بدائل البحث:
significantly small » significantly smaller (توسيع البحث), significantly impact (توسيع البحث), significantly impair (توسيع البحث)
marked decrease » marked increase (توسيع البحث)
small decrease » small increased (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
significantly small » significantly smaller (توسيع البحث), significantly impact (توسيع البحث), significantly impair (توسيع البحث)
marked decrease » marked increase (توسيع البحث)
small decrease » small increased (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), nn decrease (توسيع البحث)
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Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis
منشور في 2025"…We found that FHND5032 significantly upregulated miR-124 expression in macrophages, surpassing the clinical-stage comparator ABX464 in vitro and in vivo. …"
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
منشور في 2024"…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …"
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
منشور في 2024"…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …"
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
منشور في 2024"…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …"
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
منشور في 2024"…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …"
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Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer
منشور في 2024"…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …"
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S1 Data -
منشور في 2024"…The square root of the detectable connectivity r = 0.09 suggests that only 0.81% of the connectivity is explained by working memory-related time course fluctuations. Null hypothesis significance testing (NHST)-based analysis revealed that within-subject time course reliability markedly affects the significance levels at which paths can be detected at the group level. …"
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Connectivity statistics.
منشور في 2024"…The square root of the detectable connectivity r = 0.09 suggests that only 0.81% of the connectivity is explained by working memory-related time course fluctuations. Null hypothesis significance testing (NHST)-based analysis revealed that within-subject time course reliability markedly affects the significance levels at which paths can be detected at the group level. …"
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Data and code from: Limited responses of lizard assemblages to experimental fire regimes in an Australian tropical savanna
منشور في 2025"…We found no significant variation in total lizard abundance or the collective abundances of mesic, semi-arid or widespread biogeographic groups. …"
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Image 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf
منشور في 2025"…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…"