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greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
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8381
Table4_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …”
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8382
Table2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …”
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8383
Table3_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …”
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8384
Table1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …”
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8385
Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Transcriptome sequencing and analysis identified 35 genes with significantly altered expression levels due to STZ and CPGB treatment in hippocampal tissues, which were enriched in the Tlr4/Myd88/NF-κB signaling pathway. …”
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8386
Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway
Published 2025“…</p> <p>We demonstrated that the PCG collagen sponge effectively reduced the infiltration of inflammatory cells in the pulp. PCG significantly alleviated the inflammatory response by reducing the mRNA expression levels of IL-1β, IL-6, IL-8, ICAM-1, and VCAM-1 and the secretion of IL-6 and IL-8 in a concentration-dependent manner. …”
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8387
Supplementary file 1_Clinical application of combined anticoagulation therapy in anti-MDA5 antibody-positive associated interstitial lung disease-a retrospective study.docx
Published 2025“…</p>Results<p>At 4-week treatment and 3-month follow-up, the combined anticoagulation group had superior Forced Vital Capacity (FVC)%, Diffusing Capacity of the Lung for Carbon Monoxide (DLCO)%, and Arterial Partial Pressure of Oxygen (PaO<sub>2</sub>) levels compared to the control group (P < 0.05). Meanwhile, C-Reactive Protein (CRP), Lactate Dehydrogenase (LDH), and Creatine Kinase (CK) levels decreased significantly. …”
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8388
Data Sheet 1_Dietary canthaxanthin improves egg production rate through regulating hepatic lipid metabolism and redox status in indigenous chickens.docx
Published 2025“…At week 9, 8 mg/kg CX significantly decreased serum MDA levels (p < 0.05). …”
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8389
Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx
Published 2025“…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”
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8390
Supplementary file 1_Mechanistic insights into the PAI-1 inhibitor PAItrap3: enhancing lipid metabolism in adipose tissue of diabetic db/db mice.xlsx
Published 2025“…Regarding the autophagy pathway, PPARGC1B, LC3B, and PGC1α expression levels were increased, while P62 and Parkin levels were decreased. …”
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8391
Table 2_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx
Published 2025“…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”
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8392
Data Sheet 1_Allicin ameliorates acute myocardial infarction in rats by modulating calcium homeostasis in cardiomyocytes through the induction of hydrogen sulfide production.docx
Published 2025“…</p>Results<p>The results indicate that allicin significantly enhanced cardiac function, raised H<sub>2</sub>S levels in myocardial tissue and serum, reduced necrosis tissue size, decreased myocardial enzyme levels, and improved myocardial pathological changes. …”
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8393
Proteomic and Functional Analysis on Endothelial Cell Heterogeneity Identifies Key Regulators in Hyperglycemia-Induced Dysfunction-Supplemental Materials
Published 2025“…Furthermore, under high glucose conditions, WARS1 was increased while SOD2 was decreased. Reversing WARS1 or SOD2 expression levels improved HDMVEC migration and permeability functions. …”
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8394
Image 1_Lipid biomarkers of GVHD in allogeneic stem hematopoietic cell transplantation patients.png
Published 2025“…Patients with grade III–IV acute graft-versus-host disease (GVHD) exhibited significantly lower HDL-C levels compared to those without GVHD. …”
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8395
Data Sheet 1_Water quality and fluorescent dissolved organic matter dynamics of Dhaleshwari River.pdf
Published 2025“…The river water quality values were compared to the recommended standards of the Environmental Conservation Rules (ECR), and it was observed that the BOD and COD levels exceeded the limits. The water quality index (WQI) values showed that river water is extremely polluted, and the values significantly increased from the upstream to the Keraniganj BSCIC area. 3DEEM-PARAFAC analysis confirmed the presence of protein-like substances, terrestrial humic and fulvic acids, and degraded fulvic acids in the samples, which provided evidence of organic matter pollution. …”
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8396
Table 1_Lipid biomarkers of GVHD in allogeneic stem hematopoietic cell transplantation patients.docx
Published 2025“…Patients with grade III–IV acute graft-versus-host disease (GVHD) exhibited significantly lower HDL-C levels compared to those without GVHD. …”
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8397
Image 1_Genome-wide analysis of lncRNA in wheat (Triticum aestivum) and functional characterization of TalncR9 in response to drought stress.jpeg
Published 2025“…Silencing TalncR9 in wheat reduced drought tolerance, decreased soluble sugar and proline levels, and increasing MDA levels. …”
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8398
Table 1_Genome-wide analysis of lncRNA in wheat (Triticum aestivum) and functional characterization of TalncR9 in response to drought stress.xlsx
Published 2025“…Silencing TalncR9 in wheat reduced drought tolerance, decreased soluble sugar and proline levels, and increasing MDA levels. …”
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8399
Data Sheet 1_Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease.docx
Published 2025“…The MR analysis results showed a positive correlation between higher genetic predictions of dopamine 3-O-sulfate levels and the risk of Parkinson’s disease. In contrast, the reverse MR analysis found that Parkinson’s disease susceptibility significantly increased dopamine 3-O-sulfate levels.…”
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8400
Table 1_Nanocarrier-mediated RNAi of CYP9E2 and CYB5R enhance susceptibility of invasive tomato pest, Tuta absoluta to cyantraniliprole.docx
Published 2025“…Notably, nanocarrier-encapsulated dsRNA targeting CYB5R and CYP9E2 genes significantly reduced their expression levels. Further, the activity of cytochrome P450 was substantially decreased after the knockdown of the CYB5R and CYP92 genes. …”