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significantly improves » significantly improved (Expand Search), significantly improve (Expand Search), significantly improving (Expand Search)
improves decrease » improves disease (Expand Search), improve disease (Expand Search), improved urease (Expand Search)
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5441
Table 2_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.xlsx
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5442
Image 2_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5443
Table 2_Magnesium application partially reversed the negative effects of mulching on rhizosphere nitrogen cycling in a Phyllostachys praecox forest.docx
Published 2025“…To address this, our study investigated rhizosphere nitrogen cycling in Lei-bamboo across a short-term degradation cycle. We found that mulching enhanced the abundance of 16S-rRNA and nitrogen-cycling functional genes. …”
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5444
Image 7_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5445
Hypermutability of <i>Mycolicibacterium smegmatis</i> due to ribonucleotide reductase-mediated oxidative homeostasis and imbalanced dNTP pools
Published 2025“…The Msm-Y252A displayed a 1.9-fold decrease in dATP and increases in dGTP (1.6-fold), dTTP (9.0-fold), and dCTP (1.3-fold). …”
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5446
Table 1_Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial.pdf
Published 2025“…MB was associated with a significant decrease in cytophilic subclasses IgG1 and IgG3 to S and S2, and IgA to RBD, S and S2 in CCP units IgA to RBD, S and S2 in CCP units, without a reduction in neutralization titer and with a modest increase in IgG2 to RBD and S.…”
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5447
Image 6_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5448
Image 1_Expansion of CD57+ CD8 T cells in common variable immunodeficiency with hepatopathy and CMV infection.pdf
Published 2025“…</p>Results<p>The expansion of CD57<sup>+</sup> CD8 T cells was part of the previously described immune alteration, including altered CD4/CD8 ratio and a decrease in naïve CD4 T cells. The loss of significant association with increasing age might corroborate the suggestion of premature immunosenescence in CVID. …”
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5449
Image1_ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity.JPEG
Published 2024“…</p>Methods<p>We performed a prospective study in 45 healthy athletes. …”
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5450
Table 1_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.xlsx
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5451
Image 4_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5452
Image 1_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5453
Table 1_Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study.xlsx
Published 2025“…Through targeted management, some antibiotics showed trends of increased or decreased usage. The detection rates of Methicillin-Resistant Staphylococcus aureus and Extended-spectrum β-lactamase-producing Escherichia coli did not show a significant decrease.…”
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5454
Image 8_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5455
Image 5_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5456
Data Sheet 2_Toxocariasis in children: seroprevalence after 15 years in a major city in Brazil.docx
Published 2025“…As no mitigatory actions were carried out between the surveys, we speculate that environmental contamination and child exposure to Toxocara spp. remained steady. …”
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5457
Table 1_Magnesium application partially reversed the negative effects of mulching on rhizosphere nitrogen cycling in a Phyllostachys praecox forest.xlsx
Published 2025“…To address this, our study investigated rhizosphere nitrogen cycling in Lei-bamboo across a short-term degradation cycle. We found that mulching enhanced the abundance of 16S-rRNA and nitrogen-cycling functional genes. …”
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5458
Data Sheet 1_Toxocariasis in children: seroprevalence after 15 years in a major city in Brazil.pdf
Published 2025“…As no mitigatory actions were carried out between the surveys, we speculate that environmental contamination and child exposure to Toxocara spp. remained steady. …”
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5459
Image 3_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif
Published 2025“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”
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5460
Table 1_Expansion of CD57+ CD8 T cells in common variable immunodeficiency with hepatopathy and CMV infection.pdf
Published 2025“…</p>Results<p>The expansion of CD57<sup>+</sup> CD8 T cells was part of the previously described immune alteration, including altered CD4/CD8 ratio and a decrease in naïve CD4 T cells. The loss of significant association with increasing age might corroborate the suggestion of premature immunosenescence in CVID. …”