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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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14961
Alcohol perceptions and driving decisions among adolescents: Exploring the role of peer and parental influences in Virginia
Published 2025“…<p>This study aims to explore the role of peer and parental influences on adolescent driving behaviors, particularly concerning distracted and alcohol-impaired driving, in light of the significant number of road accidents and fatalities involving young drivers.…”
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14962
Data Sheet 1_Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells.pdf
Published 2025“…<p>Previously we have shown that H2-congenic recombinant mice of the B6.I-9.3 (H2-Ab1<sup>j</sup>) strain are significantly more susceptible to tuberculosis (TB) infection compared to their C57BL/6 (B6, H2-A<sup>b</sup>) ancestors. …”
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14963
DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx
Published 2024“…However, the global age-specific death rate significantly decreased from 2.96 (2.76, 3.15) to 2.86 (2.61, 3.11), and the age-specific DALY rate remained stable. …”
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14964
DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx
Published 2024“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”
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14965
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”
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14966
Table 4_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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14967
Table 2_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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14968
Table 3_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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14969
Table 1_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.docx
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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14970
Table 5_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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14971
Data Sheet 1_Synergistic amelioration of renal oxidative stress, inflammation, and fibrosis by combination of metformin and Clinacanthus nutans leave extracts in a type 2 diabetic...
Published 2025“…Additionally, DMCOM significantly decreased malondialdehyde levels. Notably, diabetic rats treated with DMCOM exhibited a significant reduction in parameters associated with renal dysfunction, as evidenced by decreased inflammation markers, along with downregulated fibrotic markers.…”
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14972
Table 6_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf
Published 2025“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”
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14973
ELISA kit information.
Published 2025“…<i>PTGFR</i> and <i>JNK</i> mRNA levels, MMP9 and ADH7 protein levels increased significantly in AN-LSCs after 0.313 μg/mL travoprost treatment (p≤0.039), while NF-κB and ADH7 protein levels decreased significantly in LSCs using 0.313 μg/mL travoprost (p=0.039; p<0.001).…”
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14974
Supplementary file 1_Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms.docx
Published 2025“…<p>Mechanical strain plays a significant role in lung pathophysiology. Current two-dimensional (2D) in vitro models fail to capture the lung's dynamic mechanical environment. …”
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14975
Image 3_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg
Published 2025“…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …”
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14976
Table 1_Global, regional, and national trends in the incidence of pneumoconiosis among populations aged 20 and above from 1990 to 2021.xlsx
Published 2025“…Utilizing data from the Global Burden of Disease (GBD) 2021, we have updated the epidemiological trends of pneumoconiosis.…”
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14977
Azole drugs have differential efficacy in varied models of immunosuppression in larval zebrafish hosts
Published 2025“…<p>Fungal infections are an increasing cause of mortality in immunosuppressed human patients, and antifungal drug treatments are still ineffective in a significant percentage of cases. A gap in our understanding of antifungal drug treatment is whether different drugs have differential efficacy in hosts that are experiencing different forms of immunosuppression.…”
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14978
Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx
Published 2025“…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”
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14979
Table 1_Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer.xlsx
Published 2025“…Notably, mitochondrial haplogroup D4 was significantly associated with a decreased risk of developing EC. …”
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14980
Image 2_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”