Image 9_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…The unexplored potential of chemical checkpoint inhibitors in rejuvenating immune responses prompted our investigation.</p>Methods<p>We focused on CCT007093, a Wip1 inhibitor, screened for its distinctive capacity to simultaneously decrease PD-1 and FcγRIIB expression in B cells.…”

DataSheet1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.PDF by Zhen Kang (335450)

“…</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. Furthermore, the likelihood of developing PPD appears to decrease with increasing gestational age at the time of the first childbirth.…”

Table1_Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis.XLSX by Zhen Kang (335450)

“…</p>Conclusion<p>The study indicates that AFB is a significant risk factor for PPD. Furthermore, the likelihood of developing PPD appears to decrease with increasing gestational age at the time of the first childbirth.…”

Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf by Fisal Tantoush (20936264)

“…<p>Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor immunization responses afflict patients. …”

3D modelling of the impact of stellar activity on tidally-locked terrestrial exoplanets: atmospheric composition and habitability (dataset) by R Ridgway (9137141)

“…We find that coronal mass ejections abiotically generate significant levels of potential bio-signatures such as N2O. …”

Datasheet1_Hyperbaric effects on heart rate in professional SCUBA divers in thermal water.pdf by Luigi Fattorini (19758798)

“…</p>Results<p>In STD phase, HR slope obtained by regression decreased with depth. A significant difference was found between the slope during STD at −20 vs. −40 m (p ≤ 0.05).…”

Data Sheet 1_Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure.docx by Bochao Ma (14572143)

“…Similarly, the Young's modulus of RGC axons decreased by 45.6%, 70.9%, and 75.9% over the same time points. …”

Table 1_Exploring the effect of plant nitrogen concentration on the nitrogen nutrition index of winter wheat under controlled irrigation conditions.pdf by Mingxia Wang (804462)

“…Introduction<p>The nitrogen nutrition index (NNI) of winter wheat decreased under water deficit conditions, primarily due to an increase in the critical nitrogen concentration (%N_c) associated with a reduction in shoot biomass (SB). …”

A reduced expression level of PfATP2-HA does not affect the resting pH_cyt in <i>P. falciparum</i> parasites or pH_cyt dysregulation by MMV665794 or MMV007224. by Deyun Qiu (8871143)

“…(<b>F,I)</b> The rate of pH_cyt decrease was estimated from the initial linear portions of the traces for each concentration of MMV665794 (<b>F</b>; first 300-2400 s; n = 4) and MMV007224 (<b>I</b>; first 2400 s; n = 3). …”

Supplementary file 1_Influence of circadian rhythm on the determination of the IMMune age indeX (IMMAX).docx by Sina Trebing (22578458)

“…</p>Results<p>While individual immune cell ratios showed changes during the day, we determined no significant variability of the IMMAX score between the measurements. …”

Table 1_The impact of diagnosis-related group-based medical insurance payment model on the prognosis and nursing care of patients undergoing composite trabeculectomy: a retrospecti... by Yu Wang (12152)

“…As part of the nationwide reform of DRG medical insurance payment methods, hospitals are facing increased pressure to decrease average length of stay and improve efficiency within payment cap of different diseases. …”

Data Sheet 1_Huoxue-Jiangtang decoction ameliorates type 2 diabetes in high-fat diet and streptozotocin-induced rats.pdf by Maosheng Lee (13041531)

“…Moreover, the levels of glycogen synthetase (GS), hexokinase, superoxide dismutase (SOD), glycogen, and muscle glycogen in the HXJT group significantly increased relative to those in untreated T2DM group, while TNF-α levels decreased observably. …”

A Comparison Study of Open Source LLMs for HPC Tickets Answering by Zhao Zhang (17060598)

“…In collaboration with Princeton University and Rutgers University, hpcGPT uses generative artificial intelligence (AI) and integrates heterogeneous data sources with different update frequencies to enhance the user support service quality and efficiency, decrease the response time, and improve precision of the support. …”

Serum phosphorus level. by Naoki Suzuki (308620)

“…Lanthanum carbonate prescriptions decreased significantly in the tenapanor group and were largely replaced by low-dose tenapanor.…”

Characteristics of the study participants. by Naoki Suzuki (308620)

“…Lanthanum carbonate prescriptions decreased significantly in the tenapanor group and were largely replaced by low-dose tenapanor.…”

Serum albumin level. by Naoki Suzuki (308620)

“…Lanthanum carbonate prescriptions decreased significantly in the tenapanor group and were largely replaced by low-dose tenapanor.…”

Table1_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.xlsx by Yunxia Zhang (30848)

“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. …”

Data Sheet 1_CARTOON-based educational intervention for children to foster hygiene knowledge and emotional resilience in preschool children: a randomized controlled trial.pdf by Philipp Steinbauer (10792029)

“…While children's physical health may not be severely affected, their psychological well-being is a significant concern. Therefore, we developed an interdisciplinary psychoeducational intervention program for children named CARTOON. …”

DataSheet2_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.pdf by Yunxia Zhang (30848)

“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. …”

Data Sheet 1_Upright radiotherapy for breast cancer: a pre-clinical study considering photon and proton beam access, plus arm positioning.docx by Gordon Sands (22817087)

“…The use of the Chabner XRT Bra significantly reduced the size of the ISF, which may help lower skin toxicity, as well as the field length required for treatment, potentially decreasing unwanted lung dose.…”