Data Sheet 1_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy... by Julie Stichova (19729855)

“…The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4⁺ T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”

Table 1_Improved quality of life in head and neck cancer patients treated with modern arc radiotherapy techniques – A prospective longitudinal analysis.docx by Eva Yu-Hsuan Chuang (19724116)

“…Global QOL, physical function, symptoms of sticky saliva, cough, feelings of illness and weight loss improved significantly between 2 weeks and 3 months. There was no significant difference between 3 and 6 months. …”

Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx by Susan Carroll (17468)

“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”

Data Sheet 1_Integration of hepatic lipidomics and transcriptomics reveals dysregulation of lipid metabolism in a golden hamster model of visceral leishmaniasis.zip by Dongmei Yuan (291583)

“…In the GPL metabolism and AA metabolism pathways, the transcription levels of genes such as phospholipase A2 (PLA2) family enzymes, cyclooxygenase-2 (Cox-2), arachidonate 5-lipoxygenase (Alox5), and hematopoietic prostaglandin D synthase (Hpgds), all of which regulate phospholipid hydrolysis and lipid mediator production, were significantly increased. Additionally, we found that the expression of lysophosphatidylcholine acyltransferase 1/2 (Lpcat1/2), the enzyme regulating PC remodeling, was upregulated and that the levels of saturated PCs (PC30:0, PC32:0, and PC34:0) were simultaneously significantly increased simultaneously. …”

Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx by Susan Carroll (17468)

“…On the contrary, a chaotic home environment is associated with decreased well-being. We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”

Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation by Runze Wang (21792959)

“…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …”

Data Sheet 1_The Sdp-SH3b2 domain contained in Lactobacillus johnsonii N6.2-derived extracellular vesicles inhibit murine norovirus replication.pdf by Danilo R. da Silva (8542623)

“…We found that RAW 264.7 Macrophages treated with EVs significantly decreased the levels of MNV-1 genome. …”

Image 1_PipC affects the virulence of Salmonella enterica serovar Enteritidis and its deletion strain provides effective immune protection in mice.tif by Lu Zhang (50563)

“…Meanwhile, the expression levels of SPI-1-related genes (invH, sipA, sipB, sipC, sopB, and sopE2) and SPI-2-related genes (spvB, ssrA, orf245, ssaS, ssaT, ssaU, sseB, and sseD) encoding the Salmonella type III secretion system (T3SS) were found to be decreased, leading to a significant reduction in the bacteria’s invasion and intracellular survival abilities. …”

Image 2_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 1_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 6_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 4_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 2_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 5_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 3_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Image 1_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 1_Effects of Veratrum nigrum expansion on soil microbial community structure in inner Mongolian mountain steppe.docx by Bo Pang (164741)

“…Compared with CK, the fungal Chao1 and Shannon diversity increased significantly in the S treatment, whereas the abundance of oligotrophs (Basidiomycota) decreased significantly. …”

Data Sheet 1_Efficacy of music intervention on pain and anxiety in patients undergoing cataract surgery: a systematic review and meta-analysis.docx by Lanzhu Su (21570704)

“…</p>Results<p>Eighteen studies with 2,262 participants were included. Music therapy significantly reduced anxiety levels, as demonstrated by a notable decrease in Visual Analog Scale (VAS) anxiety scores (SMD = -7.10, 95% CI: -12.25 to -1.95) and State-Trait Anxiety Inventory (STAI) scores (SMD = -1.26, 95% CI: -1.85 to -0.66). …”

Supplemental Figures by Danielle A. Jeffrey (21187329)

“…Significantly, we are the first to report a reduction in the muscle-specific isoforms of FXR1 in pediatric DCM patients, underscoring an age-specific regulation of FXR1 expression.…”

Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…In particular, the increase in bile acid-related metabolites in the 2 mg BID group was significantly greater than that in the placebo group, and unsaturated fatty acid-related metabolites decreased in both the 2 mg BID group and the placebo group, but there was no significant difference between the two groups. …”