Data Sheet 1_CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis.docx by Ping Zhao (47228)

“…</p>Results<p>CD226 expression in the peripheral blood of pSS patients was significantly increased on T cells, CD19⁺ B cells and CD14⁺ monocytes, but significantly decreased on CD56⁺ NK cells.We identified a distinct CD226⁺CD19⁺ B cell subset that exhibited pathogenic features in pSS. …”

Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc by Yan Yu (56143)

“…Background<p>Breast cancer remains a leading cause of mortality among women worldwide, with existing therapeutic options often accompanied by significant side effects and a persistent risk of disease recurrence. …”

Image2_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF by J Bundy (19843944)

“…Here, using surface biotinylation and (N-(Ethoxycarbonylmethyl)-6-Methoxyquinolinium Bromide) MQAE-dye based fluorescence quenching, we show that upregulated GABA_AR are on the cell-surface in TNBC cell lines and mediate significantly higher chloride (Cl⁻) flux as compared to non-tumorigenic MCF10A cells. …”

Image1_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF by J Bundy (19843944)

“…Here, using surface biotinylation and (N-(Ethoxycarbonylmethyl)-6-Methoxyquinolinium Bromide) MQAE-dye based fluorescence quenching, we show that upregulated GABA_AR are on the cell-surface in TNBC cell lines and mediate significantly higher chloride (Cl⁻) flux as compared to non-tumorigenic MCF10A cells. …”

DataSheet1_Inhibiting glycosphingolipids alleviates cardiac hypertrophy by reducing reactive oxygen species and restoring autophagic homeostasis.pdf by Chunxin Jiang (5212205)

“…By Western blotting, we detected decreased intracellular expression of Sirt3 and elevated phosphorylation of JNK after phenylephrine stimulation, but this was reversed in cells pretreated with Genz-123346. …”

<b>Insight into the effects of citric acid on the transformation of chemical</b><b> speciation</b><b> of Cd in</b> <b>biochar amended contaminated soil:</b> <b>Implications for bio... by Renhui Miao (18618601)

“…The impacts of citric acid (a typical LMWOA) on the redistribution of Cd in contaminated soil amended by different amounts of biochar (1–5%) generated at various pyrolysis temperatures (300~700 °C) were investigated based on incubation experiments in this study. …”

Table 1_Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling.xlsx by Lanlan Sun (1798921)

“…</p>Results and discussion<p>The objective of this study was to investigate the impact of CSA on mitigating residual damage caused by Clo on maize and elucidate its mechanism. …”

Supplementary Material for: Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration by Rouse M. (20413172)

“…Paired t-tests identified 25 additional analytes that showed significant decreases (p<0.05) only without Bonferroni correction. …”

Presentation 1_Gender and age differences in the global burden of peptic ulcers: an analysis based on GBD data from 1990 to 2021.zip by Ruirui Tan (21188585)

“…In terms of future trends, the global incidence of PU is projected to continue decreasing over the next 15 years. The global prevalence is expected to improve, while PU-related mortality is likely to plateau without significant increases or decreases.…”

Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx by Jessica Alves Freitas (20974076)

“…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”

Table 1_Epicatechin gallate and its analogues interact with sortase A and β-lactamase to suppress Staphylococcus aureus virulence.docx by Fei Teng (201085)

“…The ability of β-lactam antibiotics to combat S. aureus infections is limited by the presence of β-lactamases in this pathogen. In this study, we determined that epicatechin gallate (ECG) and its analogues inhibited the transpeptidase activity of sortase A by interacting with it directly, and the biofilm formation and adhesion abilities of the bacterium decreased after treatment with ECG and its analogues. …”

Synthesis and biological evaluation of quinoxaline derivatives as ASK1 inhibitors by Xiaorui Han (1401655)

“…The Oil Red O staining experiment showed that <b>26e</b> decreased the lipid droplets in a dose-dependent manner. …”

Data Sheet 1_SWG5 regulates grain size and weight via sugar metabolism-mediated signaling in rice.pdf by Wenhui Lu (1999657)

“…<p>Grain size significantly affects rice yield and quality. Although several genes that regulate grain size have been identified, their mechanisms remain unclear. …”

Water Hyacinth as a Renewable Source of Cellulose Nanofibers: Fabrication and Properties of Optically Transparent Nanocomposites by Supachok Tanpichai (2084065)

“…Moreover, the CNF nanopaper significantly decreased the coefficient of thermal expansion of the acrylic resin from 192.3 to 16.3 ppm K⁻¹, which is comparable to that of borosilicate glass. …”

Table 1_WGCNA-ML-MR integration: uncovering immune-related genes in prostate cancer.docx by Jing Lv (128179)

“…In q-PCR experiments conducted on tumor tissues and adjacent non-cancerous tissues from prostate cancer patients, it was found that: compared to the adjacent non-cancerous tissues, the expression level of ARHGEF38 in prostate cancer tumor tissues significantly increased, while the expression levels of SLC14A1, NEFH, MSMB, KRT23, and KRT15 significantly decreased. …”

Table 6_Immunosuppression of spleen in mice treated with erythropoietin: transcriptomic and immunological analysis.xlsx by Xinyi Lyu (14756739)

“…When using this model, we found that EPO treated mice showed significant splenomegaly. …”

Table1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.xlsx by Yunxia Zhang (30848)

“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. …”

Table 4_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx by Weiwei Zheng (140828)

“…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …”

Table 2_Immunosuppression of spleen in mice treated with erythropoietin: transcriptomic and immunological analysis.xlsx by Xinyi Lyu (14756739)

“…When using this model, we found that EPO treated mice showed significant splenomegaly. …”

Data Sheet 1_Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and... by Zachary D. Wallen (19986522)

“…Known associations between genomic alterations and immunotherapy markers were observed including significantly lower TMB levels in tumors with therapy-associated alterations and significantly higher PD-L1 levels in tumors with ALK, MET, BRAF, or ROS1 driver mutations. …”