Data Sheet 1_The global, regional, and national impact of laryngeal cancer from 1990 to 2021, along with forecasts for 2050: a comprehensive analysis for the Global Burden of Disea... by Tingting Duan (5181482)

“…</p>Results<p>In 2021, LC increased with age and decreased after the age of 70. …”

Table 1_Efficacy of thymosin α1 for sepsis: a systematic review and meta-analysis of randomized controlled trials.docx by Bin Gu (223694)

“…These observations underscore the significance of personalized immunotherapy strategies in forthcoming clinical trials.…”

<b>Characterizing the role of PP2AB'' family subunits in mechanical stress response and plant development through calcium and ABA signaling in </b><b><i>Arabidopsis thaliana</i></b... by Hyuk Sung Yoon (19985262)

“…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb''αβγδ</i> mutant compared to wild type leaves. …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”

Image 2_Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules.tif by Qiuping Lin (3091146)

“…In the monocytes of CAL patients, MCH-II is a significantly increased signal and RESISTIN is a significantly decreased signal compared to non-CAL counterpart.…”

The analgesic effect of total saponins of Tribulus terrestris on neuropathic pain was studied based on TLR4/NF-κB pathway by Wu-Xia Guo (20832169)

“…The protein expression levels of NF-κB and TLR4 in the spinal dorsal horn of the injured side were significantly increased accompanied by elevated levels of inflammatory mediators IL-1β, IL-6, and TNF-ɑ. …”

DataSheet1_Effects of inulin-type oligosaccharides (JSO) from Cichorium intybus L. on behavioral deficits induced by chronic restraint stress in mice and associated molecular alter... by Caihong Yao (15344128)

“…Notably, JSO reduced feeding latency in the NSFT, increased time spent in the center in the OFT, enhanced time and entries into open arms in the EPMT, and decreased immobility time in the TST and FST (P< 0.01). …”

Image 3_Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules.tif by Qiuping Lin (3091146)

“…In the monocytes of CAL patients, MCH-II is a significantly increased signal and RESISTIN is a significantly decreased signal compared to non-CAL counterpart.…”

Data Sheet 3_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx by Xiaodong Wang (66801)

“…Compared to the control group, the mRNA expression of MMP9, HSP90AA1, SRC, EGFR, and ALB decreased (p< 0.01), while the apoptosis-related gene CASP3 increased in both the drug intervention (80 μmol/L β-sitosterol) and positive drug groups (80 μmol/L methotrexate).…”

Semaglutide ameliorates diabetes-associated cognitive dysfunction in mouse model of type 2 diabetes by Yan Zhu (112437)

“…Immunofluorescence showed increased LRP1 expression and decreased apoptosis. …”

Table 1_Effects of compound lactic acid bacteria on the quality and microbial diversity of alfalfa silage in saline-alkali soils.xlsx by Si-Yi Wang (209728)

“…The results of the microbial community showed that compared with the non-additives group, the Shannon index decreased and the Simpson index increased in the compound lactic acid bacteria group, indicating a significant reduction in microbial diversity in the silage environment (P < 0.05). …”

Data Sheet 1_Response of alfalfa growth and rhizosphere properties to soil phosphorus supply and mowing in a salt-affected soil.docx by Junjie Tian (5738408)

“…The yield of alfalfa increased with higher shoot P concentration. Furthermore, mowing significantly reduced rhizosphere carboxylates concentration (30.4%-100%) and APase activity (39.8%-75.0%) across all P treatments. …”

Supplementary file 1_Differential adaptations of japonica rice to submergence stress during the tillering stage under various seedling cultivation and transplanting methods.docx by Sumei Duan (18711099)

“…Over two-thirds of tillers survived under complete submergence for up to 7 days during the tillering stage. Submergence significantly affected POD and SOD activities, MDA and PRO contents, and SPAD values, characterized by initial increases followed by decreases in antioxidant enzyme activities, MDA accumulation, and PRO content elevation. …”

Data Sheet 2_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx by Xiaodong Wang (66801)

“…Compared to the control group, the mRNA expression of MMP9, HSP90AA1, SRC, EGFR, and ALB decreased (p< 0.01), while the apoptosis-related gene CASP3 increased in both the drug intervention (80 μmol/L β-sitosterol) and positive drug groups (80 μmol/L methotrexate).…”

Table 1_Supplementation of Yupingfeng polysaccharides in low fishmeal diets enhances intestinal health through influencing the intestinal barrier, immunity, and microflora in Macro... by Mingyang Liu (426690)

“…Microbial community analysis showed reduced diversity and altered composition in the LF group, with increased Proteobacteria and decreased Firmicutes, which were partially restored by YPF. …”

Table1_GLYCINE betaine and seaweed-based biostimulants improved leaf water status and enhanced photosynthetic activity in sweet cherry trees.docx by Sílvia Afonso (20456483)

“…Biostimulants, especially EM, demonstrated a significant positive effect (p ≤ 0.001) on total phenolic content, with increases of approximately 25% to 50% in treated leaves. …”

Image 2_CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model.tif by Xue Zhang (166886)

“…</p>Results<p>CD155 expression in hepatocytes was significantly increased—approximately 2-fold compared to Sham controls—and predominantly localized near lesion sites. …”

Data Sheet 1_Effects of compound lactic acid bacteria on the quality and microbial diversity of alfalfa silage in saline-alkali soils.zip by Si-Yi Wang (209728)

“…The results of the microbial community showed that compared with the non-additives group, the Shannon index decreased and the Simpson index increased in the compound lactic acid bacteria group, indicating a significant reduction in microbial diversity in the silage environment (P < 0.05). …”

Image 1_CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model.tif by Xue Zhang (166886)

“…</p>Results<p>CD155 expression in hepatocytes was significantly increased—approximately 2-fold compared to Sham controls—and predominantly localized near lesion sites. …”