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561
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …"
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562
Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection
منشور في 2024"…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…"
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563
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…We characterized variants in <i>CCL5</i> and that of six other CCL5 signaling genes (<i>CCND1, ZMIZ1, CASP8, NOTCH2, MAP3K21, and HS6ST3</i>) among 1,082 unrelated Tunisian subjects (544 BC patients, including 196 TNBC, and 538 healthy controls), assessed the association of the variants with BC-specific overall survival (OVS) and progression-free survival (PFS), and correlated CCL5 mRNA and serum levels with <i>CCL5</i> genotypes. We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"
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564
Evaluating the Effectiveness of a Behavioural Training Programme for Primary School Teachers in Al Dhafra Private Schools to Modify the Behaviour of Students With ASD
منشور في 2024"…Additionally, there was a high level of teacher confidence in applying behaviour modification techniques, particularly Applied Behaviour Analysis (ABA), post-training. …"
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565
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …"
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566
Comparison of Capture Hi-C Analytical Pipelines
منشور في 2022"…We consider the effect of retaining multi-mapping reads and compare the efficiency of different statistical approaches in both identifying reproducible interactions and determining biologically significant interactions. At restriction fragment level resolution, the number of multi-mapping reads that could be rescued was negligible. …"
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567
Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016)
منشور في 2016"…Cancer incidence has been increasing worldwide in the last few decades. Solid tumors are hard to treat, primarily due to drug resistance as well as to the struggle in delivering the drugs specifically to the tumor. …"
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masterThesis -
568
Road deaths and injuries in India: Action required on the five pillars of road safety
منشور في 2015"…The economic losses from road crashes are estimated to be 3% of GDP and are increasing from year to year (2). Amidst significant regional variations, many Indian states have road deaths much above the national average. …"
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569
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570
Toxicity assessment of di(2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential
منشور في 2024"…They are added to plastics to increase their flexibility and softness. Phthalate plasticizers including the Di-2-ethylhexyl phthalates (DEHP) are toxic and induce adverse effects on the different organization levels of the environment. …"
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571
Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back
منشور في 2020"…However, this deficiency can be improved by using nanotechnological approaches, solid dispersions, microemulsions or biofortification that significantly increase the anti-cancer and pro-apoptotic efficacy of carotenoids. …"
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572
Determinants of Domestic Workers' Employment
منشور في 2012"…Controlling for household, household head, dwelling, and regional characteristics, we find that the probability of hiring a domestic worker is significantly higher for larger households, female headed households, larger dwellings, and increases with aggregate household consumption. …"
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conferenceObject -
573
TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
منشور في 2019"…Low power consumption has become one of the major requirements for most microelectronic devices and systems. Increasing power dissipation may lead to decreasing system effciency and lifetime. …"
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article -
574
Exploring beyond numeric weight loss: The metabolic effects of semaglutide
منشور في 2025"…Semaglutide also slowed weight regain and promoted weight loss after failed <u>bariatric surgery.</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …"
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575
Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat
منشور في 2007"…Cardiac pacing slightly increased mean AP (0.8 ± 0.2 mmHg/Hz) and decreased pulse pressure (−3.6 ± 0.3 mmHg/Hz) while leaving the mean level of RSNA essentially unaltered (P = 0.680, repeated-measures ANOVA). …"
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article -
576
Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
منشور في 2018"…</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2018.00592" target="_blank">https://dx.doi.org/10.3389/fendo.2018.00592</a></p>…"
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577
The effects of Organisational Ambidexterity and New Public Management on Public Sector Service Quality through Service Innovation
منشور في 2020"…Moreover, the bureaucratic structure of the public sector hinders any initiative to improve, meet the demand for better products and services and operate without necessarily increasing its expenditures and disbursements. Hence, the need to reduce bureaucracy may give rise to the increasing demand for service innovation to attain service quality and enhance performance. …"
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578
Optimization of Electric Vehicles Wireless Charging
منشور في 2019احصل على النص الكامل
doctoralThesis -
579
The landscape of PreK-12 engineering online resources for teachers
منشور في 2015"…Introducing engineering at the Prekindergarten through 12th grade (PreK-12) education level requires significant changes in teacher preparation and support. …"
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article -
580
Accessibility first: detecting frustration in web browsing for visually impaired and sighted smartphone users
منشور في 2023"…When VI participants experienced a session timeout, they significantly showed a higher level of arousal. When comparing the physiological responses of sighted and VI participants in the page refresh and session timeout tasks, the results show that the arousal level is significantly higher in VI participants, primarily due to accessibility issues.…"