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301
Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
Published 2016“…In conclusion, thymoquinone increased the effectiveness of the chemotherapeutic reagent topotecan by inhibiting proliferation and lowering toxicity through p53- and Bax/Bcl2-independent mechanisms.…”
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302
Mitigation of Greenhouse Gas Emissions from Agricultural Fields through Bioresource Management
Published 2022“…Soil moisture was also impacted by soil temperature and rainfall events. There was a significant effect of events of data collection, i.e., the length of the growing season (p-value ≤ 0.05) on soil surface temperature, leading to increased GHG emissions during the summer months. …”
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303
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304
How does AI affect the mental health of students and teachers
Published 2025“…This study aims to analyze AI's effects on mental health, identifying both positive and negative consequences. …”
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305
Characterization of the dynamic flow response in microfluidic devices
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306
Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size
Published 2023“…</p><h3>Results</h3><p dir="ltr">Prior to TTh interruption, it was observed that testosterone stimulation improved the men’s IPSS, AMS and post-voiding residual bladder volume, while their prostate volume significantly increased. During the TTh interruption, there was a significant worsening in these parameters, although the increase in prostate volume continued. …”
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307
Advanced Thermal Management in Intermittent Electronics: Integrating Metal Foam and Phase Change Materials
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308
AI Integration Within the Architectural Design Process and Management, and its Influence on Project Agility: A Literature Review, Bibliometric, and Survey Analysis
Published 2024“…The findings reveal that AI integration significantly enhances project agility and outcomes, primarily through increased design creativity and automation in project management. …”
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309
The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption
Published 2022“…The differentiation, survival and resorptive activity of osteoclasts prepared from Pml−/− mice was increased compared with wild type. Furthermore, the inhibitory effect of IFN-γ on osteoclast formation from Pml−/− was significantly blunted compared with wild type. …”
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310
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …”
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311
Job satisfaction and organizational climate in the UAE work context
Published 2009“…This obvious change in the UAE job environment has led to an increase in emphasis on effective human resource management especially in ensuring employees’ job satisfaction as a means of maintaining high levels of motivation and increased input. …”
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312
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model
Published 2017“…Finally, reactive oxygen species (ROS) production was significantly accentuated in S+MI group concomitant with a significant increase in NOX-4 protein levels. …”
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313
Aortic stiffness, living donors, and renal transplantation
Published 2006“…In subjects with renal disease, reduced renal function and increased arterial stiffness are significantly associated in cross-sectional studies. …”
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314
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Results: When applied separately, topotecan and andrographolide both exhibited anti-proliferative effects in a dose-dependent manner. Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. …”
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315
Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan
Published 2022“…ART has significantly increased the life expectancy of people living with HIV/AIDS (PLWHA). …”
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316
Risk factors for stoma outlet obstruction: systematic review and meta-analysis
Published 2025“…<h3 dir="ltr">Introduction</h3><p dir="ltr">Stoma outlet obstruction (SOO) is a serious postoperative complication that can lead to significant morbidity, including prolonged hospitalization, increased healthcare costs, and reduced quality of life. …”
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317
Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk
Published 2015“…Results rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) are significantly associated with an increased risk of CAD with respective odds ratios of 1.53703, 1.67710, and 1.35520; the genetic variant rs9579646 (ALOX5AP) is significantly associated with a decreased risk of CAD (OR 0.76163). …”
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318
Local Over-Expression of VEGF-DDNDC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis
Published 2014“…There was a tendency to higher UABF in Ad.VEGF-DΔNΔC compared to Ad.LacZ transduced UtAs (50.58% v/s 26.94%, p = 0.152). There was no significant effect on maternal haemodynamics. An increased number of proliferating endothelial cells and adventitial blood vessels were observed in immunohistochemistry. …”
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319
20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
Published 2013“…In conclusion, we show that hyperglycemia in diabetes has a significant effect on the expression of Arachidonic Acid (AA)-metabolizing CYPs, manifested by increased AA metabolism, and might thus alter kidney function through alteration of type and amount of AA metabolites.…”
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320
Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound.
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doctoralThesis