Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy حسب Nassiba Taib (14557385)

"…Interestingly, in the metastatic 1872 Col cells treated with DAC, the expression of both PD-L1 and NY-ESO-1 was increased tenfold (*p = 0.0128) and fivefold (***p < 0.0001), respectively.…"

Beyond genetics: Exploring the role of epigenetic alterations in breast cancer حسب Kirti S. Prabhu (4246144)

"…Central to the progression of breast cancer are epigenetic aberrations, which significantly contribute to drug resistance and the emergence of cancer stem cell traits. …"

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone حسب Abdoulaye Diane (14152749)

"…In the current investigation, we assessed whether ALA has an effect on modulating the expression of DNAJB3/HSP40 cochaperone; a potential therapeutic target with a novel role in mitigating metabolic stress and promoting insulin signaling. Treatment of C2C12 cells with 0.3 mM of ALA triggers a significant increase in the expression of DNAJB3 mRNA and protein. …"

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…RNA-sequencing analysis further validated the findings by showing a significant increase in genes associated with lipid metabolism, bile acid secretion, and suggested the activation of hepatic stellate cells and hepatic fibrosis in MH lacking FOXA2. …"

Thermodynamic Analysis of an Integrated Hydrogen Production System Based on Solar and Nuclear Energy Sources in the UAE حسب Babu, Binish Sam

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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report حسب Fawzia M. Elgharbawy (17045534)

"…<h3>Background</h3><p dir="ltr">Autoimmune lymphoproliferative syndrome (ALPS) is a rare disease characterized by defective FAS signaling, which results in chronic, nonmalignant lymphoproliferation and autoimmunity accompanied by increased numbers of “double-negative” T-cells (DNTs) (T-cell receptor αβ+ CD4−CD8−) and an increased risk of developing malignancies later in life.…"

COVID-19 biomarkers for severity mapped to polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

"…<p dir="ltr">Large scale multi-omics analysis has identified significant differences in the biomarkers between COVID-19 disease and control subjects [1]. …"

20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway حسب Stephanie Eid (440990)

"…In our study, we show that exposure of rats proximal tubular epithelial cells to high glucose (HG) resulted in increased extracellular matrix accumulation and hypertrophy. …"

Orofacial Clefts حسب El Baba, Nada

"…We found no significant differences in the proliferative abilities of the patient-derived cells and the healthy cells. …"
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Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back حسب Lenka Koklesova (18102994)

"…However, this deficiency can be improved by using nanotechnological approaches, solid dispersions, microemulsions or biofortification that significantly increase the anti-cancer and pro-apoptotic efficacy of carotenoids. …"

The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study... حسب Nasser M Rizk (18810328)

"…The increase of Treg cells postoperative is significantly lower compared to lean subjects, p < 0.05. …"

MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM حسب Ramesh Elango (7542068)

"…Mechanistically, forced expression of hsa-miR-205-5p, or hsa-miR-214-3p epigenetically inhibited MDA-MB-231 cell proliferation, colony formation, and cell migration. …"

Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women حسب Vijay Ganji (8710491)

Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment حسب Alanod D. AlQahtani (18805930)

Differing endometrial expression of calcium modulating transient receptor potential channels حسب Maryam Ghavideldarestani (11862563)

"…<p dir="ltr">To the editor</p><p dir="ltr">Assisted reproductive techniques (ART) have increased the live birth success rate, but there is still a significant implantation failure rate. …"

Investigating the suitability of poly tetraarylphosphonium based anion exchange membranes for electrochemical applications حسب Muthumeenal Arunachalam (11450796)

"…<div><p>Anion exchange membranes (AEMs) are becoming increasingly common in electrochemical energy conversion and storage systems around the world (EES). …"

An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films حسب Zulfikre Esa (19457344)

"…The root-mean-square roughness was found to vary significantly with the annealing temperature and the flow rate and ranged from 1.938 to 3.345 nm. …"

Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy حسب Duaa Azam (22502048)

"…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …"