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Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages by Huseyin Enes Salman (18131794)

“…<p dir="ltr">Flow-driven hemodynamic forces on the cardiac tissues have critical importance, and have a significant role in the proper development of the heart. …”

A novel hybrid methodology for fault diagnosis of wind energy conversion systems by Khaled Dhibi (16891524)

“…Then, the sensitive and significant characteristics are transmitted to the RF model for classification purposes. …”

Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development by Al Saneh, Mounir

“…Our results showed that there is no difference in viability of the VWS patient cells compared to healthy control cells. However, a significant decrease in the migratory and adhesion ability of the VWS patient cells was detected compared to the control, which could account for the phenotype. …”
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What Drives the Crowd? Exploring Decision-Making Styles and Motivational Drivers in Entrepreneurship Crowdfunding by Daher, Tommy

“…Crowdfunding is increasingly being considered an innovative platform providing financial solutions for entrepreneurs, businesses, and not-for profit organizations that are facing difficulties in their ventures. …”
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Toward a Clearer Understanding of Value‐Based Healthcare: A Concept Analysis by Vahe Kehyayan (21241649)

“…Despite a growing interest in VBHC, a significant knowledge gap persists within the existing literature in the absence of a clear conceptualization of VBHC itself.…”

Experimental investigations on the performance of a thermo-mechanical refrigeration system utilizing ultra-low temperature waste heat sources by Ahmad K., Sleiti

“…Thus, this study fills a significant gap in the literature by (i) experimentally evaluating the performance of a new full-scale thermo-mechanical refrigeration (TMR) system at ultra-low temperatures ranging from 50 °C to 85 °C, (ii) characterizing its operation with different commercial refrigerants, and (iii) identifying optimal operating conditions and working fluids for the investigated TMR system. …”
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Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis by Evdokia Varamenti (8154642)

“…</p><h3>Conclusions</h3><p dir="ltr">The results showed significant alterations in oxidative stress and cytokine levels after acute exercise, ranging from moderate to extremely large. …”

Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis by Mohammed Maan Al-Salihi (13105835)

“…</p><p><br></p><h3>Results</h3><p dir="ltr">Data from 11 prospective clinical trials were included in this network meta-analysis. We found that dBHC significantly decreased recurrence and reoperation rates compared with TDC (RR = 0.55, CI, 0.33–0.90 and RR = 0.48, CI, 0.24–0.94, respectively). …”

Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome by Fayaz Ahmad Mir (11828354)

“…We measured 1069 serum metabolites and correlated them to clinical features. …”

Essays on the effect of excess compensation and governance changes on firm value by Dah, Mustafa A.

“…We document a noticeable reduction in CEO turnover in the post-SOX period. …”
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Policy Brief on Entrepreneurship in Lebanon Unlocking Potentials: Addressing Barriers and Empowering Entrepreneurs in Lebanon by Haj Youssef, Moustafa

“…Only 22% of men and 16% of women are aware of essential resources like financial aid, mentorship programs, and educational workshops. This gap underscores the necessity for targeted outreach, particularly for women, to promote gender equity in entrepreneurship. …”
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Experimental investigations on the performance of a thermo-mechanical refrigeration system utilizing ultra-low temperature waste heat sources by Ahmad K. Sleiti (14778229)

“…Thus, this study fills a significant gap in the literature by (i) experimentally evaluating the performance of a new full-scale thermo-mechanical refrigeration (TMR) system at ultra-low temperatures ranging from 50 °C to 85 °C, (ii) characterizing its operation with different commercial refrigerants, and (iii) identifying optimal operating conditions and working fluids for the investigated TMR system. …”