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A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis
Published 2022“…Since several transcriptome studies have shown a significantly decreased expression of DCD in HS skin, we hypothesised that the identified frameshift insertion was a loss-of-function mutation that might be associated with HS susceptibility in this family. …”
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Unveiling into Genetic Architecture of Transgenerational Stress Memory via Promoting Drought Tolerance in Barley
Published 2024“…The decrease in G% was 19% and the decrease in GP was 67%. …”
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Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre...
Published 2022“…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …”
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Wind energy potential along the onshore and offshore Qatar
Published 2020“…Compared to the earlier studies, in this work, we have assessed the wind power at inland and o?…”
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Ocean Acidification and Carbonate System Geochemistry in the Arabian Gulf
Published 2020“…We calculated the nitrate corrected and salinity normalized tracer, Alk*. …”
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67
Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment
Published 2023“…The lack of disease-modifying therapies affects millions of patients globally, causing a massive economic burden due to these complications. Significantly, adipose tissue inflammation was implicated in the pathogenesis ofmetabolic syndrome, diabetes, and obesity. …”
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Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischemia.
Published 2017“…Our aim was to examine the neovascular potential under hypoxic conditions of ASCs-derived from thymic (thymASCs) and subcutaneous (subASCs) AT from 39 subjects with and without type 2 diabetes mellitus (T2DM) and of different ages who were undergoing coronary bypass surgery (CBS). We confirmed a significant decrease in the percentage of CD34+ CD31- CD45- subASCs in the cell yield of subASCs and in the survival of cultured endothelial cells in the medium conditioned by the hypox-subASCs with increasing patient age, which was not observed in thymASCs. …”
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
Published 2022“…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …”
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70
SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle
Published 2017“…Furthermore, increased levels of K63 and muscle RING finger 2 (MuRF2) protein could also be important enhancers of muscle mass. We report here that the levels of miR1 and miR133a decrease in hypertrophy and negatively correlate with muscle mass, SIRT1 and Nampt levels. …”
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71
Automatic Sleep Arousal Detection Using State Distance Analysis in Phase Space
Published 2018“…We first show how the states distance matrices of a complex system can be reconstructed to decrease the effect of false neighbors. …”
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Corporate governance and cost of debt financing: Empirical evidence from Canada
Published 2018“…In addition to the Board Composition and the Disclosure sub-indexes, we also find a significant negative relationship between shareholder rights sub-index and the cost of debt for issuers headquartered in Quebec. …”
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Nutritional quality and health risk of pepper fruit as affected by magnesium fertilization.
Published 2020“…As a result, Mg fertilization decreased the comprehensive nutrition level of pepper by 16.6%. …”
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Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…Stretching the RPV also significantly increased ROS generation after 1 hour, whereas APN significantly decreased mechanical stretch-induced ROS production. …”
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75
THE ASSOCIATION BETWEEN SOFT DRINK CONSUMPTION AND BONE MINERAL DENSITY AMONG QATARI WOMEN: ANALYSIS OF QATAR BIOBANK DATA
Published 2019“…Reports from these studies presented conflicting findings. Some suggesting significant decreases in BMD levels due to soft drink consumption, while others find null associations. …”
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OIL PRICE SHOCKS AND STOCK PRICE INFORMATIVENESS: EVIDENCE FROM GCC FIRMS
Published 2024“…We also show that supply (demand) shocks decrease (increase) stock price informativeness. …”
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Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar
Published 2018“…Highest number of patients with a comorbidity of Diabetes (12.85%), followed by Hypertension (10.54%). We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). …”
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Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals.
Published 2024“…The significant decrease in NT-proBNP observed in individuals with insulin resistance may be attributed to a direct or indirect enhancement in glutathione production, which is regarded as a compensatory mechanism against oxidative stress. …”
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
Published 2025“…Meta-regression showed a significant decrease in SSI incidence in HICs. Maternal factors, procedural aspects, and care quality were associated with SSI. …”
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Heme Oxygenase Isoform 1 Regresses Cardiomyocyte Hypertrophy Through Regressing Sodium Proton Exchanger Isoform 1 Activity
Published 2014“…Results: Our results showed a significant decrease in HO-1 mRNA expression in cardiomyocytes expressing active NHE1 (74.84 ± 9.19 % vs. 100 % normal NHE1 expression, p<0.05). …”
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