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121
The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption
Published 2022“…The differentiation, survival and resorptive activity of osteoclasts prepared from Pml−/− mice was increased compared with wild type. Furthermore, the inhibitory effect of IFN-γ on osteoclast formation from Pml−/− was significantly blunted compared with wild type. …”
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Genotypic and phenotypic characterization of candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin. (c2018)
Published 2018“…Our results demonstrate an inverse correlation between resistance and virulence whereby resistance is due to thickening of the cell wall preventing the cell from gaining virulence attributes, while a more susceptible cell wall increases susceptibility to drugs but allows increased virulence.…”
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masterThesis -
124
STARD 13 in prostate cancer. (c2018)
Published 2018“…Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …”
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masterThesis -
125
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Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
Published 2024“…The hematological parameters red blood corpuscles (RBCs), hemoglobin (Hb), and packed cell volume (PCV) were improved significantly (P<0.001) in CURNPs150 and CURNPs100 groups, while CURNPs150 had the lowest values of monocytes (P = 0.019) and heterophils (P<0.005) when compared with other groups. …”
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128
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129
Designing a Flexible and Reconfigurable Manufacturing System Considering a Circular Shaped Layout
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doctoralThesis -
130
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131
Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor—An Opportunity for Cancer Treatment
Published 2019“…There is increasingly evidence that TNFR2 expression in cancer microenvironment has significant implications in cancer progression, metastasis and immune evasion. …”
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132
MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the...
Published 2020“…In the current study, we investigated the role of miR-3148 in regulating human stromal (mesenchymal) stem cell (hMSC) differentiation and transformation. Stable expression of miR-3148 in telomerized hMSC (hMSC-miR-3148) led to significant increase in in vitro adipocytic differentiation and suppression of osteoblastic differentiation. …”
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Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy
Published 2020“…Analysis of HLA-A*0201 responses revealed a significant T cell activation after stimulation with peptide pools 2 (PP2) and 8 (PP8). …”
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Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesen...
Published 2022“…In addition, a significant increase in stemness marker aldehyde dehydrogenase (ALDH1) was observed. …”
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
Published 2020“…Finally, we looked at the effect of HuArgI (Co)-PEG5000 on 3D motility of the ovarian cancer cell line, using a collagen based assay. It showed that SKOV3 cell line does not show significant invasiveness to collagen. …”
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masterThesis -
138
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139
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Immunoprofile of childhood diabetes
Published 2023“…In all clinical phenotypes (obese, Pre-diab, T2D and T1D) CD4+ Treg cells showed increased expression of CD49d in comparison to controls, whereas in Tcon cells differences only were observed in the T2D group. …”