Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
decrease ros » increased ros (Expand Search), decreased mor (Expand Search), decrease rice (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
decrease ros » increased ros (Expand Search), decreased mor (Expand Search), decrease rice (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals
Published 2019“…<div><p>Findings</p><p>Here, we demonstrate that OP2113 (5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione, CAS 532-11-6), synthesized and used as a drug since 1696, does not act as an unspecific antioxidant molecule (i.e., as a radical scavenger) but unexpectedly decreases mitochondrial reactive oxygen species (ROS/H<sub>2</sub>O<sub>2</sub>) production by acting as a specific inhibitor of ROS production at the I<sub>Q</sub> site of complex I of the mitochondrial respiratory chain. …”
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Overview of the WeARTolerance program.
Published 2024“…<div><p>The stigma surrounding mental health remains a significant barrier to help-seeking and well-being in youth populations. …”
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Y-27632 collaborated with BA to attenuate the increase in the integrity and decrease in the permeability of epithelial barrier injury induced by LPS in Caco2 monolayers.
Published 2024“…<p>(<b>A)</b> Y-27632 collaborated with BA to attenuate the effect of LPS on TEER in Caco2 cells on days 1–22. (<b>B)</b> Y-27632 collaborated with BA to attenuate the effect of LPS on TEER in Caco2 cells on day 22. …”
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ROS reduces the expression of Akt3, WDR12 and Aurora B leading to micronuclei.
Published 2025Subjects: -
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