Alignment of the Taxane binding pocket sequences. by Jacopo Zattoni (21702634)

“…The results were analyzed using a consensus method to increase their reliability. We found that the amoeba’s mitotic tubulins show a significant number of changes that are expected to decrease their affinity for tubulin-targeting compounds. …”

Rank of mutation fitness. by Zhong-yi Lei (22552944)

“…Retrospective validation demonstrated that CoVPF achieved 20.7% higher accuracy compared to previous study. Furthermore, we found that accounting for epistasis was critical, as ignoring epistasis led to a 43% decrease in forecasting accuracy. …”

Key modeling details for CoVPF and controls. by Zhong-yi Lei (22552944)

“…Retrospective validation demonstrated that CoVPF achieved 20.7% higher accuracy compared to previous study. Furthermore, we found that accounting for epistasis was critical, as ignoring epistasis led to a 43% decrease in forecasting accuracy. …”

Morphological Change of Hydrate Caused by Ostwald Ripening and Sintering by Zelin Xu (14002343)

“…Hydrate Ostwald ripening and sintering were observable several weeks after the onset of formation, leading to a decrease in the particle number. Simultaneously, the particle size increased significantly without alteration of the overall hydrate saturation. …”

Morphological Change of Hydrate Caused by Ostwald Ripening and Sintering by Zelin Xu (14002343)

“…Hydrate Ostwald ripening and sintering were observable several weeks after the onset of formation, leading to a decrease in the particle number. Simultaneously, the particle size increased significantly without alteration of the overall hydrate saturation. …”

Tryptamine Metabolism and Functionalization in Gut Commensal Bacteria Expand Human Tryptamine Signaling Responses by Hyun Bong Park (1576939)

“…Despite their potential significance, the variety of functional small molecules known in the gut is relatively limited. …”

Dataset. by Megan Null (4621039)

“…We aimed to determine (1) the association between 6-hour UVA score and in-hospital mortality, and (2) if a decrease in UVA score from admission to 6 hours was associated with improved in-hospital mortality. …”

Supporting datasets for all figures. by Matthew Drill (22258391)

“…Inhibition of P2X7R with small molecule antagonist AZ10606120, for 72 hours significantly decreased U251 cell number (p < 0.0001), and significantly increased tumour cell death, as evidenced by increased LDH release (p < 0.001). …”

Antibodies used in immunofluorescence staining. by Hiroharu Maegawa (8087543)

“…To better establish their relationship in trigeminal neuropathic pain, we examined male rats with infraorbital nerve (ION) ligation. …”

CONSORT diagram. by Aina Gabarrell-Pascuet (17696594)

“…</p><p>Results</p><p>The study sample (N = 27) was mainly composed of females (74%) and the mean age was 74.26 years. 21 participants completed the intervention (22% drop-out rate). Statistically significant (<i>p</i><0.01) decreases in emotional loneliness and depressive symptoms were observed following the intervention. …”

Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions by Amie M. Solosky (20320255)

“…Therefore, rapid diagnosis of DAT is essential but also challenging. In this work, we performed multiomics analyses, specifically proteomic and lipidomic, on blood samples from 31 California sea lions. …”

Proteomic and Lipidomic Plasma Evaluations Reveal Biomarkers for Domoic Acid Toxicosis in California Sea Lions by Amie M. Solosky (20320255)

“…Therefore, rapid diagnosis of DAT is essential but also challenging. In this work, we performed multiomics analyses, specifically proteomic and lipidomic, on blood samples from 31 California sea lions. …”

Influence intensity of Pressure(a), AOD(b), Lai(c), ET(d), Dew(e) on nitrogen dioxide concentration. by Feifei Cheng (8985345)

S1 File - by Kathleen Kristensen (17525457)

“…Further research is needed to understand how the COVID-19 pandemic may have impacted PWIDs’ engagement with harm reduction services.…”

Chicago COVID-19 mitigation policy timeline. by Kathleen Kristensen (17525457)

“…Further research is needed to understand how the COVID-19 pandemic may have impacted PWIDs’ engagement with harm reduction services.…”

Partial behavioral switching. by Hiroyuki Ichijo (13891153)

Source data for Fig 2. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for lung metabolomics. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 5. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 1. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”